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Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK
We have 110 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK
We have 110 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK
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Cell-type dependent pharmacological regulation of cellular mitophagy for therapeutic application in Parkinson’s disease
The cellular quality-control process of mitophagy, entailing selective degradation of defective mitochondria (following damage to their DNA) by the process of autophagy, has attracted considerable research interest. Read more
Water fingerprinting for health and lifestyle assessment
The. Centre for Sustainable & Circular Technologies. at the University of Bath is inviting applications for the following funded PhD project commencing in October 2022. Read more
Modular Synthetic Platform for the Optimisation of Fragment Hits Using Bifunctional 3-D Building Blocks
Modular Synthetic Platform for the Optimisation of Fragment Hits Using Bifunctional 3-D Building Blocks. Supervisor. Peter O’Brien. Read more
Fragment-Based Lead Generation of Small Molecule Inhibitors of the Nsp3 Macrodomain in SARS-CoV-2 – Towards New Antivirals for the Treatment of COVID-19
Fragment-Based Lead Generation of Small Molecule Inhibitors of the Nsp3 Macrodomain in SARS-CoV-2 – Towards New Antivirals for the Treatment of COVID-19. Read more
Catalytic Asymmetric ‘Clip-Cycle’ Reactions: Synthesis of Heterocycles Important in Drug Discovery
Cyclic ethers and amines are ubiquitous in biologically active natural and non-natural products. However, despite this prevalence and importance, there is no strategy for their asymmetric synthesis which is independent of heteroatom and/or ring size. Read more
Designing inhibitors of protein-protein interactions for bacterial cell division for specific antibiotics (BEEKMANA_U23SF)
Antibiotic-resistant pathogens are a huge threat in healthcare. The last resorts of conventional antibiotic drugs are unable to treat multi-resistant strains in patients. Read more
PhD Studentship Opportunity: Blade spray mass spectrometry for characterisation and quantification of mutagenic impurities in pharmaceutical reaction mixtures
Blade spray mass spectrometry is a new and exciting development to characterise molecules rapidly, and accurately, at very low (sub parts per billion) levels in complex matrices. Read more
Polmorphisms in cytosolic drug metabolising enzymes: a combined proteomics and modelling approach to clinical impact
Cytosolic drug metabolising enzymes such as aldehyde oxidase play a pivotal role in metabolism of drugs. However, research into cytosolic enzymes has been relatively neglected in comparison with membrane bound enzymes such as cytochrome P450 (CYP) and uridine 5’-glucuronosyltransferases (UGTs). Read more
PhD in catalysis and natural product synthesis
The Arseniyadis group (. https://arseniyadislab.sbcs.qmul.ac.uk/). is principally interested in the discovery and development of new synthetic methods which allow atom, step and redox-economy while providing high structural and functional complexity as well as stereocontrol. Read more
PhD in synthetic methodology and natural product synthesis
The Arseniyadis group (. https://arseniyadislab.sbcs.qmul.ac.uk/). is principally interested in the discovery and development of new synthetic methods which allow atom, step and redox-economy while providing high structural and functional complexity as well as stereocontrol. Read more
Investigation of Formulation Design Solutions for Low Global Warming Potential Pulmonary Drug Delivery Systems
Research Group:
Chemistry and Biosciences
In 1987 the Montreal Protocol defined a pathway to eliminate the compounds proven to be harmful for the ozone, such as chlorofluorocarbon (CFC) employed as propellants in pressurised metered dose inhalers (pMDIs). Read more
Medicinal Chemistry Project: Synthesis of novel small molecules for the potential treatment of the asbestos induced lung cancer mesothelioma
The Project. In developing a new therapeutic agent, there are two questions to address. how to get the potential drug to the specific site in the body where it is needed and second, does it do what we want it to do at the target site and without undesirable side effects. Read more
Novel Electrochemical and Photochemical C-H Activation Methods for Heterocycle Synthesis and applications in total synthesis
The Project. Saturated oxygen and nitrogen containing heterocycles are widespread across natural products and pharmaceutically active ingredients. Read more
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Linking epigenomics with cellular senescence to identify novel therapeutics for osteoarthritis
Osteoarthritis (OA) is caused by degradation of cartilage and accompanying structural changes to surrounding tissues in the articulating joints. Read more
Targeted nanoparticles for high-dose intracellular delivery of antibiotics
Supervisory Team: Nick Evans, Sumeet Mahajan, Seung Lee, Tracey Newman. Project description. Many bacteria are becoming resistant to antibiotics, and so new treatments and strategies are required. Read more