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We have 10 Structural Biology (gene expression) PhD Projects, Programmes & Scholarships

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Structural Biology (gene expression) PhD Projects, Programmes & Scholarships

We have 10 Structural Biology (gene expression) PhD Projects, Programmes & Scholarships

Structural investigation of oncogenic splicing factors

More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more

Investigating the role of P2X7 receptor intracellular domains in cell signalling

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

Structure and function of enzyme complexes involved in post-transcriptional gene regulation

Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more

Understanding control of genome folding by cohesin

Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more

Molecular characterization of Sam68-driven cytoskeletal reorganization

The cytoskeleton is a complex network of various fibres (microtubules, actin, …) that is essential for cells to maintain their shape and internal organization and for their migration. Read more

Protein self assembly induced by multivalent biological metabolites

In addition to being an energy source in biological reactions, recent discoveries suggest adenosine triphosphate (ATP) also plays a critical role in maintaining cell stability and preventing deleterious cellular processes through modulating biomacromolecular self assembly. Read more

School of Life Sciences Black Scholars Programme

The School of Life Sciences and the University of Dundee are committed to addressing under-representation in postgraduate research and we are pleased to offer our first Masters by Research Scholarships for UK students from Black or Black-Mixed Backgrounds. Read more
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