Biological Sciences PhD Projects, Programmes & Scholarships in the UK

We have 1,430 Biological Sciences PhD Projects, Programmes & Scholarships in the UK

Obtaining insights into how a signalling hub protein Ras activates multiple effectors

University of Leicester Molecular and Cell Biology

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more

Supervisors: Dr K Tanaka , Dr R Mahen

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Unlocking the Secrets of Genome Regulation through cryo-EM

University of Leicester Molecular and Cell Biology

Are you an ambitious spirit, ready to make breakthrough discoveries at the frontier of epigenetics? Dive deep into the fascinating world of eukaryotic genomes with us! . Read more

Supervisors: Dr T Schalch, Dr AC Chaplin

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Using measures of eye movements and EEG to understand effects of cognitive ageing on reading

University of Leicester School of Psychology and Vision Sciences

Healthy ageing is associated with reductions in visual and cognitive abilities that are required for many activities of daily life (e.g., reading, navigation, object-finding). Read more

Supervisors: Prof K Paterson, Dr A Pagán

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Molecular level understanding of Mycobacterium tuberculosis

University of Leicester Department of Respiratory Sciences

Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more

Supervisors: Dr H O'Hare, Dr N Garton

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Failures to detect language errors during older age: Evidence of cognitive decline?

University of Leicester School of Psychology and Vision Sciences

Healthy ageing is associated with well-recognised cognitive decline across multiple domains from age 50 onwards (e.g., working memory, processing speed). Read more

Supervisors: Dr V McGowan, Dr S Gunn

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Epigenetics of early human development: From molecular mechanisms to regenerative medicine

University of Leicester Molecular and Cell Biology

Ever wondered how nature maintains balance of gene expression between sex chromosomes? Well, the 46th chromosome of XX females, the second X, has to be switched off. Read more

Supervisors: Dr Y Markaki, Dr T Schalch

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Epigenetic ageing and calorie restriction in an insect model system

University of Leicester Department of Genetics and Genome Biology

This project will help establish an insect model for epigenetic ageing, by analysing the effects of calorie restriction on chronological and epigenetic aging in an important insect model, Nasonia vitripennis, extending our discovery of an epigenetic clock in Nasonia. . Read more

Supervisors: Prof E Mallon, Dr K Chen

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Understanding centrosome function in the human airway

University of Leicester Molecular and Cell Biology

Breathing sustains our life and is also important for our quality of life. Inside the lung, billions of hair-like structures called cilia beat a million times a day to promote a process called mucociliary clearance. Read more

Supervisors: Dr R Mahen, Prof EH Hollox

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Investigating the role of SUMOylation in meiotic recombination and chromosome segregation in Arabidopsis

University of Leicester Department of Genetics and Genome Biology

Post-translational modifications of proteins such as phosphorylation, methylation and acetylation have been extensively studied in eukaryotes and now the Small Ubiquitin modifier (SUMO) is gaining attention for its importance in fundamental biological roles. Read more

Supervisors: Dr J Higgins, Dr D Guttery

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Unlocking the genetic potential of barley by modulating recombination

University of Leicester Department of Genetics and Genome Biology

Barley is a major worldwide crop used for malting and animal feed. However, breeding new varieties is constrained by the frequency of genetic crossovers (1-3 crossovers per chromosome pair) and their distribution (biased towards the chromosome ends) that underpin crop improvement1,2. Read more

Supervisors: Dr J Higgins, Dr D Guttery

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Enhancing meiotic recombination in wheat by modulating RECQ helicases

University of Leicester Department of Genetics and Genome Biology

Wheat accounts for 20% of the calories and protein consumed by humans and is the largest crop in the UK, but yields have plateaued and are susceptible to decline due to extreme weather conditions. Read more

Supervisors: Dr J Higgins, Dr D Guttery

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health

We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more

Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Dissecting the interplay of extracellular vesicle signalling and tryptophan metabolism in schizophrenia pathogenesis

University of Leicester Department of Genetics and Genome Biology

L-kynurenine (KYN) and kynurenic acid (KYNA) are metabolites of the kynurenine pathway (KP) of tryptophan degradation and have been found to be increased in the brains of patients with schizophrenia. Read more

Supervisor: Prof F Giorgini

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Understanding the roles of triacylglycerol in modulating mycobacterial growth and biophysical properties

University of Leicester Department of Respiratory Sciences

Mycobacteria contain more lipid than any other bacteria. In addition to a characteristically lipid-rich cell envelope, mycobacteria can accumulate triacylglycerol (TAG) as cytoplasmic lipid bodies (LBs). Read more

Supervisors: Dr N Garton , Dr G Mukamolova

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Supervisors: Dr JF Fox, Dr JH Hodgkinson

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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We have 1,430 Biological Sciences PhD Projects, Programmes & Scholarships in the UK

Biological Sciences PhD Projects, Programmes & Scholarships in the UK

We have 1,430 Biological Sciences PhD Projects, Programmes & Scholarships in the UK

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