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We have 7 Structural Biology (agents) PhD Projects, Programmes & Scholarships

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Structural Biology (agents) PhD Projects, Programmes & Scholarships

We have 7 Structural Biology (agents) PhD Projects, Programmes & Scholarships

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Understanding centrosome function in the human airway

Breathing sustains our life and is also important for our quality of life. Inside the lung, billions of hair-like structures called cilia beat a million times a day to promote a process called mucociliary clearance. Read more

NIHR Leeds BRC: Pre-clinical evaluation of novel regenerative medicine strategies for knee osteoarthritis

Historically, articular cartilage was considered incapable of spontaneous repair.  However, biomechanical correction in osteoarthritis (OA) using high tibial osteotomy or joint distraction demonstrated the remarkable joint to regeneration by “merely” correcting joint alignment. Read more

Alterations in reparative dentinogenesis with ageing, gender and genetic predisposition

Dental pulp exposure caused by tooth decay or injury can lead to life-threatening infections. Following injury, reparative dentinogenesis serves a vital purpose through the accelerated generation of tertiary dentine, comprising mineral and type I collagen. Read more

Viral-surface interactions studied by vibrational sum-frequency spectroscopy

The recent COVID-19 pandemic, and in particular fomite transmission of the virus, led to a lot of interest in how viral particles attached to surfaces, their survival times on different materials and how they transferred to hosts. Read more
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