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Molecular Biology PhD Projects, Programs & Scholarships in Sheffield

We have 34 Molecular Biology PhD Projects, Programs & Scholarships in Sheffield

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  Developing culture models of the degenerate IVD niche to test Notochordal cell therapies
  Prof C Le Maitre, Prof C Sammon
Application Deadline: 31 March 2019
A 3.5 year full-time PhD scholarship is offered by Sheffield Hallam University, UK. Funding is available for. UK Students & EU Students.
  Development and testing of small molecule NUDT22 inhibitors for uses in cancer
  Dr T Helleday, Dr P Herr
Application Deadline: 28 February 2019
The INTEGRATA network –“Integrating chemical and biological approaches to target NAD production and signaling in cancer” – aims at providing a group of early stage researchers (ESRs) with a highly interdisciplinary and intersectoral training in drug discovery, focusing specifically on NAD production and on NAD/nucleotide signaling as targets for the development of new cancer therapeutics.
  Extracellular Vesicles: small packages with a big role in bowel cancer metastasis
  Dr N J Peake, Dr L Cole, Prof C Le Maitre
Application Deadline: 31 March 2019
Project details. Background. Patients with metastatic colorectal cancer (CRC) have poor survival rates, reflecting the difficulty in treating advanced disease.
  Spin-orbit coupling in synthetic semiconductor-protein complexes for solar energy harvesting
  Research Group: Biological Physics
  Dr J Clark, Prof C N Hunter
Application Deadline: 31 March 2019
Singlet fission is a process whereby one photon creates two excited states. This two-for-one mechanism could dramatically increase solar cell efficiency (from 33% to >40%).
  Elucidating the molecular function of SNAP29 a gene mutated in CEDNIK syndrome
  Dr A Peden
Applications accepted all year round
CEDNIK (cerebral dysgenesis, neuropathy, ichthyosis and keratoderma) syndrome is a rare fatal disease caused by the loss of SNAP29.
  Homeostatic balancing of neuronal excitation and inhibition in vivo
  Dr A Lin
Applications accepted all year round
Neuronal excitation and inhibition are very carefully balanced in the brain, and perturbed excitation/inhibition (E/I) balance has been linked to diseases such as epilepsy, autism and schizophrenia.
  Imaging neurotransmitter release to measure synaptic plasticity underlying associative memory
  Dr A Lin
Applications accepted all year round
How does the brain encode memories? We think learning occurs by changes in the strength of synaptic connections between neurons, but the precise mechanisms by which this synaptic plasticity occurs is often unknown.
  Identifying new drugs to combat the virulence mechanisms underlying multidrug-resistant typhoid.
  Dr D Humphreys
Applications accepted all year round
Multidrug-resistant typhoid. --------------------------------------------. The world is facing an epidemic of multidrug-resistant (MDR) typhoid fever.
  Deciphering Roles of SUMOylation in mini-Human Brains in Health and Disease
  Dr C Guo, Dr S Brown
Applications accepted all year round
Neurodegenerative disorders and cerebral ischemia are incurable conditions, imposing tough medical challenges and a substantial economic burden on health services.
  Investigating the role of the mechanosensor channel Piezo1 in human disease
  Dr K Erdmann
Applications accepted all year round
Piezo proteins are ion channels that are gated by mechanical stimuli like stretch or shear stress. In mammalians there are two Piezo isoforms (Piezo1 and Piezo2) with largely different expression pattern.
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