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We have 227 Synthetic Chemistry PhD Projects, Programmes & Scholarships
Synthetic Chemistry PhD Projects, Programmes & Scholarships
We have 227 Synthetic Chemistry PhD Projects, Programmes & Scholarships
Dendrimers for Drug delivery
We have worked with a number of water soluble polymer systems capable of encapsulating and solubilising various hydrophobic drug moieties. Despite the formation of stable complexes, we have demonstrated that encapsulated drug can also be released. Read more
Novel Electrochemical and Sonochemical C-H Activation Methods for Heterocycle Synthesis
Saturated oxygen and nitrogen containing heterocycles are widespread across natural products and pharmaceutically active ingredients. Our research… Read more
Medicinal Chemistry PhD Project: Synthesis and biological evaluation of small molecules to target mesothelioma and related ASS1-dependent tumours
Arginine (Arg) is an amino acid critically involved in numerous biological functions including cell proliferation, cell signaling, muscle contraction, immunity… Read more
MSc by Research: Designing Molecular Glue Stabilizers to Restore Tumour Suppressor Function
Molecular glues, small molecules that facilitate the assembly of biomolecular complexes, have emerged as a transformative drug discovery strategy for treating diseases such as cancer and neurodegeneration. Read more
MAX-FOX – Maximising f-element oxidation states
A European Research Council (ERC) funded PhD studentship is available for an aspiring scientist to undertake research in the field of synthetic f-element chemistry. Read more
P9. Dial-a-Solvent: Electrochemical control over surfactant formation and concentration (CSHP CDT)
Surfactants are used in virtually every industry, and there is a high demand for biodegradable surfactants to prevent pollution and increase process efficiency. Read more
P7. Metal catalysed synthesis of complex stereochemically defined nitrogen heterocycles (CSHP CDT)
This project contains exciting opportunities for the production of complex stereochemically defined ‘3D’ heterocycles from simple, easily prepared, ‘2D’ aromatic precursors. Read more
P6. Enantioselective Synthesis, Medicinal Chemistry Applications and Antimicrobial Activity of New Chiral Phosphorous (V) Building Blocks (CSHP CDT)
Molecules containing stereogenic phosphorous (V) atoms are commonplace in bioactive medicines and agrochemicals ranging from. Read more
P25. The catalytic synthesis of sulfonamide and sulfonimidamide building blocks from simple feedstocks (CSHP CDT)
Sulfur derived functional groups are found in medicinal agents used to treat to broad range of indications. Sulfonamides are most common group, featuring in >10% of medicines. Read more
P23. Polymers From Carbon Dioxide: Using Precision Catalysis to Control Polymer Properties (CSHP CDT)
Polymer manufacturing is already responsible for 1.6 Gt CO2 equiv. Read more
P22. CO2 and Bio-derived Oxygenated Polymers to Reduce Adhesives Carbon Footprint (CSHP CDT)
Adhesives play a critical role in many technologies from construction, transportation, electronics to consumer goods. There are growing environmental concerns, legislation and customer pressure to deliver more sustainable adhesives and to ensure they maximise recycling of other components. Read more
P21. Radical polar crossover from the triplet state (CSHP CDT)
New reaction manifolds are valuable for the synthesis of complex molecules. This project will focus on the development of radical-polar crossover reactions by employing visible light mediated energy transfer catalysis to generate complex three-dimensional heterocyclic scaffolds. Read more
P2. New applications of thiophene-S,S-dioxides in sustainable synthesis (CSHP CDT)
Thiophene S,S-dioxides (TDOs) are convenient but underutilised building blocks in organic chemistry. This project will seek to develop new applications of TDOs in sustainable chemical synthesis. Read more
P19. Combatting Antimicrobial Resistance (CSHP CDT)
Resistance to pharmaceuticals, including anti-infectives and cancer drugs, and agrochemicals is a major global health problem. As highlighted by the 2016 O’Neill report, the situation with current antibiotics is perilous. Read more
P18. Synthesis of Aryl-fused Bicyclo[3.1.1]heptanes (BCHeps) and Validation as Heterobiaryl Bioisosteres (CSHP CDT)
While naphthalene and equivalent heterobiaryl rings are often encountered in drugs, candidates and lead molecules, they can be susceptible to cytochrome P450-mediated metabolism and exhibit flat, sp2-rich structures and are almost invariably derived from fossil fuel sources, limiting their current and future utility. Read more