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We have 81 Human Genetics PhD Projects, Programmes & Scholarships for European Students (exc UK) in the UK



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Human Genetics PhD Projects, Programmes & Scholarships for European Students (exc UK) in the UK

We have 81 Human Genetics PhD Projects, Programmes & Scholarships for European Students (exc UK) in the UK

A PhD in Human Genetics would provide you with the time and resources to conduct a research project into Human genes. A subcategory of Genetics, Human Genetics focuses only on coding DNA, known as genes, in Humans. This could involve studying inheritance, identifying genes involved in disease or developing novel therapeutics that target gene expression. These projects are predominantly laboratory-based.

What’s it like to do a PhD in Human Genetics?

As a Human Genetics PhD student, you’ll develop a wide range of skills in and out of the laboratory, from having the technical ability to perform gel electrophoresis and western blots to polymerase chain reaction (PCR). Out of the laboratory, you’ll have excellent time management to plan your experiments, which can often span several days, and you’ll have gained a wide range of subject knowledge from reading the literature surrounding your speciality.

Some typical research topics in Human Genetics include:

  • Investigating novel genetic links to diseases such as atherosclerosis
  • Developing improved methods of assessing genetic risk for disease screening
  • Researching the possibility of mRNA treatments
  • Studying the genetics of inherited conditions
  • Investigating gene regulation e.g. during an immune challenge

The majority of Human Genetics programmes are advertised projects with the scope of the project determined by the supervisor. Many of these come with attached funding, while a few ask you to find your own funding, which can be challenging as you’ll need to cover PhD and bench fees. The difficulty self-funding also makes proposing your own project uncommon in Human Genetics.

Day-to-day you’ll be in the laboratory conducting experiments, puzzling over data and analysing it using techniques from Bioinformatics and you’ll speak to your colleagues and supervisor about your current and future work.

To be awarded your PhD you must complete a thesis of about 60,000 words that contributes to the knowledge of your field and be able to defend it during your viva exam.

Entry requirements

The entry requirements for most Human Genetics PhD programmes involve a Masters in a subject directly related to Biology, with at least a Merit or Distinction. If English isn’t your first language, you’ll also need to show that you have the right level of language proficiency.

PhD in Human Genetics funding options

The research council responsible for funding Human Genetics PhDs in the UK is the Biotechnology and Biological Sciences Research Council (BBSRC). They provide fully-funded studentships including a stipend for living costs, a consumables budget for bench fees and a tuition fee waiver. Students don’t apply directly to the BBSRC, you apply for advertised projects with this funding attached.

It’s less common for Human Genetics PhD students to be ‘self-funded’ due to the additional bench fees. However, if you were planning to fund yourself it might be achievable (depending on your project) through the UK government’s PhD loan and part-time work.

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Advancing gender and sex equity in health research

There are health disparities within sex and gender. This project will explore the sex and gender differences in healthcare research to better understand how key areas of inequity impact on health outcomes. Read more

BBSRC NLD Doctoral Training Partnership: Deciphering the role of transcriptional enhancers in developmental gene regulation

Healthy cartilage in our joints is essential for us to maintain an active life into old age, with cartilage breakdown causing chronic pain, joint stiffness and reduced mobility. Chondrocytes, the only cell type present in cartilage, have a specialised phenotype that is initiated during development and then maintained throughout our lives. Read more

BBSRC NLD Doctoral Training Partnership: Lightsheet microscopy to uncover the architecture of gene regulation in human cells and its role in cancer

This BBSRC studentship provides a rare opportunity to work across disciplines - combining molecular biology and biophysics – to generate new insight into the fundamental biology of gene regulation, as well as a new approach to cancer biology. Read more

(Boots CTP) Development of Next Generation Peptide Location Fingerprinting for Enhanced Characterisation of Skin Ageing and Repair.

In skin, long-lived extracellular matrix (ECM) components in the dermis, and at the dermal-epidermal junction (DEJ) basement membrane, undergo a form of ageing where damage is gradually accumulated to their protein structures by mechanisms such as photo-oxidation (by ultraviolet radiation from the sun) and protease cleavage, leading to profound changes in tissue architecture and function. Read more

Exploring the function of protective genes and pathways in mitochondrial disease (Ref: RDF24/HLS/APP/WINTER)

Why study the basis of mitochondrial dysfunction in human disease? Mitochondria are vital cellular organelles that harness the process of oxidative phosphorylation (OXPHOS) to provide a useable energy source for the cell and body. Read more

Development of a novel polymer-based receptor for monitoring of BRCA genes

While most cancers are sporadic, some cancer types are associated with increased risk of heritability. These include prostate, breast, ovarian, and colorectal cancer, which in some cases may develop due to inheritance of cancer-susceptibility genes such as BRCA1 and BRCA2. Read more

MRC DiMeN Doctoral Training Partnership: Cardiovascular function around the clock: harnessing protective circadian mechanisms towards smarter design of novel therapies and interventions

Optimal cardiovascular function is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

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