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Structural Biology (unknown) PhD Projects, Programs & Scholarships

We have 7 Structural Biology (unknown) PhD Projects, Programs & Scholarships

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  Development of novel cancer treatments: structural studies of Nectin 4 in complex with bespoke anti-cancer peptides – to start October 2019 - for an MSc by Dissertation (MSD)
  Dr F Prischi, Dr V Bavro
Application Deadline: 1 July 2019

Funding Type

PhD Type

Scientific background. This project targets the current gap in therapeutic approaches targeting Triple Negative Breast Cancer (TNBC) that, unlike other breast cancer subtypes, lacks recommended chemotherapy treatment.
  The mechanism of regulation of protein synthesis via eIF2 molecular complexes
  Dr A Roseman, Prof G D Pavitt
Applications accepted all year round

Funding Type

PhD Type

Control of protein synthesis is critical for normal metabolism, development and responses to stress. One major pathway is called the integrated stress response (ISR) and centres on translational control of the general protein synthesis factor eIF2B via the phosphorylation of eIF2 [1,2].
  Understanding structure and drug binding in the multidrug pump ABCG2
  Dr I Kerr, Dr R Layfield
Applications accepted all year round

Funding Type

PhD Type

ABCG2 is one of three human ATP binding cassette transporters that are functionally capable of exporting a diverse range of substrates from cells.
  DNA Damage and Repair: Studying DNA damage and repair to understand the causes of cancer and improve its treatment
  Prof P McHugh, Prof J Rehwinkel, Prof A Harris
Application Deadline: 26 July 2019

Funding Type

PhD Type

Our DNA is constantly under threat from damaging agents. If unrepaired this DNA damage can lead to errors during genome duplication, including the mutations that can lead to cancer and other human diseases.
  Bioinformatics studies of protein structures, functions and their interactions
  Dr L J McGuffin
Applications accepted all year round

Funding Type

PhD Type

The computational study of protein structures, functions and their interactions is fundamental to our understanding of disease.
  Hijacking of host cellular functions and metabolism in MRSA pathogenesis
  Dr M Letek, Dr V Behrends, Dr Y Calle
Applications accepted all year round

Funding Type

PhD Type

Applications are invited from potential PhD candidates to work at the Department of Life Sciences, University of Roehampton, supervised by Dr Michal Letek, Dr Volker Behrends, and Dr Yolanda Calle-Patino.
  Self-association of the Alzheimer’s peptide Aβ on membrane surfaces
  Prof M P Williamson
Applications accepted all year round

Funding Type

PhD Type

Alzheimer’s disease is a neurodegenerative disease that is particularly common amongst the elderly. It accounts for about 65% of all cases of dementia, and affects about 6% of people over 65, rising to 50% of people over 85.
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