Structural Biology PhD Projects, Programmes & Scholarships for UK Students

Ariel University Chemical Sciences

Crystallization of membrane proteins

We aim at developing a. SIMPLE-TO-IMPLEMENT and GENERAL crystallization approach for membrane proteins (MPs). Read more

Supervisor: Dr G Patchornik

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

University of Edinburgh School of Biological Sciences

Understanding the molecular basis of piRNA-directed DNA methylation in the mammalian germline

Research Group: Institute for Regeneration and Repair

In mammals, transposons are silenced throughout most of life by DNA methylation. The mammalian germline is derived from somatic cells early during development. Read more

Supervisor: Prof D O'Carroll

17 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

The University of Manchester Department of Chemistry

Hybrid Mass Spectrometry Methods to Determine Structure Activity Relationships for Photocatalytic Enzymes

This project will use ion mobility mass spectrometry, photoactivation, soft landing and single molecule imaging to understand enzyme structure function relationships. Read more

Supervisors: Prof P Barran, Prof N Scrutton, Dr D Heyes

1 February 2024 PhD Research Project Funded PhD Project (UK Students Only)

University of Nottingham Researcher Academy

RNA In Situ-ations: Unravelling the Molecular Basis for Myotonic Dystrophy through HighResolution Cryo-Electron Tomography of Disease State RNA Condensates

We aim to uncover the molecular mechanisms underlying RNA misfolding diseases, particularly focusing on myotonic dystrophy (DM). In DM, both voluntary and involuntary muscles progressively degenerate in the body, affecting normal functioning of the eye, heart, endocrine system and central nervous system. Read more

Supervisor: Prof J D Brook

12 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

University of Dundee School of Life Sciences

China Scholarship Council: Structural and Mechanistic Chemical Biology of Degraders Mode of Actions

Pioneering discoveries from the Ciulli Laboratory and others have contributed to the establishment of a new modality of chemical intervention into biological systems. Read more

Supervisors: Prof A Ciulli, Prof R Hay

31 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Designed Protein and Lipid Nanostructures

Advances in protein design are beginning to allow us to build novel protein nanostructures with unique functions. These nanomachines include programmable artificial cages that can be endowed with dynamic capabilities such as the ability to open and close under specific conditions of interest. Read more

31 January 2024 PhD Research Project Funded PhD Project (UK Students Only)

Structural and Functional Studies of DNA Gyrase: A Fascinating Nanomotor

DNA gyrase is a remarkable enzyme that not only supercoils DNA but also functions as an intricate nanoscale motor with moving parts that coordinate their movements in a particular, defined sequence. Read more

31 January 2024 PhD Research Project Funded PhD Project (UK Students Only)

Engineering Artificial Protein Cages With New Capabilities

Step into the cutting-edge world of protein design with a PhD researching Artificial Protein Cages (APCs). APCs have vast potential with applications ranging from revolutionary vaccine development to state-of-the-art drug delivery systems. Read more

31 January 2024 PhD Research Project Funded PhD Project (UK Students Only)

Biological Nanorobotics: Pioneering DNA/RNA and Artificial Protein Nanostructures

Project Description. Make your mark in the burgeoning field of Biological Nanorobotics! In this project you will bring together DNA/RNA nanotechnology with protein design to imagine and build new hybrid structures which together will provide novel structural and functional capabilities not previously realised. Read more

31 January 2024 PhD Research Project Funded PhD Project (UK Students Only)

University of Dundee School of Life Sciences

China Scholarship Council: Breaking the barrier: Improving antibiotic design by machine learning

Antibiotic resistance is a global health problem of increasing severity. Infections caused by Gram-negative bacteria are especially difficult to treat… Read more

Supervisors: Prof U Zachariae, Dr R Sknepnek

31 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

University of Leicester Department of Chemistry

Using CryoEM to trap and visualise PROTAC drugs in action against cancer targets

We invite applicants for a 4-year iCASE studentship to work in collaboration with our industrial partner Peak Proteins, part of Sygnature Discovery. Read more

Supervisors: Dr JH Hodgkinson, Dr JS Schwabe

12 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

University of Dundee School of Life Sciences

China Scholarship Council: Feel the tension – how does S-acylation of OSCA ion channels regulate responses to environmental change in plants?

Plants, being sessile organisms, must sense and respond to environmental change, such as temperature or drought, without being able to move. Read more

Supervisors: Dr P Hemsley, Prof U Zachariae

31 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Imperial College London MRC Laboratory of Medical Sciences (LMS)

Pluripotency-specific regulation and function of transposable elements in mammalian development

In early development, a single fertilized zygote proceeds through a series of cleavage steps to develop into a multicellular blastocyst. Read more

Supervisor: Dr M Percharde

12 December 2023 PhD Research Project Funded PhD Project (Students Worldwide)

Imperial College London MRC Laboratory of Medical Sciences (LMS)

Deconstructing cell identity control mechanisms operating during embryonic development

The Development and Transcriptional control group, led by Dr Vicki Metzis, focuses on understanding the molecular drivers of cell identity control during embryonic development. Read more

Supervisor: Dr V Metzis

12 December 2023 PhD Research Project Funded PhD Project (Students Worldwide)