or
Continue with FacebookLooking to list your PhD opportunities? Log in here.
We have 156 Synthetic Chemistry PhD Projects, Programmes & Scholarships for Self-funded Students
Synthetic Chemistry PhD Projects, Programmes & Scholarships for Self-funded Students
We have 156 Synthetic Chemistry PhD Projects, Programmes & Scholarships for Self-funded Students
Drug metabolism - prediction, detection, and isolation
Electrosynthesis (ES) is a green methodology for preparing and interpreting drug metabolites linked to toxicology. ES describes the synthesis of chemical compounds in an electrochemical cell. Read more
Enzymes for Sustainable Amide Synthesis Under Aqueous Conditions for Pharmaceutical Applications
A PhD studentship is available to work on a multidisciplinary project led by Professor Andrew Carnell on the discovery and development of enzymes for application in the sustainable synthesis of amides under aqueous conditions. Read more
The catalytic synthesis of sulfonamide and sulfonimidamide building blocks from simple feedstocks (CSHP CDT)
Sulfur derived functional groups are found in medicinal agents used to treat to broad range of indications. Sulfonamides are most common group, featuring in >10% of medicines. Read more
Metal catalysis for the sustainable synthesis of pharmaceutically relevant heterocycles (CSHP CDT)
Functionalised heterocycles remain the cornerstone of medicinal chemistry programmes, and in particular, heterocycles linked to a second heterocycle or other aromatic group, feature prominently. Read more
Polymers From Carbon Dioxide: Using Precision Catalysis to Control Polymer Properties (CSHP CDT)
Polymer manufacturing is already responsible for 1.6 Gt CO2 equiv. Read more
CO2 and Bio-derived Oxygenated Polymers to Reduce Adhesives Carbon Footprint (CSHP CDT)
Adhesives play a critical role in many technologies from construction, transportation, electronics to consumer goods. There are growing environmental concerns, legislation and customer pressure to deliver more sustainable adhesives and to ensure they maximise recycling of other components. Read more
Radical polar crossover from the triplet state (CSHP CDT)
New reaction manifolds are valuable for the synthesis of complex molecules. This project will focus on the development of radical-polar crossover reactions by employing visible light mediated energy transfer catalysis to generate complex three-dimensional heterocyclic scaffolds. Read more
Combatting Antimicrobial Resistance (CSHP CDT)
Resistance to pharmaceuticals, including anti-infectives and cancer drugs, and agrochemicals is a major global health problem. As highlighted by the 2016 O’Neill report, the situation with current antibiotics is perilous. Read more
Synthesis of Aryl-fused Bicyclo[3.1.1]heptanes (BCHeps) and Validation as Heterobiaryl Bioisosteres (CSHP CDT)
While naphthalene and equivalent heterobiaryl rings are often encountered in drugs, candidates and lead molecules, they can be susceptible to cytochrome P450-mediated metabolism and exhibit flat, sp2-rich structures and are almost invariably derived from fossil fuel sources, limiting their current and future utility. Read more
Sustainable Hydrogen Borrowing Catalysis with Earth Abundant Metals (CSHP CDT)
While hydrogen borrowing (HB) catalysis offers an attractive route for the construction of C-C bonds using alcohols and ketones, current methods rely upon… Read more
Next generation antibiotic siderophores (CSHP CDT)
This project will develop next generation synthetic siderophores - small molecule high affinity iron receptors used by bacteria to accumulate iron. Read more
Micellar organo-catalysis in water using earth abundant main group elements (CSHP CDT)
This project will explore methods to use earth abundant, Lewis acidic main group catalysts to catalyse organic transformations in water by exploiting micellar confinement. Read more
Enantioconvergent Catalytic Fluorination of Alkyl Halides with Alkali Metal Fluoride (CSHP CDT)
The introduction of saturation in the form of C. sp. 3-F into pharmaceutical candidates improves medicinal properties and increases the chance to reach the clinic. Read more
The development of photodynamic surfactants: a new modality to tackle anti-microbial resistance (CSHP CDT)
There is increasing interest in the use of surfactants to tackle key elements of antimicrobial resistance (AMR). Read more
Catalytic asymmetric cross-coupling reactions using non-precious metals (CSHP CDT)
Asymmetric cross-coupling technologies are powerful techniques that represent the state-of-the-art in the construction of chiral small molecules. Read more