About the stegbauerlab. The mission of the stegbauerlab at the Biogenic Engieering Materials group at TU Bergakademie Freiberg is to transform. Read more
Polymers are widespread in modern society as they produce light, strong, and cheap plastic materials, with an ever-increasing demand, which are critical to many technologies from consumer goods, electronics to healthcare. Read more
Air- and moisture-sensitive organometallic reagents are a key tool in modern synthetic chemistry and enable a wide range of powerful synthetic transformations. Read more
There is significant interest in sp3-rich heterocyclic scaffolds for medicinal chemistry and there is thus a need for methods to construct sp3-sp2 bonds on such scaffolds in a simple, controllable, programmable and sustainable way. Read more
The solid phase synthesis of oligonucleotides, historically conducted on controlled pore glass, but more recently on polystyrene, typically proceeds in a 3′ to 5′ direction by a four-step synthesis cycle with each step followed by a solvent wash. Read more
Research project . We are seeking a highly motivated PhD candidate to undertake research developing chemical probes for Phytophthora, including Phytophthora agathidicida. Read more
Cancer has a major impact on society, this is reflected by the large number of newly diagnosed cases (375,400 annually for the years 2015-2018 in the UK, i.e. Read more
Bicyclo[n.1.1]alkanes (BCAs) have emerged as important building blocks in contemporary drug design, serving as useful building blocks that can substitute for aromatic rings, leading to improved physicochemical and pharmacokinetic profiles of drug candidates. Read more
We will establish methods for the synthesis of novel, medicinally important bridged bicyclic hydrocarbon (BBH) scaffolds using late-stage oxygenation enabled by unspecific peroxygenase (UPO) enzymes. Read more
There is much interest in 3D heterocyclic scaffolds for medicinal chemistry. Within fragment-based drug discovery, we are developing a synthetic platform to enable the elaboration of 2D fragments into 3D lead compounds, addressing limitations highlighted by industry. Read more
This project is one of a number that are in competition for funding from the GW4 BioMed2 MRC Doctoral Training Partnership which is offering up to 21 studentships for entry in September 2025. Read more
PhD-Position (m/w/d) - Materials for the detection of minority species in optofluidic waveguides. The detection of pollutants in wastewater, fertilisers in drinking water or biomarkers in medical samples is important for people and the environment. Read more
Even before the current global COVID-19 pandemic, the threat posed to human health by viruses was extensive and although significant progress in targeting some viruses (e.g., HIV-1 and hepatitis C) has been made, challenges remain. Read more
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