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Synthetic Chemistry (human) PhD Projects, Programs & Scholarships

We have 11 Synthetic Chemistry (human) PhD Projects, Programs & Scholarships

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  Antibody-drug conjugates (ADCs) for the treatment of solid tumours
  Dr S Karagiannis, Prof J Downward
Application Deadline: 29 November 2019

Funding Type

PhD Type

An Antibody-Drug Conjugate (ADC) comprises an antibody targeted toward a tumour cell surface antigen, coupled through a chemical linker to a highly-cytotoxic drug.
  Designing novel composite polysaccharide nanoparticles for combined diagnosis and treatment of cancers
  Dr E Barbu, Dr A Lalatsa
Applications accepted all year round

Funding Type

PhD Type

Cancer continues to impose a vast burden with regard to financial costs as well as human suffering but the progress in its treatment is hindered by the limited selectivity and significant side-effects that the current chemotherapy demonstrates, representing a major challenge for modern drug delivery.
  Developing an enzymatic toolbox to make complex modified peptides
  Prof M Jaspars, Dr W Houssen, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

The pharmaceutical industry has identified a major gap in its portfolio. On the one hand, they are excellent at discovering small molecules that act via a lock and key type mechanism.
  Genome mining of novel antimicrobial natural products from new bacterial strains
  Dr H Deng, Prof M Jaspars
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Chemically editable 3D tumour microenvironments to explore and exploit tumour immunity
  Dr O Pearce, Dr B Schumann
Application Deadline: 29 November 2019

Funding Type

PhD Type

Immunotherapy of cancers may offer progression free survival that is not seen with conventional chemotherapies. However, immunological barriers present within the tumour reduce response rates to therapy.
  Synthesis and computation to understand and redesign self-assembling carbohydrate materials
  Prof R Field, Dr A Almond
Application Deadline: 30 October 2019

Funding Type

PhD Type

Polysaccharides are widespread in nature and fulfil many important biological functions; they are important foodstuffs and they are exploited as bulk commodities across industry sectors due to their physical properties.
  Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics
  Dr L Wong, Dr C F Blanford
Applications accepted all year round

Funding Type

PhD Type

Plastics are a broad range of solid polymeric materials that have found widespread application as industrial components and consumer goods.
  Tyrosine kinase inhibitors conjugated tumour targeting dyes for the treatment of glioblastoma.
  Dr J Jose, Dr P Choi
Applications accepted all year round

Funding Type

PhD Type

Glioblastoma (GBM) remains a lethal and difficult to treat cancer with a dismal outcome. Although we have a better understanding of the disease progression, a concurrent increase in therapeutic intervention is lagging.
  Inhibitors of cilia and Hedgehog signaling: from phenotype to mechanistic understanding
  Prof S Hoogendoorn
Applications accepted all year round

Funding Type

PhD Type

The Hedgehog (Hh) signaling pathway is a major contributor to embryonic development, and tissue homeostasis and stem cell maintenance in children and adults.
  Neuropeptide Research - PhD Opportunity at a World Class Institution
  Assoc Prof M Muttenthaler, Assoc Prof C Schroeder, Assoc Prof I Vetter
Applications accepted all year round

Funding Type

PhD Type

We are seeking talented and highly motivated PhD candidates for the following multidisciplinary project. Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases.
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