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cell therapy PhD Projects, Programmes & Scholarships
We have 34 cell therapy PhD Projects, Programmes & Scholarships
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CAR T cell Immune Therapy for Cancer: Mechanisms and Dynamics explored by Microscopy
Applications are invited for a research studentship leading to the award of a PhD degree. The project will be based in Prof. Dan Davis’s laboratory, based in the South Kensington campus of Imperial College London, funded by a collaboration with the pharmaceutical company Bristol Myers Squibb, based in the USA. Read more
Cardiovascular effects of combination therapy with VEGF inhibitors and immune checkpoint inhibitors in cancer treatment
The success in cancer therapy observed in the past two decades is tightly associated with the introduction of new therapeutic strategies, which include combination therapies. Read more
Stochastic modelling and inference for live-cell gene expression data to unravel the mechanisms of stem cell differentiation
Research Group:
Statistical Medicine and Molecular Biology
This project will develop statistical methodology and computational algorithms to estimate model parameters using live-cell imaging data provided by the lab of our collaborator Dr Cerys Manning at the University of Manchester. Read more
ABM CDT The mechanisms of portable negative pressure wound therapy on wounds
Wounds are a major unmet healthcare burden that impact on millions of patients per year. From those undergoing simple surgeries to complex ulcers of the lower limbs, a common form of therapy is the use of negative pressure wound therapy. Read more
FULLY FUNDED PROJECT - Investigation of the conflicting roles of cell death during colorectal cancer using real-time, in vivo imaging.
'To apply, please click institution web link'*. At a cell autonomous level, apoptotic cell death is inherently anti-tumourigenic and evasion of cell death is a hallmark of cancer. Read more
Last chance to apply
Identification of novel druggable targets in canine insulinoma through single-cell transcriptomic analysis
Project Summary. Insulinomas (INS) are the most common pancreatic neuroendocrine tumours in dogs and humans. Current treatment options in both species are limited to surgery and palliative medical therapy and survival is poor for malignant INS. Read more
PRIORITIZING DRUG COMBINATIONS IN LEUKEMIA BASED ON ANALYSIS OF TARGETTED THERAPY IN VIVO
The inhibition of BCR-associated kinases by so-called B cell receptor signalling inhibitors in B cell leukemia and lymphomas is a potent therapeutic strategy, and several BTK and PI3K kinase inhibitors are available for clinical use (Ondrisova and Mraz, 2020). Read more
The immune milieu of bronchiolitis and impact of bacterial lysates
Background. Overall, 33% of all UK infants will develop clinical bronchiolitis, and 3% of all UK infants will require admission to hospital for this disease. Read more
Exploring the role of matrix encapsulation on early developmental decisions using non-animal sourced hydrogels
A PhD studentship in stem cell biology and disease modelling is available in Prof Merry’s group (. https://www.nottingham.ac.uk/medicine/people/cathy.merry. Read more
Exploring G Protein-Coupled Receptor signaling and dietary oils for treatment of beta cell dysfunction, insulin resistance and inflammation in type 2 diabetes
Research Group:
Biomedical Sciences
The prevalence of type 2 diabetes has risen dramatically during recent decades and there is an urgent need to develop new approaches that provide a combination of benefits, with fewer side effects. Read more
Understanding the chromosome 11 CRC risk locus genes and the role they play in intestinal homeostasis
The 11q23 locus, was identified by GWAS as a CRC risk locus (Tenesa*, Farrington* et al, 2008). The three genes within the locus – C11orf53, COLCA1 and COLCA2 – have also been shown to be eQTLs (expression quantitative trait loci) for regional SNPs in human colonic normal epithelium (Vaughan-Shaw et al, 2021). Read more
THE PRECISION OF NEW THERAPIES FOR INTRAOPERATIVE BRAIN CANCER SURGERY
The clinical need. Glioblastoma is the most aggressive primary brain tumour and the cancer with the most years of potential life lost in adults. Read more
Developing functionalised electrospun scaffolds to exploit neural–stromal interactions in wound healing (Industry Project)
The ABM CDT is a partnership between The Universities of Manchester and Sheffield. ALL APPLICATIONS should however, be submitted via the Manchester application system only. Read more
Developing functionalised electrospun scaffolds to exploit neural–stromal interactions in wound healing (Industry Project)
The ABM CDT is a partnership between The Universities of Manchester and Sheffield. ALL APPLICATIONS should however, be submitted via the Manchester application system only. Read more
4-YEAR DPhil/PhD Studentship: Defining novel DNA repair mechanisms to target in breast cancer treatment
Maintaining genome integrity through DNA repair is critical to guard against a variety of diseases, including cancer. Our research aims to understand these processes, with specific reference to how Poly(ADP-ribose) polymerases (PARPs) regulate genome stability. Read more