Snails and slugs cause worldwide problems, both in terms of direct damage to crops, and as intermediate vectors for diseases of farm animals. Read more
This project is a collaboration between two research groups. Prof Skirmantas Kriaucionis research group aims to elucidate the molecular function of DNA modifications in normal cells, leading to the understanding of how defective pathways contribute to the neoplasia. Read more
As cancer cells divide their DNA accumulates new mutations, some of which will lead to the generation of neoantigens – mutant peptides that can be recognised by immune cells as non-self. Read more
Are you interested in AI as well as the brain? Then this interdisciplinary 4-year PhD studentship might be for you. we are looking for a bright and highly motivated student to utilise modern Artificial Intelligence (AI) algorithms to analyse images of the retina. Read more
It has become clear in recent years that bacterial pathogens, within their mammalian hosts, can enter a quiescent state where metabolism is partially switched… Read more
Cardiometabolic disorders such as coronary artery disease-(CAD), obesity, and type-2 diabetes (T2D) represent the top leading causes of mortality worldwide. Read more
PHD finger protein 6 (PHF6) is a protein, consisting of two atypical plant homeodomains (aPHD1/2) with nuclear and nucleolar localization sequences. Read more
Research Group:
Cybersecurity, Privacy and HCC Research Section
The overarching goal of the studentship is to determine how routinely collected, anonymised data on hospital wards can be effectively repurposed, transformed, and visualised to support decision-making for patient care management in hospitals. Read more
Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more
Brown adipose tissue is an enigmatic tissue that plays an important role in energy metabolism. The increasing prevalence of obesity-related disorders has led to a growing need for therapeutic strategies to reverse diet-induced weight gain. Read more
Mitochondrial inhibition is an important ‘OFF-target’ mechanism of drug-induced toxicity in the clinic, contributing to drug attrition in clinical trials and drug withdrawal following approval because of severe adverse events 1. Read more
Plants live in and respond to fluctuating environments around them. Importantly, many plant responses are not only driven by current environmental conditions, but show “memory” to conditions in the past. Read more
Research interests/description of main research theme. Background. Mesenchymal stromal fibroblasts have emerged as key mediators of the inflammatory response and drivers of localised inflammation. Read more
We reported that silencing the WNT receptor ROR2 results in protection from cartilage breakdown and rapid pain relief in a murine model of osteoarthritis and in chondrogenesis in vitro and in vivo with human osteoarthritic chondrocytes (Thorup et al. Read more
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