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Cancer Biology PhD Projects, Programmes & Scholarships in the UK
We have 220 Cancer Biology PhD Projects, Programmes & Scholarships in the UK
We have 220 Cancer Biology PhD Projects, Programmes & Scholarships in the UK
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mRNA epigenetics: Charaterization of a novel layer of gene regulation for essential brain functions
Research Group:
BBSRC MIBTP
For over 40 years we know about modified nucleotides in mRNA, but the functions for these essential modifications are largely elusive. Read more
Defining the transcription roles of BRCA1 and BRCA2
BRCA1 and BRCA2 mutations predispose to both breast and ovarian cancers, with both factors playing many crucial roles in DNA damage repair and response. Read more
Coordination between RNAPII transcription and DNA replication
RNA Pol II (RNAPII) transcription and DNA replication are the two essential-for-life processes that use as a substrate the DNA in our cells, allowing the¬¬m to express the content of their genetic information and to propagate these instructions to daughter cells. Read more
BBSRC MIBTP - Identification of pathways deregulating neuronal ELAV/Hu RNA binding proteins and alternative splicing in neurodegeneration
Research Group:
BBSRC MIBTP
ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions. Read more
RNA Interference for Glioblastoma therapy using lipid nanoparticles
University of Central Lancashire Funded Doctoral Training Centre for Industry Collaboration. Inaugural PhD Studentships. The successful applicant will receive an annual stipend payment of £16062 and tuition fees will be covered. Read more
Functional characterisation of Siglec-15 as a new checkpoint inhibitor target
Tumours evolve many ways to gain survival advantage. New blood vessels are formed to deliver extra oxygen, nutrients and to assist mobilisation of… Read more
An interdisciplinary approach to tackling the problem of late Myeloma diagnosis.
There are two parallel studentships on offer. One (this project) is a wet lab project and the other is a bioinformatics project. Both are addressing the fact that multiple myeloma (MM) (a blood cancer of antibody producing cells) is nearly always diagnosed late. Read more
Role of RNA-DNA hybrids and transcription-replication conflicts in colorectal cancer
Replication stress, or replication-associated DNA damage, occurs frequently in cancer. There is a growing interest in targeting oncogene-induced replication stress for cancer therapy. Read more
Exploiting metabolic vulnerabilities induced by dietary restriction as novel therapies for infant leukaemia
TO APPLY, CLICK 'INSTITUTION WEBSITE'. Infant leukaemia is an aggressive malignancy with cure rates of less than 50%. Importantly, despite large international trials, there has been no improvement in survival over the last 2 decades. Read more
Differential growth factor pathways in mesothelioma subtypes
TO APPLY CLICK 'INSTITUTION WEBSITE' . The genetic landscape of mesothelioma is dominated by loss of function mutations in various tumour suppressor genes (eg. Read more
Investigating the Role of Tertiary Lymphoid Structures in Tumour-Mediated Immunosuppression in pancreaticobiliary cancer employing spatial biology characterisation
TO APPLY CLICK 'INSTITUTION WEBSITE' . PDAC has one of the worst outcomes of any cancer, with a 5-year survival of less than 5%. Read more
Development of cellular and tissue segmentation algorithms within the digital pathology platform QuPath for accurate assessment of mIF across a breadth of solid tumours
TO APPLY CLICK 'INSTITUTION WEBSITE' . Recent years have seen a revolution in our ability to generate high-resolution microscopic images of tumour tissue to reveal gene activity in single cells. Read more
Understanding the role of IKK in the tumour microenvironment and establishing it as a novel therapeutic target in colorectal cancer
TO APPLY CLICK 'INSTITUTION WEBSITE' . Colorectal cancer (CRC) remains the 2nd most common cancer and 3rd most common cause of cancer-related death globally. Read more
Understanding the pro- and anti-tumour functions of IFNγ-producing γδ T cells
TO APPLY CLICK 'INSTITUTION WEBSITE' . γδ T cells are a rare population of T cell receptor-expressing cells that function like innate immune cells.γδ T cells consist of several different subtypes that can promote or prevent cancer progression, depending on the cytokines and cytotoxic molecules they express. Read more
Elucidating the role of primary and secondary senescence in liver cancer
TO APPLY CLICK 'INSTITUTION WEBSITE' . Senescence is a cell cycle arrest state characterised by a pro-tumorigenic secretome. Read more