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We have 29 differentiation PhD Projects, Programmes & Scholarships for UK Students

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differentiation PhD Projects, Programmes & Scholarships for UK Students

We have 29 differentiation PhD Projects, Programmes & Scholarships for UK Students

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Role of mechanical signals in a 3D human model of alveolar differentiation

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more
 Supervisors: Dr S Loukogeorgakis, Dr F Michielin, Prof P De Coppi
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Stochastic modelling and inference for live-cell gene expression time-series data to unravel the mechanisms of stem cell differentiation

University of St Andrews School of Mathematics and Statistics
  Research Group: Division of Statistics
This project will develop statistical methodology for noisy time-series data and stochastic computational models to analyse live-cell imaging data provided by the lab of our collaborator Dr Cerys Manning at the University of Manchester. Read more
 Supervisor: Dr G Minas
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Human Genetics, Genomics and Disease: Sequence determinants of mRNA fate in neuronal differentiation

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: MRC Human Genetics Unit
Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center Berlin Institute for Medical Systems Biology, Berlin, Germany. Read more
 Supervisor: Dr G Kudla
 19 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Duchenne muscular dystrophy (DMD) is a severe X-linked genetic disorder affecting 1:5000 boys at birth (1). DMD is caused by mutations in Dystrophin gene, with around 10% of the cases caused by nonsense mutations (2,3). Read more
 Supervisors: Dr HZ Zhou, Dr J Meng, Prof F Muntoni
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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The effect of pharmacotherapy on macrophage differentiation and polarization in cardiometabolic disorders

Charles University Faculty of Pharmacy
Faculty of Pharmacy, Charles University, Department of Pharmacology and Toxicology . Study Program. Pharmacology and Toxicology. Read more
 Supervisor: Prof P Nachtigal
 30 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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NIHR Leeds BRC: Pre-clinical evaluation of novel regenerative medicine strategies for knee osteoarthritis

University of Leeds Faculty of Medicine and Health
Historically, articular cartilage was considered incapable of spontaneous repair.  However, biomechanical correction in osteoarthritis (OA) using high tibial osteotomy or joint distraction demonstrated the remarkable joint to regeneration by “merely” correcting joint alignment. Read more
 Supervisors: Prof H Pandit, Prof D McGonagle
 26 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Using human pluripotent stem cell-based models to study glia-associated biology in neurological diseases

Masaryk University Faculty of Medicine
Affiliation. Masaryk University, Faculty of Medicine. Study program. Ph.D. program Biomedical Sciences. Specialization. Cell and Tissue Morphology. Read more
 Supervisor: Dr DB Bohačiaková
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Optogenetic sculpting of next-generation organoids for disease modelling of congenital malformations including spina bifida

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
The ability to generate human induced pluripotent stem cells (iPSC) from adult cell types has revolutionised regenerative medicine research. Read more
 Supervisors: Dr G Galea, Prof J Sowden
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Vascularising human mini-brains in a dish

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Blood vessels play a pivotal role in brain development and function. They promote tissue growth and survival by supplying nutrients and oxygen to surrounding tissues, signals to progenitor populations, as well as guiding neuronal migration. Read more
 Supervisors: Dr PA Alexandre, Prof D Long
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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A Patient-derived 3D humanized model of ADCY5-related disease to accelerate therapeutic approaches for patients

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
ADCY5-related disease is a genetic disorder caused by mutations in the ADCY5 gene, which encodes for the isoform 5 of adenylyl cyclase (ADCY5)1. Read more
 Supervisors: Dr S Barral, Dr M Kurian, Dr HZ Zhou
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Genomic actions of RAR and VDR ligands

Medical University of Vienna Institute for Pathophysiologie and Allergy
The Doctoral Candidate (DC) will determine whether the combination of RARγ antagonist and VDR agonist is suitable as a differentiation therapy against acute myeloid leukaemia (AML). Read more
 Supervisor: Prof E Marcinkowska
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Development of novel therapies for Hirschsprung’s Disease

University of Liverpool Faculty of Health and Life Science
As a PhD student, you'll be part of a groundbreaking project aiming to revolutionise the treatment landscape for Hirschsprung's Disease (HSCR). Read more
 Supervisors: Miss RH Harwood, Dr B Wilm, Miss SA Almond
 26 April 2024  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Eliminating Harmful Cells to Maintain Homeostatis and Prevent Tumorigenesis

Cardiff University Cardiff School of Biosciences
Hamaratoglu Lab studies cell-cell signalling in development, homeostasis and tumourigenesis. We take advantage of outstanding genetic tools in Drosophila, and use larval imaginal discs as model epithelial organs. Read more
 Supervisors: Dr F Hamaratoglu, Dr C Hogan
 8 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Obtaining insights into how a signalling hub protein Ras activates multiple effectors

University of Leicester Molecular and Cell Biology
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more
 Supervisors: Dr K Tanaka , Dr R Mahen
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Human Genetics, Genomics and Disease: Integrating fusion-proteins molecular signatures for advancing sarcoma diagnosis and therapy

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: MRC Human Genetics Unit
Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center, Berlin, Germany. Supervisors. Dr Nezha Benabdallah, Dr Daria Bunina. Read more
 Supervisor: Dr NB Benabdallah
 19 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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