Cancer Biology PhD Projects, Programmes & Scholarships in the UK

Unraveling the Impact of Epigenetic and Microenvironmental Factors on Breast Cancer Development and Progression

University of York York Biomedical Research Institute

Breast cancer is a complex disease with multifaceted aetiology, and understanding the processes that regulate disease development and progression is crucial for improving diagnostics and treatment strategies. Read more

Supervisors: Dr AN Holding, Dr W Brackenbury

Year round applications PhD Research Project Self-Funded PhD Students Only

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Studying protein homeostasis in healthy and malignant stem cells

University of York York Biomedical Research Institute

This PhD will focus on studying the protein biology of healthy and malignant stem cells of the blood system. Read more

Supervisors: Dr W Grey, Prof D G Kent

Year round applications PhD Research Project Self-Funded PhD Students Only

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Short and long-distance communication in cancer: Feedback regulation of Ras signalling in tumourigenesis and cachexia

Cardiff University Cardiff School of Biosciences

Hamaratoglu Lab studies cell-cell signalling in development and tumourigenesis. We take advantage of outstanding genetic tools in Drosophila, and use larval imaginal discs as model epithelial organs. Read more

Supervisors: Dr F Hamaratoglu, Dr C Hogan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Designing and evaluating novel nanotherapeutics to enhance the effectiveness of radiotherapy in the treatment of solid cancers.

Queen’s University Belfast School of Pharmacy

One in two cancer patients will receive radiotherapy as part of their treatment. For patients with a localised cancer diagnosis effective radiotherapy represents the best chance of a curative outcome, however, is not without risk. Read more

Supervisor: Dr J Coulter

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural investigation of oncogenic splicing factors

University of Leicester Molecular and Cell Biology

More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more

Supervisors: Dr C Dominguez, Prof I Eperon, Prof A Hudson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Obtaining an integrated understanding of oncogenic RAS signalling

University of Leicester Molecular and Cell Biology

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more

Supervisor: Dr K Tanaka

Year round applications PhD Research Project Self-Funded PhD Students Only

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Developing novel targeted therapeutic approaches through induced-proximity of proteins

University of Dundee School of Life Sciences

Protein post-translational code is at the heart of protein function and signal transduction in cells. Enzymes catalyse the addition or removal of post-translational modifications (PTM), such as phosphorylation, methylation, acetylation, and ubiquitylation, on proteins. Read more

Supervisors: Prof G Sapkota, Prof A Ciulli

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Cancer: Investigation of accentuated mitochondrial ROS and NLRP3 inflammasome activation in cystic fibrosis and colorectal carcinoma.

University of Leeds Faculty of Medicine and Health

Cystic fibrosis (CF) is associated with an accentuated inflammatory response to bacterial lipopolysaccharides (LPS), increased resting energy expenditure and a higher than expected prevalence of gastrointestinal and other malignancies. Read more

Supervisors: Prof D Peckham, Prof D Jayne, Dr S Savic, Miss LR Caley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

University of Leeds Faculty of Medicine and Health

The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more

Supervisors: Dr G Mavria, Dr S Bell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Deconvoluting the spatial multi-omic landscape of high-grade glioma to target post-surgical residual disease

University of Sheffield School of Medicine and Population Health

Background. High-grade gliomas are the most common cancers arising within the brain and contribute to ~190,000 brain tumour related deaths/year globally. Read more

Supervisors: Dr S Collis, Dr O Rominiyi, Dr M Dunning

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating molecular drivers of cell invasion

King’s College London Division of Cancer Studies

The Wells laboratory focusses on exploring the molecular mechanisms that underlie cell invasion. We have interests in cancer cell invasion and hemopoietic cell invasion. Read more

Supervisor: Prof C Wells

Year round applications PhD Research Project Awaiting Funding Decision/Possible External Funding

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Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more

Supervisor: Dr T You

1 August 2024 PhD Research Project Self-Funded PhD Students Only

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Development and validation of a radiosensitivity gene expression signature in prostate cancer

The University of Manchester Faculty of Biology, Medicine and Health

Prostate cancer (PCa) is diagnosed in 1.4 million men globally each year and causes 375,000 deaths, making PCa the second most common cancer and fifth most common cause of death from cancer in men[1]. Read more

Supervisors: Prof A Choudhury, Dr MR Reardon, Dr TS Smith

Year round applications PhD Research Project Self-Funded PhD Students Only

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Mining the Hippo signalling pathway for novel anti-cancer therapeutics

Kingston University Faculty of Health, Science, Social Care and Education

Candidates are invited to join the Kadri Lab, where our research focuses on developing innovative chemical approaches for discovering novel therapeutics to address unmet global health needs. Read more

Supervisor: Dr H Kadri

Year round applications PhD Research Project Self-Funded PhD Students Only

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Curing disease: using natural or novel compounds to target key signalling pathways

Kingston University Faculty of Health, Science, Social Care and Education

The role of signalling pathways in the initiation and progression of disease is an extensively studied but not clearly understood field. Read more

Supervisor: Dr A Elbediwy

Year round applications PhD Research Project Self-Funded PhD Students Only

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Evaluating the role of immune microenvironment on cancer progression using spatial and imaging approaches

King’s College London School of Cancer and Pharmaceutical Sciences

Talented and motivated students, passionate about doing research and advancing cancer research, are invited to apply for this PhD position. Read more

Supervisor: Dr H Sailem

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Cell-matrix interface engineering for regenerative medicine applications and disease modelling

The University of Manchester Faculty of Biology, Medicine and Health

Dr. Mahetab Amer is seeking motivated students with backgrounds in tissue engineering, cell biology, materials science, or related fields to join her dynamic, multidisciplinary research group at the Division of Cell Matrix Biology and Regenerative Medicine, University of Manchester. Read more

Supervisor: Dr M.A Amer

Year round applications PhD Research Project Self-Funded PhD Students Only

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MRes in Clinical Science

University of East Anglia Norwich Medical School

Our MRes Clinical Science is your chance to experience the reality of cutting-edge clinical or biomedical research. You’ll develop a broader, more considered approach to a specific area of medical research, gaining expertise in the intellectual and practical skills of scientific research in the process. Read more

Supervisor: Dr K Tyler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Improvements of asparaginase-based treatment for Childhood ALL

Cardiff University Cardiff School of Biosciences

Project Description. Most popular current treatments for childhood acute lymphoblastic leukaemia (ALL) in clinic are based on asparaginase (Raja et al 2012). Read more

Supervisors: Dr O V Gerasimenko, Dr J Gerasimenko

Year round applications PhD Research Project Self-Funded PhD Students Only

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Driving phenotypic plasticity and metastasis in small cell lung cancer

The University of Manchester Faculty of Biology, Medicine and Health

Small cell lung cancer (SCLC) is an aggressive malignancy with poor prognosis. Underlying this aggressiveness is intra-tumoural heterogeneity driven by phenotypic plasticity wherein tumour cells transition from a neuroendocrine (NE) to a non-neuroendocrine (non-NE) phenotype. Read more

Supervisors: Prof A Malliri, Dr K Simpson, Prof C Dive

Year round applications PhD Research Project Self-Funded PhD Students Only

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Inducing ferroptotic death to kill cancer cells

The University of Manchester Faculty of Biology, Medicine and Health

Ferroptosis is an iron-dependent form of regulated necrotic cell death triggered by oxidative degradation of lipids in membrane bilayers and subsequent irreparable damages to the plasma membrane (1). Read more

Supervisors: Dr C Tournier, Dr K Finegan

Year round applications PhD Research Project Self-Funded PhD Students Only

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A sticky situation; determining the interplay between gastric mucus and the gastric microbiota using pre-cancerous organoids

University of Birmingham Institute of Microbiology and Infection

The gastrointestinal tract is lined by a layer of mucus, which serves as a barrier separating the microbiota and the underlying epithelial cell layer (Paone and Cani, 2020). Read more

Supervisors: Dr A Rossiter, Dr L Crouch

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting senescence to ameliorate ageing and treat cancer and other age-related diseases

University of Leicester Molecular and Cell Biology

Ageing is a biological process that affects all humans. Despite the scientific advances of the past decades, the mechanisms that lead to ageing are not fully understood. Read more

Supervisor: Prof S Macip

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer biology: identification of new treatment options for EML4-ALK driven lung cancer through understanding mechanisms of cell division and migration.

University of Leicester Molecular and Cell Biology

Lung cancer is the largest cause of cancer-related deaths in the UK and worldwide. While little progress has been made in long-term survival rates, we now have a good understanding of the genetic drivers raising the prospect of earlier diagnosis and more effective treatments. Read more

Supervisor: Prof A Fry

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the link between fibrosis, inflammation, and breast cancer initiation

University of Leicester Molecular and Cell Biology

Understanding the fundamental molecular events that result in tumour initiation is critical to the prevention and treatment of human cancers. Read more

Supervisor: Dr C Switzer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding gene regulation by HDAC1 complexes in development and cancer

University of Leicester Molecular and Cell Biology

Packaging DNA into nucleosomes helps protect the long fragile genomes of eukaryotic species. However, in doing so it becomes an ever-present physical barrier to the machinery required for its replication, repair and transcription. Read more

Supervisor: Prof S Cowley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding centrosome assembly in healthy and cancerous tissue with imaging

University of Leicester Molecular and Cell Biology

This is an opportunity for a scientist to join the lab of Dr Robert Mahen in the Department of Molecular & Cell Biology at the University of Leicester. Read more

Supervisor: Dr R Mahen

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating WSB-1 as a prognostic marker and therapeutic target in urogenital cancers

The University of Manchester Faculty of Biology, Medicine and Health

Prostate cancer (PCa) is the commonest cancer diagnosed in men, with 5-year survival rates of 60% in those with advanced disease. Read more

Supervisors: Dr IP Monteiro dos Santos Pires, Prof AC Choudhury

Year round applications PhD Research Project Self-Funded PhD Students Only

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Estimating the global cancer burden due to low levels of physical activity

University of Bristol Bristol Medical School

Rationale. Around 40% of all cancers are thought to be avoidable by modification of lifestyle factors. Obesity has been found to be a risk factor for several cancers and was estimated to have caused around 3.6% of all new cancers which occurred in 2012. Read more

Supervisors: Dr S Lewis, Prof R Martin, Dr R Pulsford, Prof R Jago, Dr FB Bray

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Identifying DNA methylation signatures of prostate cancer progression and mortality among patients with clinically confirmed, localised disease at baseline in a large prospective clinical trial

University of Bristol Bristol Medical School

Rationale. Prostate Cancer (PCa) is a leading cause of male mortality, with 336,000 deaths worldwide each year (1). Although most PCa cases are indolent, slow-growing, and tend not to progress, a subset of PCa cases are more aggressive and will progress to metastases, treatment resistance and death. Read more

Supervisors: Dr P Yousefi, Prof R Martin, Dr M Suderman, Dr A Lane, Dr SM Merriel

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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We have 242 Cancer Biology PhD Projects, Programmes & Scholarships in the UK

Cancer Biology PhD Projects, Programmes & Scholarships in the UK

We have 242 Cancer Biology PhD Projects, Programmes & Scholarships in the UK

Unraveling the Impact of Epigenetic and Microenvironmental Factors on Breast Cancer Development and Progression

Studying protein homeostasis in healthy and malignant stem cells

Short and long-distance communication in cancer: Feedback regulation of Ras signalling in tumourigenesis and cachexia

Designing and evaluating novel nanotherapeutics to enhance the effectiveness of radiotherapy in the treatment of solid cancers.

Structural investigation of oncogenic splicing factors

Obtaining an integrated understanding of oncogenic RAS signalling

Developing novel targeted therapeutic approaches through induced-proximity of proteins

Cancer: Investigation of accentuated mitochondrial ROS and NLRP3 inflammasome activation in cystic fibrosis and colorectal carcinoma.

Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

Deconvoluting the spatial multi-omic landscape of high-grade glioma to target post-surgical residual disease

Investigating molecular drivers of cell invasion

Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

Development and validation of a radiosensitivity gene expression signature in prostate cancer

Mining the Hippo signalling pathway for novel anti-cancer therapeutics

Curing disease: using natural or novel compounds to target key signalling pathways

Evaluating the role of immune microenvironment on cancer progression using spatial and imaging approaches

Cell-matrix interface engineering for regenerative medicine applications and disease modelling

MRes in Clinical Science

Improvements of asparaginase-based treatment for Childhood ALL

Driving phenotypic plasticity and metastasis in small cell lung cancer

Inducing ferroptotic death to kill cancer cells

A sticky situation; determining the interplay between gastric mucus and the gastric microbiota using pre-cancerous organoids

Targeting senescence to ameliorate ageing and treat cancer and other age-related diseases

Cancer biology: identification of new treatment options for EML4-ALK driven lung cancer through understanding mechanisms of cell division and migration.

Understanding the link between fibrosis, inflammation, and breast cancer initiation

Understanding gene regulation by HDAC1 complexes in development and cancer

Understanding centrosome assembly in healthy and cancerous tissue with imaging

Investigating WSB-1 as a prognostic marker and therapeutic target in urogenital cancers

Estimating the global cancer burden due to low levels of physical activity

Identifying DNA methylation signatures of prostate cancer progression and mortality among patients with clinically confirmed, localised disease at baseline in a large prospective clinical trial

We have 242 Cancer Biology PhD Projects, Programmes & Scholarships in the UK

Cancer Biology PhD Projects, Programmes & Scholarships in the UK

We have 242 Cancer Biology PhD Projects, Programmes & Scholarships in the UK

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