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We have 97 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

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Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

We have 97 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

Formulation of heterogenous solid dispersions produced by spray drying and hot-melt extrusion for improved delivery of amorphous drugs

  Research Group: Pharmacology and Experimental Therapeutics
Production of the amorphous solid dispersions (ASDs) is a one of the methods of improving of physicochemical properties of an active pharmaceutical ingredient (API) such as its solubility and physicochemical stability. Read more

Structural biology tools to investigate and target ubiquitin system proteases in cancer

Ubiquitination targets proteins for degradation and regulates virtually all cellular signalling pathways in eukaryotes. The human genome encodes over 50 ubiquitin specific proteases (USPs) that cleave ubiquitin from modified proteins to salvage them from proteasomal degradation. Read more

Development and Application of Enabling Methods for Drug Discovery

Transient protein-protein interactions (PPIs) control all cellular processes relevant to health and disease. Thus, a major problem in life-sciences research is to understand and manipulate PPIs with molecular and temporal resolution. Read more

Mechanistic design of effective pharmaceutical cocrystal formulations

It is estimated that more than 70 percent of the compounds in the pharmaceutical pipeline can be poorly water-soluble. Since solid drug forms must dissolve before absorption can occur, strategies to improve drug solubility and dissolution are a continuous need. Read more

Shared decision making and psychosis – whose voice counts in the conversations about stopping or reducing antipsychotic medication

Prescribing antipsychotics has increased steadily in England over the last decade. For serious mental health conditions like schizophrenia, they are prescribed with the view of keeping the patient on them indefinitely. Read more

Crystal engineering new, more effective medicines.

RESEARCH PROJECT. To uncover pharmaceutical problems, our team collaborates with a wide range of disciplines, including pharmacists, pharmaceutical scientists, chemists and engineers at internationally renowned pharmacy departments and at multinational pharmaceutical companies. Read more

The development of new antiviral agents targeting HIV-1

Even before the current global COVID-19 pandemic, the threat posed to human health by viruses was extensive and although significant progress in targeting some viruses (e.g., HIV-1 and hepatitis C) has been made, challenges remain. Read more

Drug metabolism - prediction, detection, and isolation

Electrosynthesis (ES) is a green methodology for preparing and interpreting drug metabolites linked to toxicology. ES describes the synthesis of chemical compounds in an electrochemical cell. Read more

How to regulate plasticity in the brain

The Kwok Lab at the School of Biomedical Science invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Chemically Modified Therapeutic Nucleic Acids for Neurological Diseases

Therapeutic oligonucleotides are unique in targeting mRNA particularly those that cannot be addressed by conventional small molecule drugs or therapeutic antibodies, their potential is growing fast. Read more

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