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Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

We have 103 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

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Chemistry

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United Kingdom

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We have 103 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

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Identification and development of compounds targeting childhood brain cancer

Supervisory Team.   Profs Ali Tavassoli. Project description. We are seekign an outstanding chemistry student with an interest in chemical biology to work on a project to identify and develop inhibitors of a currently untreatable form of childhood brain cancer called Diffuse Intrinsic Pontine Glioma (DIPG). Read more

Stabilizers of the interaction between 14-3-3 and hDM2/hDMX

  Research Group: School of Chemistry
Transient protein-protein interactions (PPIs) control all cellular processes relevant to health and disease. Selective modulation of individual PPIs would thus facilitate both a greater understanding of biological mechanisms and provide new opportunities for therapeutic intervention. Read more

Development of Novel Bioconjugation Approaches

Recent efforts in our group have sought to selectively exploit the reactivity of a transient intermediate generated from a stable precursor for applications in synthesis, medicinal chemistry, and chemical biology. Read more

Discovery of novel cancer immunotherapeutic agents

Although cancer therapeutics, mainly chemotherapy and radiotherapy, have been extremely useful in the treatment of cancer, this disease is still associated with high mortality. Read more

Towards particle design of pharmaceutical crystals

This project is being pursued in collaboration with AstraZeneca and the successful applicant will be part of a larger research group supervised by Dr Cruz-Cabeza and Dr Ashwin Rajagopalan. Read more

Investigating the effects of inflamm-aging on the safety and efficacy of monoclonal antibody based therapies

Our understanding of the immune response in the elderly is still in its infancy. Now, more than ever we need to understand the basic principles of immune response as the environment alters our immune system and the particles it sees. Read more

Investigating light-activated therapeutic compounds as antifungal agents

Fungal diseases are responsible for more than 1.5 million deaths and affect over a billion people worldwide. Systemic fungal infections are intrinsically difficult to treat as there are limited classes of antifungal drugs and resistance to these agents is increasing rapidly. Read more

Control of protein self assembly by biological ions

In addition to being an energy source in biological reactions, recent discoveries suggest adenosine triphosphate (ATP) also plays a critical role in maintaining cell stability and preventing deleterious cellular processes through modulating biomacromolecular self assembly. Read more

Applications of AI in drug design

Artificial Intelligence is rapidly becoming the default in modern drug design. We seek to develop new methods and applications to invent new pharmaceuticals initially for applications in Anti-ageing. Read more

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