Structural Biology (drug design) PhD Projects, Programmes & Scholarships

We have 7 Structural Biology (drug design) PhD Projects, Programmes & Scholarships

(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health

We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more

Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Control and inhibition of virus replication

University of Leeds Faculty of Biological Sciences

The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets. Read more

Supervisor: Dr A.K Tuplin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Exploring Viral Nucleic Acid Machinery via Cryo Electron Microscopy to Advance Biomedicine

University of York York Biomedical Research Institute

Viruses, these tiny but potent life forms, are all around us, infecting various organisms and directly affecting human health. Although in most cases, viral infection is not life threatening, in the minority of cases it leads to long-term disorders including cancer. Read more

Supervisors: Prof F Antson, Dr J Gordeeva, Dr P Bardy

Year round applications PhD Research Project Self-Funded PhD Students Only

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In Silico targeting of unstructured extracellular histones: En route to a new horizon of drug discovery to target disordered proteins) – second call for applications

Maastricht University Cardiovascular Research Institute Maastricht (CARIM)

Applications can only be submitted via our website. The specific position for Doctoral Candidate 6 (DC6) in the consortium, which is part of Work Package 2 (WP2), aims. Read more

Supervisor: Dr G Nicolaes

30 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Virology: Unique Antiviral Therapy targeting Zika and Related Viruses

University of Leeds Faculty of Medicine and Health

Zika Virus (ZIKV) has emerged as a new mosquito-borne threat to public health after the devastating South American outbreak. Read more

Supervisors: Dr S Griffin, Dr A Kalli, Dr C McKimmie

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Supervisors: Dr JF Fox, Dr JH Hodgkinson

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Development of LA1011 for high affinity binding to Hsp90 for use towards healthy ageing in patients showing Alzheimer’s symptoms

University of Sussex School of Life Sciences

Research Group: Biochemistry

With 50 million global cases of Alzheimer’s disease (AD) and care costs of 1 trillion UK pounds (expected to triple by 2050), there is a pressing need to slow disease progression, sustain productive lives and reduce costs. Read more

Supervisor: Dr C Prodromou

5 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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We have 7 Structural Biology (drug design) PhD Projects, Programmes & Scholarships

Structural Biology (drug design) PhD Projects, Programmes & Scholarships

We have 7 Structural Biology (drug design) PhD Projects, Programmes & Scholarships

(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

Control and inhibition of virus replication

Exploring Viral Nucleic Acid Machinery via Cryo Electron Microscopy to Advance Biomedicine

In Silico targeting of unstructured extracellular histones: En route to a new horizon of drug discovery to target disordered proteins) – second call for applications

Virology: Unique Antiviral Therapy targeting Zika and Related Viruses

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

Development of LA1011 for high affinity binding to Hsp90 for use towards healthy ageing in patients showing Alzheimer’s symptoms

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