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Synthetic Chemistry (sexual) PhD Projects, Programs & Scholarships

We have 9 Synthetic Chemistry (sexual) PhD Projects, Programs & Scholarships

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  (BBSRC DTP CASE) Discovery and Engineering of Expanded Halogenases for Late Stage Enzymatic Functionalisation
  Prof J Micklefield, Prof P Barran
Application Deadline: 31 January 2020

Funding Type

PhD Type

The project aims to discover and engineer novel enzymes (biocatalysts) that can affect regioselective halogenation of complex molecules enabling more efficient and environmentally sustainable production of pharmaceuticals which are urgently required to combat disease.
  (BBSRC DTP) Biological photocatalysis for sustainable synthesis
  Prof M Greaney, Dr A Green, Dr S Hay
Application Deadline: 31 January 2020

Funding Type

PhD Type

This project will develop biological photochemistry, using proteins as catalysts for new chemical transformations under visible light irradiation.
  (BBSRC DTP) Discovery and Editing Pathways to New Antibiotics
  Prof J Micklefield, Prof D Leys, Dr A Green
Application Deadline: 31 January 2020

Funding Type

PhD Type

There is an urgent need for new antibiotics. The majority of antibiotics that are used to treat infectious diseases today are small molecules produced by microorganisms, called natural products, or derivatives thereof.
  (BBSRC DTP) Discovery, development and application of novel amine and imine biocatalysts for the synthesis of natural products, their analogues and other privileged motifs
  Dr R Whitehead, Prof N Turner, Prof P Barran
Application Deadline: 31 January 2020

Funding Type

PhD Type

This is a cross-disciplinary project, which combines the complementary research expertise of Professor Nick Turner (biocatalysis), Professor Perdita Barran (mass spectrometry) and Dr Roger Whitehead (organic synthesis/biological chemistry).
  (BBSRC DTP) Solubilising Insoluble Proteins using Self-Assembling Supramolecular Structures
  Dr I Riddell, Dr L Wong, Prof P Barran
Application Deadline: 31 January 2020

Funding Type

PhD Type

Protein insolubility is a common problem for researchers working with isolated proteins that, due to hydrophobic patches on their surface, misfold and/or aggregate outside of their natural environment.
  (BBSRC DTP) Selective knockdown of proinflammatory microRNAs to tackle neurodegeneration and cognitive decline: myth or reality?
  Dr E Bichenkova, Prof J Neill, Dr F Roncaroli, Prof D Clarke
Application Deadline: 31 January 2020

Funding Type

PhD Type

Neurodegenerative diseases (e.g. multiple and amyotrophic lateral sclerosis, Alzheimer’s and Parkinson’s diseases) have tremendous psychological, clinical and social impact, which becomes increasingly challenging in the global trend of population aging.
  (BBSRC DTP) Tackling the genomic dark matter through system engineering of ncRNAs in yeast
  Prof D Delneri, Prof P Cai
Application Deadline: 31 January 2020

Funding Type

PhD Type

Non-coding RNAs (ncRNAs) are thought as of genomic "dark matter" for which the biological significance has been largely underestimated.
  (MRC DTP) Design and synthesis of new antivirulence drugs for treatment of tuberculosis
  Dr L Tabernero, Dr S Butterworth, Prof D Procter
Application Deadline: 15 November 2019

Funding Type

PhD Type

Tuberculosis (TB) remains a major health problem that affects billions of people worldwide and the emergence of severe anti microbial resistance (AMR) to current antibiotics is now the main challenge to eradicate the disease.
  (MRC DTP) Design of allosteric small molecule inhibitors of fibrosis using advanced molecular simulation techniques
  Dr R A Bryce, Dr K Piper Hanley, Dr R Whitehead
Application Deadline: 15 November 2019

Funding Type

PhD Type

Integrins are a family of protein receptors that play a major role in cell survival, growth and migration. Their function is to transmit signals across the cell membrane by undergoing an elegant large scale structural rearrangement.
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