Birkbeck, University of London Featured PhD Programmes
The Francis Crick Institute Featured PhD Programmes
Norwich Research Park Featured PhD Programmes
The University of Manchester Featured PhD Programmes
European Molecular Biology Laboratory (Heidelberg) Featured PhD Programmes

Pathology PhD Projects, Programs & Scholarships in the UK

We have 99 Pathology PhD Projects, Programs & Scholarships in the UK

  • Pathology×
  • United Kingdom×
  • clear all
Order by 
Showing 31 to 60 of 99
  Investigating the role of bioactive lipids in skin health
  Prof A Nicolaou, Prof C A O'Neill
Applications accepted all year round

Funding Type

PhD Type

Human skin depends on systemic provision of fatty acids that are important to maintain the integrity of the epidermal barrier as well as to support the associated immune and inflammatory reactions.
  How do phosphodiesterases contribute to the pathophysiology of heart failure?
  Prof A Trafford, Dr K Dibb
Applications accepted all year round

Funding Type

PhD Type

Heart failure (HF) remains a major cause of death with worse 5-year survival than all forms of cancer combined. This project seeks to understand the mechanisms that underlie two important contributing factors to death in HF patients; i) contractile failure and, ii) the increased propensity for arrhythmias.
  GW4 BioMed MRC DTP PhD studentship: Using nanotechnology, structural biology and genome editing to study how fungal receptors promote the spread of lethal diseases
  Dr N Brown
Application Deadline: 25 November 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the ‘GW4 BioMed MRC Doctoral Training Partnership’ which is offering up to 18 studentships for entry in September 2020.
  Creating “super” regulatory T cells to combat rejection, GVHD and autoimmunity through retroviral gene manipulation
  Dr N Jones, Dr S Lee
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Foxp3+CD25+CD4+ regulatory T cells (Treg) have been shown to be essential for the induction of tolerance to foreign organ transplants in experimental models.
  Targeting the Role of Myeloid Steroid Metabolism in Chronic Inflammation
  Dr R Hardy, Dr P Foster
Applications accepted all year round

Funding Type

PhD Type

Background. Myeloid derived cell populations such as macrophages play a critical role in the early innate immune response, whilst dendritic cells are essential in bridging the progression to an adaptive immune response.
  Using live-cell imaging of the immune response to investigate host-pathogen interactions during infection.
  Prof R May
Application Deadline: 10 January 2020

Funding Type

PhD Type

My group is interested in the molecular and cellular mechanisms that occur during host-pathogen interactions.
  Electrophysiological changes in ion channels in human haploid and diploid (spermatozoa and lymphocytes) after nanoparticle exposure
  Research Group: Chemistry and Biosciences
  Dr L Shang, Dr M H Brinkworth, Prof D Anderson
Applications accepted all year round

Funding Type

PhD Type

Nanomaterial-mediated delivery represents a promising technique for repro- and geno- toxicology with a potential to improve the safety and efficacy of existing methodologies, including experimental gene therapy and sperm-mediated gene transfer.
  Live-imaging and genetic approaches to explore cross-talk between tissue damage, immune dysfunction and infection within novel animal models of cystic fibrosis
  Dr H Weavers, Prof E Mahenthiralingam, Dr D N Sheppard
Application Deadline: 25 November 2019

Funding Type

PhD Type

Cystic fibrosis (CF) is a genetic disorder driven by mutations in the CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) gene.
  Neutrophils and Chemokine Signalling in the Tumour Immune Micro-environment and Progression
  Dr T Iwata
Applications accepted all year round

Funding Type

PhD Type

Checkpoint inhibitor immunotherapy is promising, however still requires an improvement in response and development of markers to predict the patients who would benefit from this therapy.
  An integrated approach to the study of cellular interactions with amyloid
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford
Applications accepted all year round

Funding Type

PhD Type

The formation of insoluble amyloid fibrils is associated with a spectrum of human disorders, the amyloidoses, which include Alzheimer’s, Parkinson’s, type 2 diabetes and dialysis related amyloidosis (DRA).
  Gastroesophageal reflux in respiratory disease: pathogenic role and improved management
  Prof L Houghton
Applications accepted all year round

Funding Type

PhD Type

Gastroesophageal reflux (GER) is associated with many lung diseases, including but not limited to idiopathic pulmonary fibrosis (IPF), non-IPF interstitial lung disease (ILD), chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), non-CF bronchiectasis, asthma and idiopathic chronic cough.
  Genome and transcriptome sequencing and functional analysis to find new mutation types in patients with inherited blindness
  Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Human inherited retinal dystrophies (IRDs) result from mutations in over 200 different genes, many of them first implicated by the Leeds Vision Research Group (eg Panagiotou E et al 2017, AJHG 100:960-968; El-Asrag M et al 2015, 96:948-54).
  How human teeth form and how that process fails in the inherited condition amelogenesis imperfecta
  Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Amelogenesis is the process of enamel formation and is essential for the development of functional teeth. Amelogenesis imperfecta (AI) is a failure of that process.
  Identification and functional characterisation of BRIT1/MCPH1 synthetic lethal genes to treat breast and ovarian cancer
  Dr S Bell, Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Women who have undergone surgery for breast and ovarian cancer often have additional chemotherapy to kill residual cancer cells and prevent recurrence.
  Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
  Dr S Papa
Applications accepted all year round

Funding Type

PhD Type

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow.
  The functional characterization of the tumour suppressor gene CSMD1 in breast cancer
  Dr S Bell
Applications accepted all year round

Funding Type

PhD Type

CUB and Sushi multiple domains protein 1 (CSMD1) maps to 8p23, a region deleted in many cancers including breast cancer. Our previous work has established that CSMD1 is an independent prognostic marker in ductal breast cancer, with reduced expression associated with high tumour grade and poor survival1.
  Understanding drug-resistance in myeloid cancer
  Dr P Laslo
Applications accepted all year round

Funding Type

PhD Type

Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory.
  International PhD Academy: Medical Research

Funding Type

PhD Type

Our vision is to impact locally, nationally and globally on biomedical and clinical research with a primary emphasis on health outcomes.
  Development of treatment for Osteoarthritis by blocking metalloproteinases
  Prof G Bou-Gharios
Applications accepted all year round

Funding Type

PhD Type

MMP13 (collagenase 3) plays a vital role in the pathogenesis of osteoarthritis (OA) because MMP13 preferentially cleaves type II collagen, the main component of cartilage, and both MMP13 levels and enzymatic activity are enhanced in OA.
  Understanding basic biological mechanisms and the development of targeted therapies
  Prof G Bou-Gharios
Applications accepted all year round

Funding Type

PhD Type

The PhD proposal is aimed at understanding some of the fundamental mechanism(s) that control extracellular matrix (ECM) proteins and to develop new technologies and therapeutic based on changes in fibroblast gene expression profiling and surface antibodies during the development of connective tissue fibrosis.
  Understanding bone mass using collageneases and aggrecanases
  Prof G Bou-Gharios
Applications accepted all year round

Funding Type

PhD Type

Bone is not only essential for locomotion, support and protection but crucial for many aspects of animal and human health. Specifically, bone is a calcium/phosphorous reservoir, is integral to glucose metabolism, houses the hematopoietic system and cross-talks with renal and reproductive systems.
  Examining Histoplasmosis in household and community environments at the human-animal interface
  Dr C Scantlebury, Prof A J McCarthy, Dr G Pinchbeck, Dr D Wooton
Applications accepted all year round

Funding Type

PhD Type

Little is known about the current prevalence or transmission of Histoplasmosis despite its persistence in Sub-Saharan Africa, representing a public health blind spot (Oladele et al., 2018).
  Exploring the role of meiotic proteins in cancer
  Dr U McClurg
Applications accepted all year round

Funding Type

PhD Type

Cancer is one of the main causes of death worldwide. The main challenge is the development of treatments specifically targeting cancers without killing healthy cells.
  The Consequences of Transmission Heterogeneities for Disease Outbreaks
  Prof A Fenton, Prof M Viney
Application Deadline: 8 January 2020

Funding Type

PhD Type

There are ever-increasing concerns about the threat of emerging infectious diseases, in both wildlife (e.g., rabies, chytridiomycosis in amphibians, white nose syndrome in bats etc.) and humans (e.g., Ebola, pandemic influenza, chikungunya fever etc.).
  EPSRC Centre for Doctoral Training in Sustainable Approaches to Biomedical Science: Responsible and Reproducible Research - SABS

Funding Type

PhD Type

Good degree in the Physical or Life Sciences? Interested in biological or medical research? We offer fully-funded PhD places across the Oxford Doctoral Training Centre programmes.
  Can genetics-led immunologic investigation identify novel common regulators shared across immune-mediated inflammatory diseases? #NDORMS-2020/2
  Dr L Chen, Prof P Bowness
Application Deadline: 10 January 2020

Funding Type

PhD Type

Liye Chen. https://www.ndorms.ox.ac.uk/team/liye-chen. Paul Bowness. https://www.ndorms.ox.ac.uk/team/paul-bowness. Immune-mediated inflammatory diseases (IMIDs) are a group of incurable diseases that share inflammatory pathways and cause substantial personal and socioeconomic burdens.
  Utilising mechanistic mathematical models to understand cellular heterogeneity of healthy human tendons #NDORMS-2020/7
  Dr S Snelling, Dr A Cribbs, Prof S Waters
Application Deadline: 10 January 2020

Funding Type

PhD Type

Tendons efficiently transfer force from muscles to the skeleton and are fundamental to all forms of motion. Tendons possess a distinct hierarchical organisation.
  A molecular analysis of centrioles, centrosomes and cilia
  Prof J Raff
Application Deadline: 10 January 2020

Funding Type

PhD Type

Centrioles are barrel-shaped structures that organise the assembly of two crucial cell organelles. centrosomes and cilia.
  Anti-inflammatory actions of metabolites on macrophages and microglia
  Prof D R Greaves
Application Deadline: 10 January 2020

Funding Type

PhD Type

Background. It is clear that inflammation underlies many important chronic disease states in both the central nervous system (CNS) e.g.
  Control of T cell activation by accessory receptors
  Dr O Dushek
Application Deadline: 10 January 2020

Funding Type

PhD Type

T cells orchestrate immune responses crucial for the elimination of infections and cancers. They do this by initiating a diverse set of effector responses when their T cell surface receptors (TCRs) recognize these threats.
Show 10 15 30 per page


FindAPhD. Copyright 2005-2019
All rights reserved.