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University of Oxford, Sir William Dunn School of Pathology PhD Projects, Programs & Scholarships

We have 21 University of Oxford, Sir William Dunn School of Pathology PhD Projects, Programs & Scholarships

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Sir William Dunn School of Pathology  University of Oxford

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We have 21 University of Oxford, Sir William Dunn School of Pathology PhD Projects, Programs & Scholarships

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Investigating the mechanism maintaining centromere integrity

The centromere is a region of chromatin that serves as a platform for the kinetochore machinery assembly, hence is essential for accurate chromosome segregation during cell division. Read more

Organelle dynamics in health and disease

The inside of a cell is crowded with many different organelles. For example, cells typically contain hundreds of mitochondria that produce energy, and hundreds of peroxisomes that make important chemicals. Read more

RNA biology in neurons

Multiple neuronal processes, including axon guidance, learning and memory, rely on asymmetric localisation and translation of mRNAs within a neuron. Read more

Viral manipulation of host cell biology for assembly, secretion and immune evasion.

This project will investigate mechanisms of assembly, secretion and immune subversion adopted by (+)RNA viruses, with a particular emphasis on Dengue/Zika from the flavivirus and SARS-CoV-2 from the coronavirus families. Read more

Discovery, selection and proof of concept evaluation of selective therapeutic targets in sarcoma.

In the last decade, forward translation of NGS sequencing in cancers has resulted in the discovery of numerous driver variants, large scale single gene CRISPR screens have identified functional targets for translational validation and yet very few targets have been confirmed as effective in clinical testing. Read more

The role of TIRR in DNA damage response

Efficient DNA damage response (DDR) is a fundamental process for every living organism. The accumulation of DNA damage affects cell viability and leads to a variety of diseases, particularly cancer. Read more

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