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cell therapy PhD Projects, Programmes & Scholarships

We have 34 cell therapy PhD Projects, Programmes & Scholarships

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We have 34 cell therapy PhD Projects, Programmes & Scholarships

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CAR T cell Immune Therapy for Cancer: Mechanisms and Dynamics explored by Microscopy

Applications are invited for a research studentship leading to the award of a PhD degree. The project will be based in Prof. Dan Davis’s laboratory, based in the South Kensington campus of Imperial College London, funded by a collaboration with the pharmaceutical company Bristol Myers Squibb, based in the USA. Read more

Stochastic modelling and inference for live-cell gene expression data to unravel the mechanisms of stem cell differentiation

  Research Group: Statistical Medicine and Molecular Biology
This project will develop statistical methodology and computational algorithms to estimate model parameters using live-cell imaging data provided by the lab of our collaborator Dr Cerys Manning at the University of Manchester. Read more

ABM CDT The mechanisms of portable negative pressure wound therapy on wounds

Wounds are a major unmet healthcare burden that impact on millions of patients per year. From those undergoing simple surgeries to complex ulcers of the lower limbs, a common form of therapy is the use of negative pressure wound therapy. Read more
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Identification of novel druggable targets in canine insulinoma through single-cell transcriptomic analysis

Project Summary. Insulinomas (INS) are the most common pancreatic neuroendocrine tumours in dogs and humans. Current treatment options in both species are limited to surgery and palliative medical therapy and survival is poor for malignant INS. Read more

PRIORITIZING DRUG COMBINATIONS IN LEUKEMIA BASED ON ANALYSIS OF TARGETTED THERAPY IN VIVO

The inhibition of BCR-associated kinases by so-called B cell receptor signalling inhibitors in B cell leukemia and lymphomas is a potent therapeutic strategy, and several BTK and PI3K kinase inhibitors are available for clinical use (Ondrisova and Mraz, 2020). Read more

Understanding the chromosome 11 CRC risk locus genes and the role they play in intestinal homeostasis

The 11q23 locus, was identified by GWAS as a CRC risk locus (Tenesa*, Farrington* et al, 2008). The three genes within the locus – C11orf53, COLCA1 and COLCA2 – have also been shown to be eQTLs (expression quantitative trait loci) for regional SNPs in human colonic normal epithelium (Vaughan-Shaw et al, 2021). Read more

4-YEAR DPhil/PhD Studentship: Defining novel DNA repair mechanisms to target in breast cancer treatment

Maintaining genome integrity through DNA repair is critical to guard against a variety of diseases, including cancer. Our research aims to understand these processes, with specific reference to how Poly(ADP-ribose) polymerases (PARPs) regulate genome stability. Read more

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