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We have 98 Pathology PhD Projects, Programmes & Scholarships in the UK

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Pathology PhD Projects, Programmes & Scholarships in the UK

We have 98 Pathology PhD Projects, Programmes & Scholarships in the UK

Control of bone shape and function by the extracellular matrix Fibrillin-1

Bones are tightly regulated structures that remodel their structure to adapt to changes in their mechanical environment. With ageing, this mechanical response is often dampened, leading to bone loss and weakness. Read more

Unravelling the Intricacies of Stress Hormone Regulation

Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more

Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

Normative modelling of resting-state EEG across the lifespan for application in the early diagnosis of neurodegenerative disorders including Alzheimer’s disease

With a rapidly aging human population worldwide, neurodegenerative diseases represent a pressing medical and societal concern. Given the increase in life expectancy, dementia is expected to affect almost 152 million people by 2050 (Alzheimer’s Disease International, 2018). Read more

Investigating the neuro-stromal-immune interactions in inflammageing and osteoarthritis.

Ageing is associated with a higher risk of developing multiple chronic conditions (multimorbidity) including osteoarthritis. Age-associated chronic low-grade inflammation (inflammageing) is a hallmark of osteoarthritis. Read more

Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

  Research Group: Chemistry and Biosciences
The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

  Research Group: Chemistry and Biosciences
Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more

Investigation of the extracellular matrix as a regulator of Parkinson’s progression

  Research Group: Chemistry and Biosciences
Parkinson’s is the 2nd most common neurodegenerative disease, affecting around 1 in 20 people aged over 65. In the UK, the number of affected people is set to rise by 50% over the next 50 years due to ageing populations. Read more

An investigation on the association of high risk human papillomavirus (HPV) types with colonic adenomata and adenocarcinomas: a UK population based study

This PhD studentship invites application for a study “investigating the association between high risk human papillomavirus (HPV) types and colonic adenomata and adenocarcinomas in a UK population”.  Colorectal cancer (CRC) is an important public health problem worldwide occupying most frequent causes of cancer-related mortality. Read more

MSc by Research: Molecular characterisation of the factors driving lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive disease that results in an irreversible decline in lung function.  At present IPF is normally fatal and the median survival is between 2 and 5 years after diagnosis. Read more

Role of the endosomal pathway in regulating sleep and circadian rhythms

Ageing and many neurodegenerative disorders are characterised by a progressive loss of neurons in particular brain regions leading to behavioural changes including cognitive decline, sleep disruption and circadian dysregulation. Read more

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