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Medicine PhD Projects, Programmes & Scholarships in the UK
We have 965 Medicine PhD Projects, Programmes & Scholarships in the UK
We have 965 Medicine PhD Projects, Programmes & Scholarships in the UK
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Common Peripheral Inflammatory Diseases: An Underestimated Stroke Risk Factor
A potential trigger for cryptogenic strokes in young adults is the long-lived hyper-inflammation associated with chronic peripheral inflammatory diseases including inflammatory bowel disease (IBD) and rheumatoid arthritis (RA). Read more
Polmorphisms in cytosolic drug metabolising enzymes: a combined proteomics and modelling approach to clinical impact
Cytosolic drug metabolising enzymes such as aldehyde oxidase play a pivotal role in metabolism of drugs. However, research into cytosolic enzymes has been relatively neglected in comparison with membrane bound enzymes such as cytochrome P450 (CYP) and uridine 5’-glucuronosyltransferases (UGTs). Read more
Selective drug uptake by cell surface transporters
Cell surface transporters and not diffusion is responsible for the transfer of metabolites across a cell’s membrane. Many types of drugs are structurally very similar to natural metabolites and as a consequence they are treated by the cell as though they are the natural homologue. Read more
Modulation of the Hippo signalling pathway to enhance cardiac regenerative capacity
Common heart diseases such as heart failure (HF) and coronary heart disease (CHD) are characterized by cardiomyocyte loss due to necrosis and apoptosis. Read more
Mechanistic models for protein binding and transport in organ impairment
When evaluating impact of disease on drug response, measurement of total drug concentration is typically used as surrogate for free drug concentration and pharmacological effect. Read more
Mechanisms of metabolic remodelling in obesogenic/diabetic cardiomyopathy
Obesity is a worldwide public health concern and is one of the co-morbidities associated with the development of type 2 diabetes. Read more
Investigating the role of bioactive lipids in skin health
Human skin depends on systemic provision of fatty acids that are important to maintain the integrity of the epidermal barrier as well as to support the associated immune and inflammatory reactions. Read more
Inflammation and brain tumour growth
Our basic research aims to understand fundamental mechanisms of inflammation, such as the activation of the NLRP3 inflammasome. Read more
Understanding and optimising motor cortex plasticity
Motor learning is a key skill required at all stages of life but is crucially important for recovery and development. A mechanistic understanding of the biological processes that underpin skill acquisition in healthy and pathological states is an important scientific and clinical goal. Read more
Cardiovascular effects of combination therapy with VEGF inhibitors and immune checkpoint inhibitors in cancer treatment
The success in cancer therapy observed in the past two decades is tightly associated with the introduction of new therapeutic strategies, which include combination therapies. Read more
Investigate the novel therapeutic potential for treating heart failure in diabetes
Heart failure is the most common cause of mortality in diabetes patients, but current diabetes therapies have a limited impact on the incidence of heart failure in diabetic populations. Read more
Circadian clock control of adipocyte metabolism
Obesity is a major public health issue affecting one third of UK adults, and an estimated 2.1 billion individuals worldwide. The role of circadian clock dysfunction in the development of obesity is becoming clear, with disruptive lifestyles (e.g. Read more
Statistical genetics approaches to investigate autoimmune inflammatory muscle disease for precision medicine
Keywords. statistical genetics, precision medicine, autoimmune, idiopathic inflammatory myopathies, myositis, disease classification, machine learning. Read more
Assessment of nutritional status, body composition, motor- and neurodevelopment in preterm and term children aged 2-4 years: an international, multicentre study.
Oxford Brookes University,. Faculty of Health and Life Sciences,. Department of Sport, Health Sciences and Social Work. Masters by Research one year, full-time self-funded programme. Read more
Neurophysiological and pharmacological assessment of endogenous pain modulation in the human spinal cord
Location. St Luke’s Campus. Department of Clinical and Biomedical Sciences, RILD Building, RD&E Hospital Wonford, Exeter. Read more