Structural Biology (kinase) PhD Projects, Programmes & Scholarships

We have 7 Structural Biology (kinase) PhD Projects, Programmes & Scholarships

Structural and mechanistic studies of fibroblast growth factor receptor signalling

University of Leeds Faculty of Biological Sciences

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisors: Prof A.L. Breeze, Prof F. Sobott

Year round applications PhD Research Project Self-Funded PhD Students Only

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The identification of allosteric inhibitors of high value therapeutic targets

University of Sheffield School of Biosciences

This study will develop a novel approach to identify allosteric inhibitor sites on a wide variety of high-value therapeutic targets, including protein kinases, protein phosphatases and small G-proteins. Read more

Supervisor: Prof J P Waltho

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Supervisors: Dr JF Fox, Dr JH Hodgkinson

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Molecular level understanding of Mycobacterium tuberculosis

University of Leicester Department of Respiratory Sciences

Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more

Supervisors: Dr H O'Hare, Dr N Garton

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Molecular Glues as Novel Tools for Tackling Big Challenges in Human Health

University of Leicester Department of Chemistry

Background. The need for new medicines is greater than ever because of an ageing population and the complex clinical challenges brought about by drug resistance and/or side effects. Read more

Supervisors: Dr RD Doveston, Prof S Macip

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Obtaining an integrated understanding of oncogenic RAS signalling

University of Leicester Molecular and Cell Biology

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more

Supervisor: Dr K Tanaka

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

Supervisors: Dr M Young, Dr J Parker

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 7 Structural Biology (kinase) PhD Projects, Programmes & Scholarships

Structural Biology (kinase) PhD Projects, Programmes & Scholarships

We have 7 Structural Biology (kinase) PhD Projects, Programmes & Scholarships

Structural and mechanistic studies of fibroblast growth factor receptor signalling

The identification of allosteric inhibitors of high value therapeutic targets

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

Molecular level understanding of Mycobacterium tuberculosis

Molecular Glues as Novel Tools for Tackling Big Challenges in Human Health

Obtaining an integrated understanding of oncogenic RAS signalling

Investigating the role of P2X7 receptor intracellular domains in cell signalling

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