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University of Leeds Structural Biology PhD Projects, Programs & Scholarships

We have 9 University of Leeds Structural Biology PhD Projects, Programs & Scholarships

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  Control and inhibition of virus replication
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A.K Tuplin
Applications accepted all year round

Funding Type

PhD Type


The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specificaly Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets.
  Defining a novel assembly pathway in ssRNA viruses using X-ray footprinting.
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

Project co-supervised by Prof. Peter Stockley at Leeds and Prof. Reidun Twarock at University of York, as part of the White Rose network "Structural and Mechanistic Biology at the RNA/Ligand Interface".
  Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas
  Research Group: School of Molecular and Cellular Biology
  Dr J Boyes
Application Deadline: 1 June 2020

Funding Type

PhD Type

V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas.
  Learning from plant cell walls as a path for innovations in food and material sciences
  Dr Y Benitez-Alfonso, Dr C Bosch
Applications accepted all year round

Funding Type

PhD Type

The research will dissect the structural factors controlling cell walls and cell communication for two main purposes. to improve the health value of food crops and to design strategies for the valorisation of wasted plant materials.
  Nanoinjection: a single molecule technique to study amyloid toxicity in neurons
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford, Dr P Actis
Applications accepted all year round

Funding Type

PhD Type

Interested in amyloid disorders such as Parkinson’s and Huntington’s. Want to work with cutting edge technology in a multidisciplinary team.
  Synthetic Virology: Development of gene delivery vectors/synthetic vaccines
  Research Group: Astbury Centre for Structural Molecular Biology
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

There is worldwide interest in exploiting our modern understanding of genomics to target gene expression therapeutically via a variety of mechanisms, such as transgene insertion and CRISPR-Cas gene editing.
  How human teeth form and how that process fails in the inherited condition amelogenesis imperfecta
  Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Amelogenesis is the process of enamel formation and is essential for the development of functional teeth. Amelogenesis imperfecta (AI) is a failure of that process.
  Direct characterisation of TRPC channel dynamics triggered by drug-like modulators using high-speed atomic force microscopy
  Research Group: Molecular and Nanoscale Phsyics
  Dr G Heath
Applications accepted all year round

Funding Type

PhD Type

The rapid expansion in the structural understanding of membrane proteins through recent progress in electron microscopy and X-ray crystallography is leading to an ever greater need for techniques which provide high temporal resolution dynamics.
  Seeing photosynthesis at the nanoscale: mapping physical properties of light-harvesting biomembranes by high-resolution microscopy and spectroscopy
  Research Group: Molecular and Nanoscale Phsyics
  Dr P.G. Adams, Dr G Heath
Applications accepted all year round

Funding Type

PhD Type

Understanding photosynthesis could provide valuable clues for future solar technology and help our understanding of food crops.
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