This project is funded jointly by the Dunhill Medical Trust and the Advanced Care Research Centre Academy. The. Advanced Care Research Centre (ACRC). Read more
'APPLY THROUGH INSTITUTION WEBSITE LINK'. Prostate cancer (PC) is a leading cause of cancer mortality in men in the western world, with over 10,000 dying every year of the disease in the UK alone. Read more
Reward sensitivity (the value attributed to rewarding outcomes by an individual) is attenuated in people with mood disorders and is known to be mediated by dopaminergic signalling. Read more
The primary pathology of dementia with Lewy bodies (DLB) is alpha-synuclein, however multiple studies have demonstrated that Alzheimer’s disease (AD) related pathologies (tau and beta amyloid) play an important role in disease progression driving spread of pathology and accelerating cognitive decline. Read more
Overview. Immune checkpoint pathways determine the abilities of human malignant tumours to escape cytotoxic immune attack and thus progress the disease. Read more
Overview. Immune checkpoint pathways determine the abilities of human malignant tumours to escape cytotoxic immune attack and thus progress the disease. Read more
Essential tremor (ET) is the most common reason for referral to a neurologist, with a prevalence of around 1-3%. Sufferers experience involuntary shaking of the limbs at around 5Hz; mild cases cause only social embarrassment, but more severe tremor can be disabling and limit activities of daily living. Read more
The Systems Immunity Research Institute at Cardiff University is delighted to offer a full-time PhD studentship in Bioinformatics / Computational Biology funded by the Cardiff Cancer Research Hub for 3 years, starting on 1 April, 1 July or 1 October 2023 depending on the candidate's preference and availability. Read more
Supervision Team: . Dr Rhodri Davies. / . Dr Michele Orini. / . Dr Carole Sudre. . A MRes+PhD funded studentship is available in a partnership between the MRC Unit for . Read more
Cell surface transporters and not diffusion is responsible for the transfer of metabolites across a cell’s membrane. Many types of drugs are structurally very similar to natural metabolites and as a consequence they are treated by the cell as though they are the natural homologue. Read more
Human skin depends on systemic provision of fatty acids that are important to maintain the integrity of the epidermal barrier as well as to support the associated immune and inflammatory reactions. Read more
Heart failure is the most common cause of mortality in diabetes patients, but current diabetes therapies have a limited impact on the incidence of heart failure in diabetic populations. Read more
Radiotherapy (RT) is a common standard therapy used for locally advanced head and neck malignant tumours. The radiation triggers the production of free radicals that can cause direct damage to the DNA structure of malignant cells. Read more
Knee osteoarthritis is a complex and incapacitating disease influenced by a variety of factors including the loading environment, muscle strength and endurance. Read more
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