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Microbiology PhD Projects, Programs & Scholarships in Sheffield

We have 9 Microbiology PhD Projects, Programs & Scholarships in Sheffield

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  Identifying new drugs to combat the virulence mechanisms underlying multidrug-resistant typhoid.
  Dr D Humphreys
Applications accepted all year round
Multidrug-resistant typhoid. --------------------------------------------. The world is facing an epidemic of multidrug-resistant (MDR) typhoid fever.
  Investigating the molecular mechanism of inflammatory bowel disease
  Dr K Erdmann
Applications accepted all year round
Cohn’s disease together with ulcerative colitis (UC) are the two main variations of inflammatory bowel disease (IBD). 2.5-3 million people in Europe are affected by inflammatory bowel disease with a direct healthcare cost of 4.5-6 billion Euro per year.
  Stressing the superbug. Using bacterial stress sensors to target antimicrobial resistant Staphylococcus aureus.
  Dr R Corrigan, Prof S Renshaw
Application Deadline: 1 June 2019
The “superbug”, Methicillin resistant Staphylococcus aureus (MRSA) is a major threat to global health. Bacteria can sense external stresses such as nutrient deprivation, which promotes antimicrobial tolerance and drives chronic infections.
  The Bacterial Cell Wall in Life and Death
  Prof S J Foster
Applications accepted all year round
The bacterial cell wall is essential for viability. The synthesis of its major structural polymer, peptidoglycan, is the target of crucial antibiotics such as penicillin and vancomycin.
  Staphylococcus aureus Infection Dynamics
  Prof S J Foster
Applications accepted all year round
S. aureus is a major human pathogen of increasing importance due to the spread of antibiotic resistance. It can cause a wide range of diseases, from superficial skin infections to life threatening endocarditis and septicaemia.
  Characterisation of bacterial effectors delivered by the type VI secretion system
  Dr M Thomas
Applications accepted all year round
Many bacterial virulence determinants are secreted proteins referred to as ’effectors’ that benefit the pathogen by allowing it to subvert, damage or kill the host.
  Construction of synthetic organelles for biotechnology
  Dr E Hettema
Applications accepted all year round
This synthetic biology project aims to improve fine chemical production in yeast. This will be achieved by compartimentalisation of novel biosynthetic functions into yeast peroxisomes.
  Engineering non-model yeasts with biotechnological potential
  Dr E Hettema
Applications accepted all year round
The biochemical industry is moving away from a reliance on fossil fuels to produce fine chemicals and is exploring the use of microbes as cell factories.
  Investigating Organelle movement and inheritance by using a combination of yeast genetics, cell and molecular biology and live cell imaging
  Dr E Hettema
Applications accepted all year round
With every cell division cycle, organelles duplicate and are segregated between progeny cells. Cells have evolved organized ways of organelle segregation.
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