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Structural Biology (human) PhD Projects, Programs & Scholarships

We have 44 Structural Biology (human) PhD Projects, Programs & Scholarships

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  Exploiting the true joint progenitor cell for articular cartilage repair
  Prof D Chan
Applications accepted all year round

Funding Type

PhD Type

Articular cartilage facilitates the frictionless motion of synovial joints. However, once damaged from trauma or excessive loading in daily use, repair is very poor leading to osteoarthritis (OA), a huge medical and social burden.
  Mass spectrometry analysis of human tissue to characterise cleavage events resulting in amyloid deposition associated with aortic aneurysm and dissection
  Dr J Madine, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

The most common form of localised amyloid occurs in the aorta (aortic medial amyloid; AMA) and is estimated to occur in 97% of Caucasian people over 50.
  How human teeth form and how that process fails in the inherited condition amelogenesis imperfecta
  Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Amelogenesis is the process of enamel formation and is essential for the development of functional teeth. Amelogenesis imperfecta (AI) is a failure of that process.
  Regulation of genome stability and human disease
  Dr I Ahel
Application Deadline: 10 January 2020

Funding Type

PhD Type

Poly(ADP-ribose) polymerases (PARPs) are the major family of enzymes that synthesize an abundant posttranslational protein modification called ADP-ribosylation.
  Mechanistic, structural, and functional studies of a human carbohydrate processing enzyme
  Research Group: Biomedical Sciences Research Centre
  Dr T Gloster
Application Deadline: 1 December 2019

Funding Type

PhD Type

Carbohydrates, or sugars, are ubiquitous throughout nature and perform a number of important functions in our cells.
  Deciphering protective factors for intervertebral disc degeneration for mechanistic insights and intervention potentials
  Prof D Chan
Applications accepted all year round

Funding Type

PhD Type

Intervertebral disc degeneration (IDD) can lead to a diversity of problems including low back pain and sciatica as two very painful symptomatic outcomes.
  Insights into eye disease: understanding the molecular basis of age-related macular degeneration
  Prof T Day, Dr S Clark
Applications accepted all year round

Funding Type

PhD Type

Dysregulation of innate immunity has been implicated as playing a key role in the development of age-related macular degeneration (AMD) – a major form of blindness in the industrialised world (see [1-5]).
  Ligament and tendon repair using a specific population of joint progenitor cells
  Prof D Chan
Applications accepted all year round

Funding Type

PhD Type

Ligaments and tendons stabilize the musculoskeletal system, controlling mobility. Anterior cruciate ligament in knee joints restrict the dimension of joint movement, while Achilles tendon transmit forces from calf muscle to bone enabling locomotion of ankle joints.
  Molecular mechanisms of genome stability and cancer
  Dr D Ahel
Application Deadline: 10 January 2020

Funding Type

PhD Type

The maintenance of complete and undamaged genome is critical for survival. However, DNA is a fragile structure susceptible to DNA damage.
  Deep Learning / Bioinformatics Approach for Protein-Protein Interaction Prediction
  Dr JC Nebel
Applications accepted all year round

Funding Type

PhD Type

Since most molecular processes rely on protein–protein interactions PPIs), knowledge of those interactions is extremely valuable for biomedical research and drug design.
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