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Structural Biology (structural) PhD Projects, Programs & Scholarships

We have 58 Structural Biology (structural) PhD Projects, Programs & Scholarships

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We have 58 Structural Biology (structural) PhD Projects, Programs & Scholarships

Sizing up viruses: application of emerging structural techniques for the characterization of rAAVs

Curious how viruses are used to deliver genetic cargoes to cells? Want to know how we can employ this principle in vaccines and fight cancer? Then this CASE PhD studentship at the University of Leeds, in collaboration with AstraZeneca (Cambridge), might be for you. Read more

NMR spectroscopy in structural biology

1.) NMR method development. NMR is a versatile technique that is used to study structure, dynamics and various functional aspects of proteins and their complexes with their interaction partners. Read more

Structural biology of the Ccr4-Not nuclease complex using electron paramagnetic resonance (EPR) spectroscopy and integrative modelling

The ultimate goal in molecular biology is to understand normal physiology and disease processes at atomic resolution. Methods such as x-ray crystallography and NMR spectroscopy have been phenomenally successful in the past decades and continue to be the workhorses of structural biology. Read more

Understanding the structural consequences of ribosome specialisation

Protein synthesis by ribosomes (translation) and its regulation is essential to life. While it has been traditionally thought that ribosomes were not involved in the regulation of translation, it is now becoming clear that they do contribute. Read more

Using cryoEM to understand pathogen antibiotic transport and resistance

Background. A number of dangerous pathogens are increasingly resistant to our front-line antibiotics, raising the prospect of a ‘post-antibiotic era’ where we can no longer treat infectious diseases. Read more

Ion channel clustering in neuronal membranes

The aim of the study is to investigate the organization of ion channels in the membranes of excitable cells by scaffold proteins, and to discover how the properties of the channels are modified by these interactions. Read more

Structural analysis of the inter-membrane bacterial secretosome

Protein secretion is essential for life. Bacteria secrete proteins for a wide range of membrane and extracellular activities, including envelope biogenesis, pathogenicity and degradation of antibiotics. Read more

Neuroinflammation in Alzheimer’s disease: what is the role of amyloid-beta fibril structure?

This project will explore the role of amyloid-beta fibril structure in triggering neuroinflammation in Alzheimer’s disease. Alzheimer’s disease is the most common form of dementia and affects millions worldwide. Read more

Unravelling the structure and conformational dynamics of membrane proteins using H/D-exchange mass spectrometry and cryo-EM

A dynamic studentship which includes experience working in both academic and pharmaceutical industry environments. the project is performed in partnership between laboratories at both King’s College London and UCB Pharma (Slough, 20 miles West of Central London). Read more

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