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Molecular Biology PhD Projects, Programs & Scholarships in the UK

We have 670 Molecular Biology PhD Projects, Programs & Scholarships in the UK

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Showing 121 to 150 of 670
  Probing the structure and function of neural connectomes
  Dr W Schafer
Application Deadline: 3 December 2019

Funding Type

PhD Type

Connectomics offers the possibility of understanding the brain in terms of its neural components and their interactions. However, such a reductionist understanding of the brain presents many challenges.
  Reconstitution of a ciliary rootlet for cryoEM structure determination.
  Dr A Carter
Application Deadline: 3 December 2019

Funding Type

PhD Type

Cilia are found on all cells and have functions ranging from receiving signals to moving mucus out of the lungs. At their feet are basal bodies and below these are long striated filaments known as rootlets.
  Role of glutamate receptor dynamics in synaptic plasticity
  Dr I Greger
Application Deadline: 3 December 2019

Funding Type

PhD Type

Information transfer in the brain occurs at synapses, where memories are stored as a result of synaptic plasticity processes. AMPA-type glutamate-receptors (AMPARs), the main mediators of signal transmission, centrally contribute to synaptic plasticity.
  Structural and biochemical analysis of chromosome segregation in yeast
  Dr D Barford
Application Deadline: 3 December 2019

Funding Type

PhD Type

Our research is focused on understanding the mechanisms and regulation of chromosome segregation in mitosis. During the cell cycle, accurate chromosome segregation ensures that both daughter cells inherit the correct complement of chromosomes.
  Structural and biochemical studies of macromolecular complexes involved in telomere maintenance
  Dr K Nguyen
Application Deadline: 3 December 2019

Funding Type

PhD Type

Linear eukaryotic chromosomes are capped with telomeres, which protect chromosomes against degradation and inter-chromosomal fusion and thus are essential for maintaining genome integrity.
  Structure and mechanisms of the eukaryotic replisome
  Dr J Yeeles
Application Deadline: 3 December 2019

Funding Type

PhD Type

Each time a cell divides it must duplicate its genetic material. The extraordinary molecular machine responsible for this task is called the replisome.
  Sub-nanometer resolution imaging of individual biological molecules by electron cryomicroscopy
  Dr C Russo
Application Deadline: 3 December 2019

Funding Type

PhD Type

Many fundamental problems in biology relate to how proteins interact with DNA and RNA. The difficulty in addressing these questions arises from the limitations of current microscopes and the complex and fragile nature of biomolecules.
  Supra-molecular architecture of neurotransmitter receptor complexes
  Dr R Aricescu
Application Deadline: 3 December 2019

Funding Type

PhD Type

Chemical synapses are cellular connectors that define the organization and function of neuronal circuits and, as a result, the fundamental ability of the brain to acquire and store information.
  Symmetry breaking in early mammalian organogenesis: the mechanical and cellular basis of gut tube formation
  Dr K McDole
Application Deadline: 3 December 2019

Funding Type

PhD Type

The McDole lab is a newly established lab that studies how the mouse embryo builds complex structures such as a beating heart or the intricate folds of the brain from initially simple and uniform starting materials.
  Systematic cell reprogramming –transdifferentiation– cell fate and evolution using computational approaches.
  Dr J Gough
Application Deadline: 3 December 2019

Funding Type

PhD Type

The field of regenerative medicine was stunned in 2007 by the possibility of creating stem cells from adult human cells (1). Since then it has been shown that it is also possible to trans-differentiate from one mature human cell type to another.
  The role of crosslink repair in primordial germ cells and germ cell tumours
  Dr G Crossan
Application Deadline: 3 December 2019

Funding Type

PhD Type

Germ cells are uniquely tasked with passing on genetic information. They ultimately give rise to sperm or eggs that come together to produce a new organism with new germ cells.
  The structural basis of viral transport by dynein/dynactin.
  Dr A Carter
Application Deadline: 3 December 2019

Funding Type

PhD Type

Viruses are too large to move inside cells unless they hijack cytoskeletal motors such as the microtubule motor dynein. Remarkably dynein is co-opted by all classes of virus.
  Towards RNA-mediated peptide synthesis
  Dr J Sutherland
Application Deadline: 3 December 2019

Funding Type

PhD Type

This project aims to build on recently discovered activation chemistry and shed some light on the origin of ribosomal peptide synthesis.
  Wiring and transmission specificity of serotonin system in the brain
  Dr J Ren
Application Deadline: 3 December 2019

Funding Type

PhD Type

The serotonin (5HT) system is the most frequently targeted neural system pharmacologically for treating psychiatric disorders, including depression and anxiety.
  Elucidating the interplay between mitochondrial dynamics, organelle contact sites and metabolic (re)programming (On the University’s application portal, please select "PhD in Medical Science at the MRC Mitochondrial Biology Unit").
  Dr J Prudent
Application Deadline: 30 June 2020

Funding Type

PhD Type

Mitochondria house hundreds of biochemical reactions involved in processes critical for the survival and homeostatic adaptation of the cell.
  Regulation of mitochondrial gene expression (On the University’s application portal, please select "PhD in Medical Science at the MRC Mitochondrial Biology Unit").
  Dr M Minczuk
Application Deadline: 30 June 2020

Funding Type

PhD Type

MRC Mitochondrial Biology Unit. The key objective of this PhD project is to study nuclear-encoded proteins involved in mitochondrial (mt-) RNA metabolism, in order to understand how their dysfunction is linked to human mitochondrial pathologies.
  Role and mechanism of mitochondrial transport proteins (On the University’s application portal, please select "PhD in Medical Science at the MRC Mitochondrial Biology Unit").
  Prof E Kunji
Application Deadline: 30 June 2020

Funding Type

PhD Type

Mitochondria are central to the utilization of sugars and fat by the eukaryotic cell in order to synthesise ATP via oxidative phosphorylation.
  EPSRC Centre for Doctoral Training in Molecular Sciences for Medicine - 4 year PhD Studentships

Funding Type

PhD Type

Applications are invited from suitably qualified graduates for fully funded 4-year PhD studentships in the area of Molecular Sciences for Medicine (MosMed) and will focus on unmet medical needs.
  Rotation PhD Programme in Plant and Microbial Sciences

Funding Type

PhD Type

Rotation PhD Programme in Plant and Microbial Sciences. Four-year multi-disciplinary PhD opportunity in genetics, genomics, cell biology, microbiology, molecular biology, crop science, biological chemistry, applied mathematics, computational and systems biology.
  Do urine vesicles offer a fingerprint of Chronic Kidney Disease
  Dr E Verderio-Edwards
Application Deadline: 4 November 2019

Funding Type

PhD Type

There are almost four million people in the UK affected by chronic kidney disease (CKD), a silent and progressive kidney damage for which there is no cure.
  Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks
  Dr A Antonysunil
Applications accepted all year round

Funding Type

PhD Type

The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children.
  Exploring treatment resistance in mantle cell lymphoma
  Dr C Hutchinson, Prof S Rule
Application Deadline: 27 October 2019

Funding Type

PhD Type

The University of Plymouth’s Faculty of Health. Medicine, Dentistry & Human Sciences is seeking a highly motivated PhD candidate with outstanding abilities and enthusiasm for research.
  Adapt or die? Understanding how bacterial bioflms evolve under stress (WEBBERQ20DTP)
  Dr M Webber
Application Deadline: 25 November 2019

Funding Type

PhD Type

Most bacteria in nature exist within a biofilm; a community of aggregated cells. Biofilms are important in many industrial contexts and most bacterial infections include biofilms.
  Antibiotics; good gone bad? Impact on liver immunity and susceptibility to injury (BERAZAQ20DTP2)
  Dr N Beraza
Application Deadline: 25 November 2019

Funding Type

PhD Type

The use of antibiotics has saved millions of lives. Worryingly, antibiotics modify dramatically the composition of our intestinal microbiome and can lead to the permanent loss of certain species.
  Gut microbial metabolism at the mucosal surface (JUGEQ20DTP1)
  Prof N Juge
Application Deadline: 25 November 2019

Funding Type

PhD Type

The human body harbours a diverse and dense population of commensal bacteria, which exerts key functions in terms of nutrition and health.
  Metabolism as a regulator of stressed haematopoiesis; implications for liver function during ageing. (BERAZAQ20DTP1)
  Dr N Beraza
Application Deadline: 25 November 2019

Funding Type

PhD Type

During homeostasis, our body’s immunological defence relies on the expansion and differentiation of haematopoietic stem cells (HSC).
  Microbial ecology and metagenomics of a foodborne pathogen (MATHERQ20DTP)
  Dr A Mather
Application Deadline: 25 November 2019

Funding Type

PhD Type

Campylobacter is the commonest bacterial cause of diarrhoeal disease in the UK, where is it most often associated with poultry, and amongst the top five causes of diarrhoeal disease in low and middle-income countries.
  Microbiota and vascular health (ROBINSONQ20DTP)
  Dr S Robinson
Application Deadline: 25 November 2019

Funding Type

PhD Type

Angiogenesis is the formation of blood vessels from pre-existing vessels. Angiogenesis is essential for maintaining healthy physiological processes and for the revascularisation of tissues following an injury.
  Novel autophagy pathways for the control of influenza virus infection (WILEMANQ20DTP)
  Prof T Wileman
Application Deadline: 25 November 2019

Funding Type

PhD Type

The recent outbreaks of avian influenza and the threat of a human influenza pandemic has highlighted the need to understand prevention and control of this virus by developing effective antiviral therapies.
  Type 1 Resistant Starch: A journey through the gut (EDWARDSQ20CASE)
  Dr C Edwards
Application Deadline: 25 November 2019

Funding Type

PhD Type

Most adults in the UK are overweight or obese, and the food industry are urgently seeking to develop healthier processed foods. One solution is to replace ‘available starch’ in the diet with ‘resistant starch’ that is not digested to glucose in the upper-gut.
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