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Immunology PhD Projects, Programs & Scholarships in the UK

We have 149 Immunology PhD Projects, Programs & Scholarships in the UK

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Showing 1 to 30 of 149
  Extracellular Vesicles – defining the functional surface proteome of vesicles
  Prof A Devitt, Dr D Aubert, Dr A Goddard
Application Deadline: 7 June 2020

Funding Type

PhD Type

Extracellular Vesicles (EV) are an exciting and novel mode of intercellular communication and they are known to have profound effects on recipient cells.
  The development of a cost-effective and stable single-administration vaccine (SAV) formulation to achieve vaccination regimen reduction
  Dr A Al-Khattawi
Application Deadline: 7 June 2020

Funding Type

PhD Type

Vaccination has greatly reduced the burden of infectious diseases worldwide. However, many vaccines e.g. for DTP and Polio require repeated administration over months to achieve effective immunity.
  Defining Mycobacterium tuberculosis in lung tissue – a novel discovery platform for new vaccine and drug targets
  Dr S Waddell, Dr J Salguero, Dr S Sharpe, Dr A Rawkins
Application Deadline: 29 June 2020

Funding Type

PhD Type

Applications are invited for a 3-year PhD studentship to join our tuberculosis research group in the Department of Global Health and Infection at Brighton and Sussex Medical School (BSMS).
  Developing new antibody-based therapeutics for neuroblastoma
  Prof A Sala
Applications accepted all year round

Funding Type

PhD Type

Metastatic neuroblastoma is a cancer of the nervous system that kills the majority of the affected children. Although there have been tremendous advances in the understanding of the molecular causes of the disease, patients are still treated with highly toxic mixtures of chemicals and radiation.
  Investigating Therapeutic Effect of Different Antioxidants in Friedreich’s Ataxia (FRDA)
  Dr S Anjomani-Virmouni
Applications accepted all year round

Funding Type

PhD Type

Friedreich’s ataxia (FRDA) is an inherited neurodegenerative disorder caused by epigenetic silencing of the frataxin gene. It is the most common inherited ataxia, affecting 1:50,000 Caucasians, and is characterised by neurodegeneration, cardiomyopathy, diabetes mellitus and skeletal deformities.
  PhD in Neuroimmunology - Unravelling the molecular basis of the association of genetic variation in the clusterin gene with risk of Alzheimer’s disease
  Prof B Paul Morgan, Dr R Sims
Application Deadline: 30 June 2020

Funding Type

PhD Type

Big genetic studies have changed thinking about AD, highlighted different possible causes and suggested new ways of treatment. The best of these studies are huge, multi-national.
  The phenotypic and functional identification of angiogenic T-cells for potential use to treat cardiovascular disease Project ID SAS0043
  Dr M Ross, Dr G Wright
Application Deadline: 31 May 2020

Funding Type

PhD Type

PROJECT DESCRIPTION. This project is based within the School of Applied Sciences at Edinburgh Napier University and is led by Dr.
  Exercise and nutritional status on metabolic factors, hormonal responses and inflammation in women
  Dr J Allgrove
Applications accepted all year round

Funding Type

PhD Type

Obesity is a major risk factor for chronic diseases such as type 2 diabetes, adverse cardiovascular events and metabolic syndrome-related disorders.
  Potential therapeutic effects of natural products in Human Papillomavirus (HPV) related cervical cancers
  Dr H Ashrafi
Applications accepted all year round

Funding Type

PhD Type

Cervical cancer is one of the most common types of cancer affecting women worldwide. Infection caused by high-risk human papillomaviruses (HPVs), especially type 16 and 18 are implicated in the etiology of most cervical cancers.
  Sex differences of ultra-endurance running: Profiling of female ultra-runners
  Dr H Moir
Applications accepted all year round

Funding Type

PhD Type

Ultra-endurance running has become increasingly popular, both in amateur and recreational athletes, with an exponential increase in the number of ultra-marathon finishers between 1998 and 2011 (Cejka et al., 2013; Hoffman & Krishnan 2013;).
  PhD Studentship: Influence of phytochemical administration on inflammation, redox balance and muscle regeneration following exercise in older and younger adults
  Dr T Clifford
Application Deadline: 26 June 2020

Funding Type

PhD Type

Reference number. SSEHS/TC. Start date of studentship. 1 October 2020. Closing date of advert. 26 June 2020. Interview date. July/August.
  Characterizing the aging human immune system (Ref: SF20/APP/TODRYK)
  Prof S Todryk
Applications accepted all year round

Funding Type

PhD Type

With a growing aging population, clinical and medical science is challenged with a range of age-related diseases, which it is compelled to try to address.
  Redeploying Rucaparib: Can PARP inhibitors alter deregulated cellular bioenergetics and overcome apoptosis resistance in cancer? (SF20/APP/WALDEN)
  Dr H Walden
Applications accepted all year round

Funding Type

PhD Type

Poly(ADP-ribose) polymerase inhibitors (PARPi) have received huge attention in oncology over recent years. They are FDA approved for use in BRCA1/2 defective breast and ovarian cancers with absent or dysfunctional homologous recombination repair function.
  Snake venomics and the quest for universally efficacious antivenoms (Ref: SF20/APP/MOSCHOS5)
  Dr S Moschos
Applications accepted all year round

Funding Type

PhD Type

Snakebite and envenomation is a WHO-declared neglected tropical disease plagues 5.5 million victims globally per year, causing nearly 150,000 deaths and 400,000 permanent disabilities.
  The Biological and Pathological Effects of Blinking (Ref: SF20/APP/MCDERMOTT1)
  Prof A McDermott
Applications accepted all year round

Funding Type

PhD Type

Blinking is essential to spread the tear film over the surface of the eye and so keeps the eye moist and lubricated to ensure a smooth surface for refraction of light and provision of essential nutrients and protective antimicrobial molecules.
  Understanding the Biological Properties of Medicinal Maggot Secretions (Ref: SF20/APP/MCDERMOTT2)
  Prof A McDermott
Applications accepted all year round

Funding Type

PhD Type

Medicinal maggots have long been used to promote healing of skin wounds. Their beneficial effects are, at least in part, due to secreted molecules that facilitate tissue rejuvenation, and that have anti-bacterial and anti-inflammatory actions.
  Understanding the effects of lung disease and vaping to the lung through breath-based bioanalytics (Ref: SF20/APP/MOSCHOS4)
  Dr S Moschos
Applications accepted all year round

Funding Type

PhD Type

Your breath contains a vast amount of information about you. whether you’ve had a drink, damaged your liver, your blood blood glucose levels, even type of breast cancer treatment can be assessed through breath.
  Exploring the role of histone deacetylase inhibitors as regulators of innate immune cells activation in periodontitis
  Dr F Flores-Borja
Applications accepted all year round

Funding Type

PhD Type

Second Supervisor. Rommel Chacon-Salinas (National Polytechnic Institute, Mexico). Background.
  Integrated analysis of the Intra-tumour Heterogeneity of Oral squamous cell carcinoma
  Dr I Sequeira
Applications accepted all year round

Funding Type

PhD Type

Cancer is a heterogeneous disease with unique genomic and phenotypic features that differ between individual patients and among different regions within the same tumour.
  Insights into eye disease: understanding the molecular basis of age-related macular degeneration
  Prof T Day, Dr S Clark
Applications accepted all year round

Funding Type

PhD Type

Dysregulation of innate immunity has been implicated as playing a key role in the development of age-related macular degeneration (AMD) – a major form of blindness in the industrialised world (see [1-5]).
  Dynamic cell fate decisions: linking mechanical signals and protein expression dynamics in the developing eye to understand human developmental disorders
  Dr Cerys Manning, Prof N Papalopulu
Applications accepted all year round

Funding Type

PhD Type

Inherited developmental disorders account for much of childhood visual impairment. Development of the eye requires cell fate decisions that balance stem cell proliferation and differentiation.
  Basal stem cells in the lung and their recognition of dying cells
  Prof T Hussell, Dr N Fujino
Applications accepted all year round

Funding Type

PhD Type

Stem cell division and differentiation is critical for barrier repair following inflammation, but the initial trigger for this process is unknown.
  Building the human endometrium in vitro: The role of macrophages in receptive and decidual endometrium to optimise reproductive health
  Dr E Mann, Dr Peter Ruane, Prof J Aplin, Dr L Mohiyiddeen
Applications accepted all year round

Funding Type

PhD Type

The human endometrium is a highly dynamic tissue that rapidly generates over ~20 days and differentiates to form a uterus lining receptive to embryo implantation, further transforming into decidua to support embryonic development, or breaking down before regenerating a few days later.
  Determining how immune responses are regulated at mucosal surfaces
  Prof M Travis, Prof D Thornton
Applications accepted all year round

Funding Type

PhD Type

The immune system must be primed to quickly respond to infection, but must also be tightly regulated so it ignores harmless substances and our own tissues.
  Do Altered host-microbial interactions promote oral inflammation during ageing?
  Dr J Konkel, Prof A McBain
Applications accepted all year round

Funding Type

PhD Type

As we age, the systems of our bodies become less able to function; rendering people increasingly infirm. Ageing affects our immune system, impeding our ability to both fight infection and maintain tolerance.
  Environmental control of dendritic cell activation and function during pulmonary type 2 inflammation
  Prof A MacDonald, Prof J Allen
Applications accepted all year round

Funding Type

PhD Type

Type 2 inflammation is a defining feature of infection with parasitic worms (helminths), as well as being responsible for widespread suffering in allergies.
  Exploiting tumour-promoting paracrine signals in solid cancers to turbocharge genetically redirected T cells
  Dr A Hurlstone, Prof R Edmondson
Applications accepted all year round

Funding Type

PhD Type

Adoptive cell therapy (ACT) using tumour infiltrating lymphocytes (TILs) or genetically redirected T cells are some of the most promising approaches to emerge recently for the treatment of metastatic disease.
  How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function
  Dr K Couper, Prof R K Grencis
Applications accepted all year round

Funding Type

PhD Type

Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state.
  Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni
  Dr J Cavet, Dr D Linton
Applications accepted all year round

Funding Type

PhD Type

Campylobacter jejuni is a globally important food-borne pathogen causing an estimated 400-500 million cases of acute human gastroenteritis each year.
  Tackling antibiotic resistance: developing a vaccine against gonorrhoea
  Prof J P Derrick, Dr F Hayes
Applications accepted all year round

Funding Type

PhD Type

Gonorrhoea is caused by the Gram-negative bacterium Neisseria gonorrhoeae and is a serious public health problem in developing and developed countries.
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