Structural Biology (cells) PhD Projects, Programmes & Scholarships

We have 44 Structural Biology (cells) PhD Projects, Programmes & Scholarships

Molecular mechanism of vimentin induced epithelial mesenchymal transition (EMT) and stemness in cancer cells

Queen Mary University of London Institute of Dentistry

Background. Most cancers are epithelial in origin and arise from a single progenitor cell, similar to an embryo, to become a clone of cells. Read more

Supervisors: Prof A Waseem, Dr H Tummala, Dr F Flores-Borja

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Supervisors: Dr JF Fox, Dr JH Hodgkinson

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Probing Death Decisions from Morphogen Gradient Fields

University of Liverpool Department of Molecular and Clinical Cancer Medicine

Morphogen gradient scaling is one of the hottest fields in developmental biology at the moment. Scaling is fundamental, explaining how the machinery that controls pattern formation in development (the morphogens) can adapt, so that organs of different sizes show morphological structures which are proportioned. Read more

Supervisor: Dr MM Merino

Year round applications PhD Research Project Self-Funded PhD Students Only

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Possible role of mutant vimentin in cancer progression and metastasis

Queen Mary University of London Institute of Dentistry

Background. This project will investigate the role of the cytoskeletal protein vimentin in cancer progression and metastasis using cell and molecular biology approaches. Read more

Supervisors: Prof A Waseem, Dr F Flores-Borja, Dr H Tummala

Year round applications PhD Research Project Self-Funded PhD Students Only

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Taking Light Induced Electron Paramagnetic Resonance In Cell for Biological Structural Determination

The University of Manchester Department of Chemistry

Studying the structure of proteins and other biological systems is an important step in understanding their function. Most structural studies are conducted in environments that are far away from native conditions, such as those found inside a cell. Read more

Supervisors: Dr A Bowen, Dr J Rowbotham, Dr I Riddell, Dr D Heyes

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Targeting Ras palmitoylation for the treatment of cancer

University of Dundee School of Medicine

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Supervisor: Dr N Fraser

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Epigenetics of early human development: From molecular mechanisms to regenerative medicine

University of Leicester Molecular and Cell Biology

The 46th chromosome in XX female mammals, the second X, has to be switched off. That way females equalize gene dosage of X-linked genes with XY males. Read more

Supervisors: Dr Y Markaki, Prof J Schwabe, Dr JH Hodgkinson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding control of genome folding by cohesin

University of Leicester Molecular and Cell Biology

Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more

Supervisors: Prof D Panne, Dr T Schalch

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Obtaining insights into how a signalling hub protein Ras activates multiple effectors

University of Leicester Molecular and Cell Biology

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more

Supervisors: Dr K Tanaka , Dr R Mahen

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Epigenetics of early human development: From molecular mechanisms to regenerative medicine

University of Leicester Molecular and Cell Biology

Ever wondered how nature maintains balance of gene expression between sex chromosomes? Well, the 46th chromosome of XX females, the second X, has to be switched off. Read more

Supervisors: Dr Y Markaki, Dr T Schalch

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Molecular characterization of Sam68-driven cytoskeletal reorganization

University of Leicester Molecular and Cell Biology

The cytoskeleton is a complex network of various fibres (microtubules, actin, …) that is essential for cells to maintain their shape and internal organization and for their migration. Read more

Supervisors: Dr C Dominguez, Prof A Fry

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Alpha-synuclein amyloid in Parkinson's disease: using Nanoinjection as a tool to study alpha-synuclein amyloid toxicity inside neurons

University of Leeds Faculty of Biological Sciences

Intraneuronal inclusions known as Lewy bodies are a hallmark of Parkinson’s disease. Amyloid fibrils formed by the misfolding of alpha-synuclein are the principal component of Lewy Bodies. Read more

Supervisors: Dr E W Hewitt, Prof S E Radford, Dr P Actis

Year round applications PhD Research Project Self-Funded PhD Students Only

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How does myosin 10 contribute to filopodia formation and stability?

University of Leeds Faculty of Biological Sciences

How do cells make filopodia? Filopodia are thin protrusions that act as pathfinders in cell migration, helping cells to sense where to go, and pulling cells through the extracellular matrix, especially important in driving cancer cell metastasis. Read more

Supervisors: Prof M Peckham, Dr D Tomlinson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-funded PhD- Understanding Cell Biology through Imaging

University of Bristol School of Biochemistry

We study the trafficking and interaction of molecules and structures inside cells. Extracellular signals need to be processed in a correct manner for a cell to function properly. Read more

Supervisor: Prof P Verkade

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-funded MSc R: Understanding Cell Biology Through Imaging

University of Bristol School of Biochemistry

We study the trafficking and interaction of molecules and structures inside cells. Extracellular signals need to be processed in a correct manner for a cell to function properly. Read more

Supervisor: Prof P Verkade

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 44 Structural Biology (cells) PhD Projects, Programmes & Scholarships

Structural Biology (cells) PhD Projects, Programmes & Scholarships

We have 44 Structural Biology (cells) PhD Projects, Programmes & Scholarships

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