Synthetic Chemistry (drug discovery) PhD Projects, Programmes & Scholarships

We have 19 Synthetic Chemistry (drug discovery) PhD Projects, Programmes & Scholarships

Data-driven realisation of molecular editing for drug discovery

University of Leeds Faculty of Engineering and Physical Sciences

Drug discovery pipelines are driven by iterative cycles in which molecules are designed, synthesised, purified and tested. A remarkably limited toolkit… Read more

Supervisors: Prof A Nelson, Prof S Marsden

6 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Phosphine Oxides as Rising Stars in Drug Discovery

Imperial College London Institute of Chemical Biology

Phosphine oxides represent a noticeably underrepresented chemotype in drug discovery. Read more

Supervisor: Dr J Bull

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Photoredox molecular editing for enhanced drug discovery

The University of Manchester Department of Chemistry

Molecular editing platforms, the process by which single atoms can be inserted or deleted selectively in or around a molecule’s skeleton, are transformative to synthetic chemists across industry and academia for the streamlined development of new drugs. Read more

Supervisor: Dr A Trowbridge

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

University of Leeds Faculty of Biological Sciences

Research Group: Astbury Centre for Structural Molecular Biology

Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more

Supervisors: Prof A O'Neill, Dr M McPhillie, Prof C Fishwick

Year round applications PhD Research Project Self-Funded PhD Students Only

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Towards the development of a novel class of broad-spectrum anti-infective drugs

University of Strathclyde Department of Pure and Applied Chemistry

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more

Supervisor: Dr FS Scott

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular Glues as Novel Tools for Tackling Big Challenges in Human Health

University of Leicester Department of Chemistry

Background. The need for new medicines is greater than ever because of an ageing population and the complex clinical challenges brought about by drug resistance and/or side effects. Read more

Supervisors: Dr RD Doveston, Prof S Macip

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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A reactive fragment approach to dissect the zDHHC enzymes

University of Strathclyde Department of Pure and Applied Chemistry

Key Words: Synthetic Chemistry; Chemical Biology; Drug Discovery; Medicinal Chemistry; Organic Synthesis; Organic Chemistry. Read more

Supervisors: Prof N Tomkinson, Prof L Chamberlain

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry

Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more

Supervisors: Prof E Takano, Prof H Oguri

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Design and synthesis of chemical tools to interrogate cannabinoid receptors - synthetic, medicinal chemistry

University of Otago Department of Chemistry

Research project. We are seeking a highly motivated PhD candidate to join an interdisciplinary team at the University of Otago, to undertake research developing chemical probes for the cannabinoid receptor, a type of G protein-coupled receptor (GPCR). Read more

Supervisor: Dr AJ Vernall

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Enantioselective Cobalt-Catalysed Skeletal Rearrangements

University of St Andrews School of Chemistry

Research in the Johnston group broadly focuses on the development of new catalytic reactions for (i) the streamlined synthesis of known small molecules or (ii) unprecedented access to novel building blocks, with potential applications in drug discovery and agrochemistry. Read more

Supervisor: Dr C P Johnston

Year round applications PhD Research Project Self-Funded PhD Students Only

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Developing new treatments for leishmaniasis

University of Strathclyde Department of Pure and Applied Chemistry

Leishmaniasis. Read more

Supervisor: Dr FS Scott

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design and synthesis of next-generation antibody drug conjugates to target homologous recombination deficient cancers

University of Strathclyde Department of Pure and Applied Chemistry

Background. Antibody-drug conjugates (ADCs) offer a powerful strategy for the cell-selective delivery of therapeutics, while minimizing off-target interactions associated with the drug payload. Read more

Supervisors: Prof G Burley, Dr Z Rattray

3 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Digital discovery of new photocatalysts for photoredox catalysis (EPSRC CDT PhD studentship in collaboration with AstraZeneca)

University of Liverpool Department of Chemistry

Photoredox catalysis has come to the forefront in organic synthesis as a powerful strategy for the activation of small molecules [1]. Read more

Supervisors: Dr JW Ward, Prof A Troisi

30 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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High-throughput biomaterials discovery

The University of Manchester Department of Chemistry

Polymer biomaterials have revolutionised a range of areas from drug delivery, to antimicrobials, to cellular cryopreservation. There are 1000’s of possible monomer combinations, molecular weights and architectures to be explored, and even small differences can dramatically change their properties. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Design and synthesis of a hybrid compound of RAR and VDR

Medical University of Vienna Institute for Pathophysiologie and Allergy

The doctoral candidate (DC) will perform chemical research on the design and organic synthesis of hybrid compounds at the Medical University of Warsaw, Warsaw, Poland. Read more

Supervisor: Prof AK Kutner

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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We have 19 Synthetic Chemistry (drug discovery) PhD Projects, Programmes & Scholarships

Synthetic Chemistry (drug discovery) PhD Projects, Programmes & Scholarships

We have 19 Synthetic Chemistry (drug discovery) PhD Projects, Programmes & Scholarships

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