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Biochemistry PhD Projects, Programs & Scholarships in the UK
We have 664 Biochemistry PhD Projects, Programs & Scholarships in the UK
We have 664 Biochemistry PhD Projects, Programs & Scholarships in the UK
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Understanding cellular receptors mediating signalling and viral infection - molecular mechanisms and development of new therapeutics
Cellular receptors initiate signalling pathways that regulate all aspects of cell behaviour and these receptors are key therapeutic targets for a wide range of diseases including cardiovascular disease and cancer. Read more
Understanding gene regulation by HDAC1 complexes in development and cancer
Packaging DNA into nucleosomes helps protect the long fragile genomes of eukaryotic species. However, in doing so it becomes an ever-present physical barrier to the machinery required for its replication, repair and transcription. Read more
Cell growth signalling in space: How does mTOR kinase communicate with diverse cellular compartments?
PROJECT IN BRIEF. This 4-year PhD project addresses the fundamental question of how individual cells sense and respond to environmental changes. Read more
Molecular microbiology of Mycobacterium tuberculosis and related Actinobacteria
M. tuberculosis causes tuberculosis, causing 1.5 million deaths per year. Other members of the Actinobacteria include the important human pathogens M. Read more
Cancer biology: identification of new treatment options for EML4-ALK driven lung cancer through understanding mechanisms of cell division and migration.
Lung cancer is the largest cause of cancer-related deaths in the UK and worldwide. While little progress has been made in long-term survival rates, we now have a good understanding of the genetic drivers raising the prospect of earlier diagnosis and more effective treatments. Read more
How do RNA-binding proteins control splice site selection? A multi-disciplinary approach.
Almost every protein-coding gene in vertebrates can and does express multiple proteins. This is achieved primarily by RNA splicing, which is an essential step in gene expression in mammals and generates incredible diversity. Read more
3D genome folding and its role in DNA-based processes
The organization of genomic DNA into chromatin fibres and nucleosomes and their regulation by histone modifications is well understood, as is the relevance of these mechanisms for gene regulation. Read more
Revealing epigenetic signaling mechanisms in genome regulation and cancer.
We are looking for highly motivated PhD students to join our efforts to reveal epigenetic mechanisms that regulate the function of eukaryotic genomes in health and disease. Read more
Targeting molecular mechanisms of fibrosis to develop new therapies.
Fibrosis is a common endpoint of chronic inflammatory disease and is therefore implicated in >40% of deaths in the developed world. Read more
Targeting senescence to ameliorate ageing and treat cancer and other age-related diseases
Ageing is a biological process that affects all humans. Despite the scientific advances of the past decades, the mechanisms that lead to ageing are not fully understood. Read more
Obtaining an integrated understanding of oncogenic RAS signalling
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more
Regulation of variant antigen gene expression in African trypanosomes
We investigate the molecular biology of African trypanosomes, with a particular focus on the epigenetic control of gene expression. Trypanosomes are… Read more
An investigation into an aspect of Science Education Research
There is an opportunity for an interested potential PhD student to engage in a project focused on an aspect of Science Education Research (SER). Read more
Cryptosporidium pathogenicity and virulence – the parasite, the host, and the microbiome
The virulence of a pathogen varies from infection to infection. Cryptosporidium causes more diarrheal disease in humans and livestock than any other pathogen. Read more
