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Structural Biology (infection biology) PhD Projects, Programs & Scholarships

We have 12 Structural Biology (infection biology) PhD Projects, Programs & Scholarships

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  Molecular mechanisms of herpesviral infection
  Dr A Golovanov
Applications accepted all year round

Funding Type

PhD Type

Herpes viruses are known to cause a wide range of human diseases, ranging from simple cold sores to cancer, Kaposi Sarcoma. Kaposi Sarcoma, for example, is a type of cancer which affects immunocompromised patients and is endemic in Africa, where it is linked with the spread of HIV infection and AIDS.
  The chemical glycobiology of carbohydrate metabolism
  Prof R Field, Prof S Flitsch
Applications accepted all year round

Funding Type

PhD Type

Carbohydrates are widespread in nature and fulfil many important biological functions. However, the biology of carbohydrates is much less well explored than that of nucleic acids and proteins.
  Evolutionary insights for engineering improved globin oxygen carriers
  Dr M Berenbrink, Dr J Madine
Applications accepted all year round

Funding Type

PhD Type

Around 2 million red blood cell units at a cost of 120.00 GBP per unit are transfused annually in England alone (http://www.nhsbt.nhs.uk/what-we-do/blood-transfusion/).
  Exploiting druggability host spots in protein phosphatase targets
  Dr L Tabernero, Prof D Procter, Dr S Butterworth
Applications accepted all year round

Funding Type

PhD Type

In the past years the use of virtual screening or computer-based screening of compound libraries against selected targets has expanded exponentially the boundaries of drug discovery.
  How do fat cells cause muscle wasting in cancer?
  Prof G Gould, Dr M Cunningham
Application Deadline: 14 April 2020

Funding Type

PhD Type

This project is one of 16 four year PhD Studentships funded by Medical Research Scotland (https://www.medicalresearchscotland.org.uk) to be delivered jointly by the named University and External Partner Organisation (EPO).
  Synthetic Virology: Development of gene delivery vectors/synthetic vaccines
  Research Group: Astbury Centre for Structural Molecular Biology
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

There is worldwide interest in exploiting our modern understanding of genomics to target gene expression therapeutically via a variety of mechanisms, such as transgene insertion and CRISPR-Cas gene editing.
  Treatment of multi-drug resistant infections using a novel, rapid and customised synthetic phage therapy platform.
  Dr K Weynberg
Application Deadline: 30 April 2020

Funding Type

PhD Type

Antimicrobial resistance is increasing at an alarming rate globally. Therefore, there is an urgent need to develop alternative, and potentially complementary, therapeutics to combat pathogenic microbes.
  PhD Studentship in Biosciences - Stopping a killer superbug: unravelling the molecular mechanisms of C. difficile sporulation
  Dr P Salgado
Application Deadline: 20 May 2020

Funding Type

PhD Type

Overview. Interested in a PhD studying antibiotic resistant bacteria and identifying new avenues to treat drug-resistant infections? In this PhD, you will use biochemistry and structural biology, together with molecular biology, genetics and microbiology to understand C.
  Developing a virus-like particle (VLP) Polio vaccine
  Dr G Mulley
Applications accepted all year round

Funding Type

PhD Type

Rationale. Poliovirus is a non-enveloped RNA virus, spread via the faecal-oral route, that causes the infectious disease Poliomyelitis (Polio).
  The role of Efflux in Antibiotic Resistance of Clinically Relevant Pathogens
  Dr J Blair
Applications accepted all year round

Funding Type

PhD Type

Antibiotics underpin all of modern medicine; they are used to treat bacterial infections, and to prevent infections after surgery and in patients with a suppressed immune system such as those undergoing cancer chemotherapy or organ transplantation.
  Modelling of Oral Neutrophil Epithelial interactions
  Dr E Hagi-Pavli
Applications accepted all year round

Funding Type

PhD Type

Background and Clinical Significance. Neutrophils are an important and vital cellular component of the innate immune system providing rapid protection against microbial invasion.
  (A*STAR) Engineering the recognition of antibodies by bacterial superantigens
  Prof J P Derrick, Dr F Hayes
Application Deadline: 17 April 2020

Funding Type

PhD Type

Superantigens are proteins which have the ability to cause hyperactivation of T cells; they are produced by certain bacteria or viruses as a defence mechanism against attack by the immune system.
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