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We have 13 Structural Biology (interaction) PhD Projects, Programmes & Scholarships

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Structural Biology (interaction) PhD Projects, Programmes & Scholarships

We have 13 Structural Biology (interaction) PhD Projects, Programmes & Scholarships

Obtaining an integrated understanding of oncogenic RAS signalling

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more

Self-funded PhD- Understanding Cell Biology through Imaging

We study the trafficking and interaction of molecules and structures inside cells. Extracellular signals need to be processed in a correct manner for a cell to function properly. Read more

Self-funded MSc R: Understanding Cell Biology Through Imaging

We study the trafficking and interaction of molecules and structures inside cells. Extracellular signals need to be processed in a correct manner for a cell to function properly. Read more

Modelling blood motion in deformable vessels

This project aims to introduce a novel approach in studying blood flow in deformable vessels by simultaneously considering both the fluid (blood) and the structure (vessel) through analytical and numerical approaches. Read more

Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more

MSc by Research: How are SUMO substrates selected for modification ?

SUMO has diverse roles in cellular physiology that in most cases are mediated by its ability to interact non-covalently with hydrophobic patches of low sequence complexity known as SUMO Interaction Motifs (SIMs). Read more

Investigating the role of P2X7 receptor intracellular domains in cell signalling

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more
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