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Endocrinology PhD Projects, Programs & Scholarships in the UK

We have 46 Endocrinology PhD Projects, Programs & Scholarships in the UK

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Showing 1 to 30 of 46
  Investigating Therapeutic Effect of Different Antioxidants in Friedreich’s Ataxia (FRDA)
  Dr S Anjomani-Virmouni
Applications accepted all year round

Funding Type

PhD Type

Friedreich’s ataxia (FRDA) is an inherited neurodegenerative disorder caused by epigenetic silencing of the frataxin gene. It is the most common inherited ataxia, affecting 1:50,000 Caucasians, and is characterised by neurodegeneration, cardiomyopathy, diabetes mellitus and skeletal deformities.
  Heat adaptation in older/elderly individuals
  Dr O Gibson
Applications accepted all year round

Funding Type

PhD Type

Whilst traditionally heat adaptation has been a priority for athletes and occupational workers ahead of exposure to hot/hot-humid environments, forecast increases in the frequency and intensity of heat waves as a result of climate change means the general public is likely to be exposed to extreme environments as part of their daily life.
  Reducing sedentary behaviour and increasing physical activity for the prevention and management of Type 2 diabetes
  Dr D Bailey
Applications accepted all year round

Funding Type

PhD Type

This proposed research will follow a process of intervention development and evaluation targeted at reducing and breaking up sitting time for the prevention and/or management of Type 2 diabetes.
  Beta cell regeneration for diabetes therapy
  Dr N Hill
Applications accepted all year round

Funding Type

PhD Type

Stem cells hold great potential for the creation of artifical insulin-producing beta cells to treat diabetes. Matrix and matricellular components play a critical role in supporting the differentiation of stem cells into mature, functional beta cells.
  Exercise and nutritional status on metabolic factors, hormonal responses and inflammation in women
  Dr J Allgrove
Applications accepted all year round

Funding Type

PhD Type

Obesity is a major risk factor for chronic diseases such as type 2 diabetes, adverse cardiovascular events and metabolic syndrome-related disorders.
  Investigating metabolic changes in neurodegeneration
  Dr F Mackenzie, Dr M Stolinski
Applications accepted all year round

Funding Type

PhD Type

This 3-year PhD will study the increasingly recognised association between metabolic disease and neurodegeneration using in vitro cell culture methods.
  Role of telomere attrition in cardiometabolic disease risk
  Dr J Buxton, Dr N Hill
Applications accepted all year round

Funding Type

PhD Type

Common conditions such as Type 2 diabetes (T2D) and coronary artery disease (CAD) are complex disorders caused by a myriad of interacting genetic and lifestyle factors.
  The role of matrix interactions in regulating the SPARC family of matricellular proteins.
  Dr N Hill, Dr A Munasinghe
Applications accepted all year round

Funding Type

PhD Type

The SPARC family of matricellular proteins determine the way in which cells respond to their extracellular environment. SPARC family proteins interact with a range of binding partners, including matrix proteins (1).
  Sex differences in association between sleep loss and energy metabolism; implications for lifestyle modifications (Ref: SF20/SER/MCIVER)
  Dr V McIver
Applications accepted all year round

Funding Type

PhD Type

The incidence of reduced sleep in the UK is increasing. A report from the Sleep Council has shown that despite a recommendation of 7-9 hours of sleep per night, 74% of individuals sleep less than 7 hours (The Sleep Council, 2017).
  Cellular protein quality control in diabetes-associated heart disease: The insight into mechanisms and therapeutic potentials
  Dr V Liu, Dr L Swanton
Applications accepted all year round

Funding Type

PhD Type

Cardiovascular complications are the leading causes of diabetes mortality. With the exception of vascular and valvular injuries, diabetic cardiomyopathy (DCM) is a distinct myocardial disease, which is characterised by abnormal cellular metabolism and defects in organelles function, leading to impaired cardiac function.
  Impact of liver reduction diet, low calorie diet and bariatric surgery on hepatic health and cardiometabolic risk factors.
  Dr H Soran, Dr A Syed, Dr R Donn, Dr M Ferdousi
Applications accepted all year round

Funding Type

PhD Type

Obesity and its related co-morbidities, especially Type 2 Diabetes (T2DM), are a major source of disability and premature mortality from micro- and macro-vascular discease.
  Small nerve fibre damage and sexual dysfunction in diabetes and obesity. A mechanistic assessment and effect of lipid modifying agents.
  Dr H Soran, Prof R Malik, Dr R Donn, Dr M Ferdousi
Applications accepted all year round

Funding Type

PhD Type

Diabetes and its complications represent a growing global health burden, affecting an estimated 366 million people worldwide.
  Investigating the mechanisms contributing to placental dysfunction in pregnancies complicated by diabetes: role of the hexosamine biosynthetic pathway
  Prof M Westwood, Prof J Aplin, Dr J Myers
Applications accepted all year round

Funding Type

PhD Type

Maternal diabetes is a major risk factor for fetal overgrowth, which is associated with poor outcomes including stillbirth, neonatal morbidity and increased risk of diabetes in adulthood.
  Control of Parathyroid Hormone Secretion
  Dr D Ward, Dr J Bruce
Applications accepted all year round

Funding Type

PhD Type

The regulation of parathyroid hormone (PTH) secretion is of fundamental importance for calcium homeostasis and in mineral conditions affecting bone and the kidneys.
  Lateral hypothalamus as a visual centre controlling arousal, autonomic function and reflex behaviours
  Dr T Brown, Dr D Bechtold
Applications accepted all year round

Funding Type

PhD Type

In addition to supporting our conscious perception of the world around us, light and visual stimuli exert wide ranging effects on animal physiology and behaviour via hard-wired ‘reflexes’ which range from simple effects of light on sleep, alertness and neuroendocrine function to the avoidance of rapidly approaching objects.
  Rhythmic control of energy balance - to understand how our internal clocks regulate energy metabolism
  Dr D Bechtold, Prof D Ray
Applications accepted all year round

Funding Type

PhD Type

24-hour rhythms are present in virtually all aspects of our behaviour and physiology. These rhythms are underpinned by circadian clocks that run throughout the body, and act within each tissue to orchestrate many organ functions and rhythmic activities (e.g.
  Building the human endometrium in vitro: The role of macrophages in receptive and decidual endometrium to optimise reproductive health
  Dr E Mann, Dr Peter Ruane, Prof J Aplin, Dr L Mohiyiddeen
Applications accepted all year round

Funding Type

PhD Type

The human endometrium is a highly dynamic tissue that rapidly generates over ~20 days and differentiates to form a uterus lining receptive to embryo implantation, further transforming into decidua to support embryonic development, or breaking down before regenerating a few days later.
  Computer-aided Detection of Osteoporotic Vertebral Fractures in Clinical Images Using Convolutional Neural Network Constrained Local Models (CNN-CLMs)
  Dr P Bromiley, Prof T Cootes, Dr EP Kariki
Applications accepted all year round

Funding Type

PhD Type

Osteoporosis is a common, degenerative skeletal disorder that increases the risk of fractures and causes significant morbidity and mortality.
  Is there a switch between prostamides and prostaglandins in women with dysmenorrhoea and heavy menstrual bleeding?
  Prof K Marshall, Dr D Fischer, Prof A Nicolaou
Applications accepted all year round

Funding Type

PhD Type

Dysmenorrhoea, painful menstrual cramps, and heavy menstrual bleeding are common debilitating symptoms in women with or without an underlying pelvic pathology.
  The role of the microenvironment in regulating breast cancer metastatic colonisation
  Dr R Clarke, Dr Ciara O'Brien, Dr R Eyre
Applications accepted all year round

Funding Type

PhD Type

The metastatic spread of breast cancer cells and their colonisation of important organs is the cause of death in 95% of breast cancer.
  Interrogating the role of retriever sorting complex in adipose insulin-sensitivity and GLUT4 recycling
  Dr P Whitley
Applications accepted all year round

Funding Type

PhD Type

The University of Bath is inviting applications from self-funded applicants for the following PhD opportunity. Supervisors. Dr Paul Whitley, Department of Biology & Biochemistry https://researchportal.bath.ac.uk/en/persons/paul-whitley.
  Establishing a rationale for FGF23 modulation as a therapy in the critically ill patient
  Dr D Parekh, Prof D Thickett, Dr A Scott
Application Deadline: 1 September 2020

Funding Type

PhD Type

Research interests/description of main research theme. Everyone suffers at least one critical illness during their life. In the UK, 160,000 critically ill patients are admitted annually to intensive care units (ICU).
  Biomarkers of Genotoxic and Reprotoxic Effects after chemical exposure in vitro in human cells
  Research Group: Chemistry and Biosciences
  Prof D Anderson, Dr M Najafzadeh
Applications accepted all year round

Funding Type

PhD Type

In human monitoring procedures, measurements obtained from endpoints to determine genetic damage are sometimes referred to as biomarkers.
  Health Opportunity for Patient Empowerment in Gestational Diabetes (HOPE-GDM)
  Research Group: Chemistry and Biosciences
  Prof A M Graham, Prof R Qahwaji, Prof A Locke
Applications accepted all year round

Funding Type

PhD Type

Gestational Diabetes is a temporary condition diagnosed at 24-28 weeks gestation, where the body is unable to maintain normal blood glucose levels due to insulin resistance during pregnancy.
  Improving access to diabetes testing in the community. (EnglishEU19SF)
  Dr E English, Prof J Wain
Application Deadline: 31 May 2020

Funding Type

PhD Type

Diabetes is a major global health burden and is the 7th leading cause of death worldwide. Early identification and treatment of the disease has been shown to reduce the rate of complications.
  Precision Medicine DTP: Data-driven personalised care for Gestational Diabetes
  Research Group: Centre for Cardiovascular Science
  Prof R Reynolds, Dr D Wake, Dr A Manataki, Dr R Lindsay
Application Deadline: 1 June 2020

Funding Type

PhD Type

16% of women in the UK develop high levels of sugar in their blood during pregnancy (gestational diabetes (GDM)) and rates are increasing due to rising obesity levels among women.
  Global burden and determinants of hypoglycaemia: epidemiological analyses of the Hypoglycaemia Assessment Tool (HAT) study
  Dr F Zaccardi, Prof K Khunti
Application Deadline: 31 May 2020

Funding Type

PhD Type

Intensive glucose control results in higher rates of hypoglycaemia which negatively impacts the quality of life and prevents maintenance of a good glycaemic control.
  Exploring the role of meiotic proteins in cancer
  Dr U McClurg
Applications accepted all year round

Funding Type

PhD Type

Cancer is one of the main causes of death worldwide. The main challenge is the development of treatments specifically targeting cancers without killing healthy cells.
  EPSRC Centre for Doctoral Training in Sustainable Approaches to Biomedical Science: Responsible and Reproducible Research - SABS

Funding Type

PhD Type

Good degree in the Physical or Life Sciences? Interested in biological or medical research? We offer fully-funded PhD places across the Oxford Doctoral Training Centre programmes.
  Academic Endocrine Unit: investigating the molecular basis of endocrine and metabolic disorders that principally affect calcium and phosphate homeostasis.
  Prof R Thakker, Dr K Lines, Dr M Stevenson, Dr K Kooblall
Application Deadline: 24 July 2020

Funding Type

PhD Type

Other Potential Supervisors. Dr Asha Bayliss. The Academic Endocrine Unit investigates the molecular basis of endocrine and metabolic disorders that principally affect calcium and phosphate homeostasis.
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