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Structural Biology (natural) PhD Projects, Programs & Scholarships

We have 15 Structural Biology (natural) PhD Projects, Programs & Scholarships

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  Elucidating plant alkaloid biosynthesis
  Dr B R Lichman, Dr W Unsworth
Application Deadline: 30 June 2020

Funding Type

PhD Type

Plants are capable of forming complex natural products from simple starting materials. Many of these natural products are bioactive, but access is limited as they are difficult to synthesise using organic chemistry and are present in small quantities in the natural source.
  (A*STAR) Engineering pathways to next generation antibiotics
  Prof J Micklefield, Dr A Green
Application Deadline: 31 January 2020

Funding Type

PhD Type

The provision of new antibiotics to combat antimicrobial resistance (AMR) and to treat neglected tropical diseases (NTD), which are problematic in the developing world, is a major global challenge.
  (BBSRC DTP) Discovery and Editing Pathways to New Antibiotics
  Prof J Micklefield, Prof D Leys, Dr A Green
Application Deadline: 31 January 2020

Funding Type

PhD Type

There is an urgent need for new antibiotics. The majority of antibiotics that are used to treat infectious diseases today are small molecules produced by microorganisms, called natural products, or derivatives thereof.
  Fully-funded PhD positions in several natural sciences & engineering disciplines

Funding Type

PhD Type

Join an internationally renowned scientific community with the Hector FellowPhD program. PhD students benefit not only from the experience of the program, but also from the network of Hector Fellows.
  (BBSRC DTP CASE) Design of a light-driven biocatalyst
  Prof D Leys, Dr S Hay
Application Deadline: 31 January 2020

Funding Type

PhD Type

Illumination is able to unlock a wide range of photochemical reactions, but light is rarely used by living organisms. In fact, to date only three light dependent enzymes have been described in detail.
  (BBSRC DTP CASE) Exploitation of P450 BM3 variants for production of valuable drug metabolites
  Prof A Munro, Prof D Leys
Application Deadline: 31 January 2020

Funding Type

PhD Type

The US Food and Drug Administration (FDA) have recommended that human drug metabolites (as well as their parent drugs) should be subject to testing for safety/toxicity.
  Synthetic Virology: Development of gene delivery vectors/synthetic vaccines
  Research Group: Astbury Centre for Structural Molecular Biology
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

There is worldwide interest in exploiting our modern understanding of genomics to target gene expression therapeutically via a variety of mechanisms, such as transgene insertion and CRISPR-Cas gene editing.
  Designing and evolving plastic-degrading enzymes for new function
  Dr B Lichtenstein, Prof J McGeehan, Dr S Robson
Application Deadline: 7 February 2020

Funding Type

PhD Type

Applications are invited for a fully-funded four year PhD studentship to commence in October 2020. The PhD will be based at the University’s Centre for Enzyme Innovation (CEI), and will be supervised by Dr Bruce Lichtenstein, Prof.
  Structural and time-resolved studies of phage replication in bacterial biofilm
  Dr P Plevka
Application Deadline: 20 February 2020

Funding Type

PhD Type

When Staphylococcus aureus cells form a biofilm in the human body they become shielded from the immune system and highly resistant to antibiotics.
  Structure, dynamics and interactions of Microtubule Associated Protein 2c and bacterial RNA polymerase subunits and sigma factors
  Prof L Zidek, Dr J Hritz
Application Deadline: 20 February 2020

Funding Type

PhD Type

Microtubule associated protein 2c (MAP2c) is a key factor regulating microtubule dynamics in developing brain neurons, and an example of an intrinsically disordered proteins with an important physiological function and detectable structure-function relationship.
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