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University of Oxford, Sir William Dunn School of Pathology PhD Projects, Programs & Scholarships

We have 22 University of Oxford, Sir William Dunn School of Pathology PhD Projects, Programs & Scholarships

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  A molecular analysis of centrioles, centrosomes and cilia
  Prof J Raff
Application Deadline: 10 January 2020

Funding Type

PhD Type

Centrioles are barrel-shaped structures that organise the assembly of two crucial cell organelles. centrosomes and cilia.
  Anti-inflammatory actions of metabolites on macrophages and microglia
  Prof D R Greaves
Application Deadline: 10 January 2020

Funding Type

PhD Type

Background. It is clear that inflammation underlies many important chronic disease states in both the central nervous system (CNS) e.g.
  Control of T cell activation by accessory receptors
  Dr O Dushek
Application Deadline: 10 January 2020

Funding Type

PhD Type

T cells orchestrate immune responses crucial for the elimination of infections and cancers. They do this by initiating a diverse set of effector responses when their T cell surface receptors (TCRs) recognize these threats.
  Development and validation of new tools to dissect the molecular functions of caspases in non-apoptotic scenarios.
  Dr L A Baena-López
Application Deadline: 10 January 2020

Funding Type

PhD Type

The apoptotic function of caspases has overshadowed other important roles linked to these evolutionary conserved enzymes during many years.
  Developmentally regulated expression of the transcription factor PRDM1 in the mouse
  Prof E Robertson
Application Deadline: 10 January 2020

Funding Type

PhD Type

The master transcriptional regulator Blimp-1/PRDM1 contains an N-terminal PR/SET domain and five C2H2 zinc fingers located near its C-terminus that mediate DNA binding, nuclear import, and recruitment of histone modifying enzymes.
  Exploring Parkinson’s related gene function in hiPS-macrophages and microglia
  Prof W S James, Dr S Cowley
Application Deadline: 10 January 2020

Funding Type

PhD Type

The macrophage is an evolutionarily ancient sentinel of the health of all of the body’s tissues. clearing away dead cells and debris; as brain-resident microglia, remodelling defunct neuronal connections; nurturing tissue stem cells; detecting and responding to pathogens.
  Flaviviral manipulation of autophagy for biogenesis and evasion of host immune responses
  Dr S Sanyal
Application Deadline: 10 January 2020

Funding Type

PhD Type

This project will investigate mechanisms of flavivirus biogenesis, with particular emphasis on Zika and Dengue. Current understanding on how progeny virions are assembled and secreted is limited.
  Homologous recombination: when, where and how does it act?
  Dr F Esashi
Application Deadline: 10 January 2020

Funding Type

PhD Type

Our genomic DNA is constantly challenged by numerous environmental stresses, such as radiation and genotoxic drugs, as well as those arising from normal processes of cell growth, including DNA replication and transcription.
  Intronic gene silencing: new mechanism of gene expression regulation and its relevance to cancer
  Dr M Gullerova
Application Deadline: 10 January 2020

Funding Type

PhD Type

Mammalian cells employ small RNAs (sRNAs) molecules to regulate gene expression in a pathway known as RNA interference (RNAi). Transfer RNAs (tRNAs) are essential for translation but also serve as a source for tRNA-derived small RNAs (tsRNAs).
  Mechanisms controlling organelle dynamics and quality control
  Prof P Carvalho
Application Deadline: 10 January 2020

Funding Type

PhD Type

Our lab is interested in membrane-bound organelles- how they form and acquire their distinctive proteome essential to carry their specialized functions.
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