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Structural Biology (recombinant) PhD Projects, Programs & Scholarships

We have 17 Structural Biology (recombinant) PhD Projects, Programs & Scholarships

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  Recombinant pseudorabies virus as a multivalent vectored vaccine platform for emerging and endemic porcine diseases
  Prof S Graham, Prof D Werling, Prof T Mettenleiter
Application Deadline: 7 February 2020

Funding Type

PhD Type

Pseudorabies virus (PrV), the causative agent of the Aujeszky’s disease, is responsible for substantial losses to the expanding pig industry in Southeast Asia.
  Oxidative protein folding of industrially and pharmaceutically important recombinant proteins
  Dr H Lu, Dr A Day
Applications accepted all year round

Funding Type

PhD Type

Oxidative protein folding is an important process for the function of many proteins, which includes both folding and formation of native disulphide bonds.
  Developing a virus-like particle (VLP) Polio vaccine
  Dr G Mulley
Applications accepted all year round

Funding Type

PhD Type

Rationale. Poliovirus is a non-enveloped RNA virus, spread via the faecal-oral route, that causes the infectious disease Poliomyelitis (Polio).
  Mini Centre for Doctoral Training: Overcoming drug-resistant microbial infection – Targeting the power of Molecular Machines
  Dr E Main, Prof RW Pickersgill, Dr V Darbari, Dr A Kang
Application Deadline: 31 January 2020

Funding Type

PhD Type

The newly formed “Centre for Structural Medicine” (joint between the Schools of Biological and Chemical Sciences and Medicine and Dentistry) is seeking PhD applicants for their fully funded mini Centre for Doctoral Training (CDT) to start in September 2020.
  Structural studies of the TPLATE complex
  Dr K Tripsianes
Application Deadline: 20 February 2020

Funding Type

PhD Type

The TPLATE complex (TPC) is essential for endocytosis in plants, yet it is evolutionary lost from yeasts and animals, pointing to the fact that endocytosis is mechanistically regulated differently.
  The role of protein-protein interactions in the dynamics of m6A RNA modification and the role of posttranscriptional RNA modifications in cell differentiation
  Prof S Vanacova
Application Deadline: 20 February 2020

Funding Type

PhD Type

The internal mRNA modifications play crucial roles in a number of essential processes of eukaryotic organisms. They regulate the production of germ cells, cellular differentiation, response to stress, and defects in this pathway have been linked to a number of human diseases.
  (BBSRC DTP) Mechanism of early steps in protein synthesis by cryoEM imaging of supramolecular complexes
  Dr A Roseman, Prof G D Pavitt, Prof C Baldock
Application Deadline: 31 January 2020

Funding Type

PhD Type

The aim of this project is to understand the mechanism and control of protein synthesis in eukaryotic cells at the molecular level, particularly focused around the role of the eukaryotic translation initiation factors eIF2, eIF5 and eIF2B.
  (BBSRC DTP) Understanding structure and function of the mechanosensors talin and vinculin
  Dr C Ballestrem, Prof C Baldock, Dr A Roseman
Application Deadline: 31 January 2020

Funding Type

PhD Type

The ability of cells to sense biochemical and mechanical properties of their extracellular matrix (ECM) environment is critical for the development of functional tissue.
  Structure/function studies of component proteins of anti-feeding prophage (Afp), a bacteriophage tail-like particle using high-resolution cryo-EM and x-ray crystallography
  Prof A Mitra
Applications accepted all year round

Funding Type

PhD Type

We are seeking a highly motivated candidate to carry out structure/function studies of component proteins of anti-feeding prophage (Afp), a bacteriophage tail-like particle using high-resolution cryo-EM and x-ray crystallography.
  Understanding how the NuRD complex regulates 3D genome organization using a combination of single-molecule super-resolution imaging and single cell biology
  Prof E D Laue
Applications accepted all year round

Funding Type

PhD Type

The spatial organisation of the genome is known to play an important role in regulating RNA transcription to effect cell-type-specific gene expression programs, and to control the differentiation of embryonic stem (ES) cells.
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