Structural Biology (enzyme) PhD Projects, Programmes & Scholarships for UK Students

We have 10 Structural Biology (enzyme) PhD Projects, Programmes & Scholarships for UK Students

Sustainable Commodity Chemicals through Enzyme Engineering & Design (SuCCEED) - 4 posts available

The University of Manchester Department of Chemistry

SuCCEED is a BBSRC-funded Prosperity Partnership multi-million project between The University of Manchester and Shell. Commodity chemicals are produced on a global scale and normally derived from finite geological sources. Read more

Supervisors: Dr N Dixon, Dr J Esteban Serrano, Prof A Green, Prof D Leys, Dr V Spallina, Prof M Turner, Dr J Winterburn

30 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Revealing Reactivity in Cancer-Associated Heme Proteins: Novel Time-Resolved Structural Approaches

University of Leicester Molecular and Cell Biology

Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme-containing enzyme involved in the degradation of tryptophan to kynurenine. Cancer cells upregulate IDO1 to escape normal immune responses and, in many cases, a high expression of IDO1 is connected to poor prognosis. Read more

Supervisors: Dr HK Kwon, Dr P A Ash

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health

We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more

Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Chemical energy conversion in biology studied using advanced spectroscopic and structural tools

University of Leicester Department of Chemistry

Redox properties of metal-containing active sites are critically important to many biocatalytic processes. one third of all proteins contain a redox-active metal, and ca 22% of submissions to the Protein Data Bank contain a transition metal. Read more

Supervisors: Dr PA Ash, Dr H Kwon

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Natural products in bacterial physiology and chemical interaction

University of Leicester Department of Genetics and Genome Biology

Microbial natural products have diverse chemical structures and bioactivities, which range from cell-cell signalling, nutrient acquisition, antifungal and antibacterial activity to stress resistance (1). Read more

Supervisors: Dr C Jenul, Prof D Jones

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Molecular level understanding of Mycobacterium tuberculosis

University of Leicester Department of Respiratory Sciences

Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more

Supervisors: Dr H O'Hare, Dr N Garton

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Molecular Glues as Novel Tools for Tackling Big Challenges in Human Health

University of Leicester Department of Chemistry

Background. The need for new medicines is greater than ever because of an ageing population and the complex clinical challenges brought about by drug resistance and/or side effects. Read more

Supervisors: Dr RD Doveston, Prof S Macip

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Molecular characterization of Sam68-driven cytoskeletal reorganization

University of Leicester Molecular and Cell Biology

The cytoskeleton is a complex network of various fibres (microtubules, actin, …) that is essential for cells to maintain their shape and internal organization and for their migration. Read more

Supervisors: Dr C Dominguez, Prof A Fry

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Novel glycoprotease discovery and characterisation for enhanced detergent performance

Newcastle University BiSCoP CTP

In this exciting joint academia-industry project the student will exploit metagenomes and the huge untapped capacity of the human gut microbiota to breakdown glycoconjugates to discover novel protease enzymes that can potentially increase the performance and environmental sustainability of leading P&G automatic dishwashing brands. Read more

Supervisors: Dr E Lowe, Dr D Bolam, Dr AL Morales Garcia, Mrs K Bell-Rusiewicz

2 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Last chance to apply

In Silico targeting of unstructured extracellular histones: En route to a new horizon of drug discovery to target disordered proteins) – second call for applications

Maastricht University Cardiovascular Research Institute Maastricht (CARIM)

Applications can only be submitted via our website. The specific position for Doctoral Candidate 6 (DC6) in the consortium, which is part of Work Package 2 (WP2), aims. Read more

Supervisor: Dr G Nicolaes

30 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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We have 10 Structural Biology (enzyme) PhD Projects, Programmes & Scholarships for UK Students

Structural Biology (enzyme) PhD Projects, Programmes & Scholarships for UK Students

We have 10 Structural Biology (enzyme) PhD Projects, Programmes & Scholarships for UK Students

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