Structural Biology (protein expression) PhD Projects, Programmes & Scholarships

We have 28 Structural Biology (protein expression) PhD Projects, Programmes & Scholarships

Targeting Ras palmitoylation for the treatment of cancer

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Supervisor: Dr N Fraser

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Supervisors: Dr JF Fox, Dr JH Hodgkinson

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Chemical modification of proteins via metal-mediated processes

University of York York Biomedical Research Institute

Chemically modified proteins can be used to understand, treat, and diagnose disease. However, relatively few chemical reactions can be used to modify proteins, severely limiting the diversity and applications of new technologies. Read more

Supervisors: Dr C Spicer, Dr M Plevin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural investigation of oncogenic splicing factors

University of Leicester Molecular and Cell Biology

More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more

Supervisors: Dr C Dominguez, Prof I Eperon, Prof A Hudson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

Supervisors: Dr M Young, Dr J Parker

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural Biology of Host-Parasite Interactions

Institute of Organic Chemistry and Biochemistry Prague Biochemistry and Molecular Biology

PhD Position in Structural Parasitology. A position for a talented and self-motivated PhD student is open in the structural biology group at IOCB Prague lead by Dr. Read more

Supervisor: Dr S Zoll

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Understanding control of genome folding by cohesin

University of Leicester Molecular and Cell Biology

Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more

Supervisors: Prof D Panne, Dr T Schalch

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Revealing Reactivity in Cancer-Associated Heme Proteins: Novel Time-Resolved Structural Approaches

University of Leicester Molecular and Cell Biology

Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme-containing enzyme involved in the degradation of tryptophan to kynurenine. Cancer cells upregulate IDO1 to escape normal immune responses and, in many cases, a high expression of IDO1 is connected to poor prognosis. Read more

Supervisors: Dr HK Kwon, Dr P A Ash

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Chemical energy conversion in biology studied using advanced spectroscopic and structural tools

University of Leicester Department of Chemistry

Redox properties of metal-containing active sites are critically important to many biocatalytic processes. one third of all proteins contain a redox-active metal, and ca 22% of submissions to the Protein Data Bank contain a transition metal. Read more

Supervisors: Dr PA Ash, Dr H Kwon

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Chemical energy conversion in biology studied using advanced spectroscopic and structural tools

University of Leicester Department of Chemistry

Graduate Teaching Assistantship. This is a Graduate Training Assistantship (GTA), which means that you will be required to do some teaching, particularly lab demonstrating, as part of your training. Read more

Supervisor: Dr P Ash

22 April 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Structural and functional characterisation of bacterial virulence factors

Kingston University Faculty of Health, Science, Social Care and Education

In the current era of growing antibiotic resistance, the world needs new therapeutics against bacterial infections as well as new vaccines. Read more

Supervisor: Dr E Lamber

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Fully funded PhD student position in structural biology of viruses

Umeå University Chemistry Department

PhD position in the structural biology of viruses. The Department of Chemistry is opening a PhD position in Chemistry with a specialization in structural biology. Read more

Supervisor: Dr M Renner

2 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Virology: Unique Antiviral Therapy targeting Zika and Related Viruses

University of Leeds Faculty of Medicine and Health

Zika Virus (ZIKV) has emerged as a new mosquito-borne threat to public health after the devastating South American outbreak. Read more

Supervisors: Dr S Griffin, Dr A Kalli, Dr C McKimmie

Year round applications PhD Research Project Self-Funded PhD Students Only

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Unlocking the Secrets of Genome Regulation through cryo-EM

University of Leicester Molecular and Cell Biology

Are you an ambitious spirit, ready to make breakthrough discoveries at the frontier of epigenetics? Dive deep into the fascinating world of eukaryotic genomes with us! . Read more

Supervisors: Dr T Schalch, Dr AC Chaplin

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Possible role of mutant vimentin in cancer progression and metastasis

Queen Mary University of London Institute of Dentistry

Background. This project will investigate the role of the cytoskeletal protein vimentin in cancer progression and metastasis using cell and molecular biology approaches. Read more

Supervisors: Prof A Waseem, Dr F Flores-Borja, Dr H Tummala

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 28 Structural Biology (protein expression) PhD Projects, Programmes & Scholarships

Structural Biology (protein expression) PhD Projects, Programmes & Scholarships

We have 28 Structural Biology (protein expression) PhD Projects, Programmes & Scholarships

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