University of East Anglia Featured PhD Programmes
Engineering and Physical Sciences Research Council Featured PhD Programmes
University of Nottingham Featured PhD Programmes
United Kingdom ×
10 miles

Pharmaceutical / Medicinal Chemistry PhD Projects, Programs & Scholarships in the UK

We have 87 Pharmaceutical / Medicinal Chemistry PhD Projects, Programs & Scholarships in the UK

  • Pharmaceutical / Medicinal Chemistry×
  • United Kingdom×
  • clear all
Order by 
Showing 1 to 30 of 87
  Chemo-enzymatic Synthesis and Potential Applications of Novel Heterocyclic Alkaloids
  Dr H Deng, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Development of antiviral peptidomimetic enzyme inhibitors
  Dr L Trembleau, Dr H Deng
Applications accepted all year round

Funding Type

PhD Type

Coronaviruses are a large group of viruses that circulate and evolve among various animals. They can cause mild human illnesses such as the common cold or more serious respiratory diseases as seen in the recent outbreaks of SARS (2002), MERS (2012), and COVID-19 (2019).
  Discovery of novel pharmaceuticals from marine and desert microorganisms
  Prof M Jaspars, Dr R Ebel
Applications accepted all year round

Funding Type

PhD Type

Microorganisms from extreme environments such as the deep seas, cold seas and hyper arid deserts have been shown to produce a range of complex natural products with high biological activity.
  New Products from a Sustainable Ammonia Cycle
  Dr M J Plater, Dr W T A Harrison
Applications accepted all year round

Funding Type

PhD Type

Renewable sources of energy are essential for the world to improve its carbon footprint and to become carbon neutral. Solar power and wind are of increasing interest particularly in hot country’s with large areas of land for solar panels.
  Toward developing next-generation therapeutics - targeting the undruggable interactome
  Dr W Houssen, Prof M Jaspars, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

Cyclic and modified cyclic peptides are very appealing scaffolds especially as therapeutics with several examples reach the clinic e.g.
  Development of Nano-Enabled Drug Carriers to Overcome Pan-Chemoresistance of Cancer Stem(-like) Cells
  Dr M Najlah
Applications accepted all year round

Funding Type

PhD Type

The acquired resistance induced by repetitive exposure of cancer cells to anticancer drugs is one of the major limitations to successful chemotherapy.
  EPSRC DTP Hub – Biosensors and Diagnostics

Funding Type

PhD Type

Cardiff University has established a new interdisciplinary training hub (IDTH) for a postgraduate student training and research program that addresses the urgent need for state-of-the-art biosensors and diagnostics.
  Discovery of novel cancer immunotherapeutic agents
  Dr Y Mehellou
Applications accepted all year round

Funding Type

PhD Type

Although cancer therapeutics, mainly chemotherapy and radiotherapy, have been extremely useful in the treatment of cancer, this disease is still associated with high morbidity and mortality.
  Microalgae as an alternative for antimicrobial resistance pressure reduction
  Dr A Escudero
Application Deadline: 2 June 2020

Funding Type

PhD Type

This project is one of 16 four year PhD Studentships funded by Medical Research Scotland (https://www.medicalresearchscotland.org.uk) to be delivered jointly by the named University and External Partner Organisation (EPO).
  Fundamentals of the Chromatographic Separation Processes of Peptide Therapeutics
  Prof D Williams
Applications accepted all year round

Funding Type

PhD Type

Imperial College are inviting applications for a PhD position to join an exciting new Engineering and Physical Sciences Research Council (EPSRC) Prosperity Partnership between Imperial, UCL and Eli Lilly on Transforming synthetic drug manufacturing.
  Solubility and Crystallisation of Peptides
  Dr J Heng
Applications accepted all year round

Funding Type

PhD Type

Imperial College are inviting applications for a PhD position to join an exciting new Engineering and Physical Sciences Research Council (EPSRC) Prosperity Partnership between Imperial, UCL and Eli Lilly on Transforming synthetic drug manufacturing.
  PhD in Continuous Manufacturing and Advanced Crystallisation

Funding Type

PhD Type

Delivering the next generation of highly skilled researchers and future workforce that will drive the transformation of continuous manufacturing.
  Carbon nanotubes in the boron neutron capture therapy of cancer
  Dr G Calabrese
Applications accepted all year round

Funding Type

PhD Type

The early promise of boron neutron capture therapy as a method for the treatment of brain cancer has been mainly inhibited by the inherent toxicity associated with 10B-containing pharmacophores and the need for the ability to cross biological membranes.
  Comparative genomic analysis of variant features within the Neisseria spp.
  Dr L Snyder
Applications accepted all year round

Funding Type

PhD Type

The availability of rapid genome sequencing had generated an explosion of bacterial genome sequence data, much of which has not been fully explored and investigated.
  Design and synthesis of novel iron chelators as a therapy for thalassaemia patients.
  Dr S Wren, Dr J Barker, Prof R Singer
Applications accepted all year round

Funding Type

PhD Type

Iron overload can be a huge issue for people coping with thalassaemia. This project will involve the synthesis of novel ion chelators that are effective and ultimately exhibit less side-effects of existing treatments.
  Investigating the chemistry of antioxidants and polysaccharides present in date-fruit (Phoenix dactylifera) as a novel/potential therapies for neoplastic and infectious diseases.
  Dr H Morgan
Applications accepted all year round

Funding Type

PhD Type

Date-fruit contains vast amount of phenols; approx. 80400µmol/100g, which portray antioxidant abilities.
  Synthesis of a toolbox of bioisosteric building blocks for drug discovery
  Dr S Wren
Applications accepted all year round

Funding Type

PhD Type

This project involves the preparation of important building blocks that feature bioisosteres (for application in various medicinal chemistry contexts).
  Developing effective measurement techniques for the assessment of Furan Fatty Acids levels
  Dr M Kimber
Application Deadline: 31 July 2020

Funding Type

PhD Type

The Furan Fatty Acids (FFAs) are an important class of natural products due to their nutritional health benefits and impact on inflammatory & cardiovascular…
  Novel Cyclic Peptides for Biomedical Imaging and Therapeutic Targeting
  Prof M Zanda
Application Deadline: 1 September 2020

Funding Type

PhD Type

Cyclic Peptides have a wide range of applications as drugs and diagnostics, and have often higher receptor affinity, metabolic stability and better pharmacokinetic properties compared to their linear counterparts, but their synthesis still presents significant challenges.
  PhD in Continuous Manufacturing and Advanced Crystallisation

Funding Type

PhD Type

Delivering the next generation of highly skilled researchers and future workforce that will drive the transformation of continuous manufacturing.
  Cascade Photoredox Reactions of Strained, Two Carbon Building-Blocks: One-Pot Synthesis of Complex, Bioactive Molecules (Ref: SF20/APP/KNOWLES)
  Dr J Knowles
Applications accepted all year round

Funding Type

PhD Type

Developing access to new molecules is a key objective for chemists, particularly to three-dimensional, sp3-rich compounds which show improved bioactivity compared with flatter structures favoured by recent strategies within the pharmaceutical sector.
  Iontophoresis to deliver corticosteroids across buccal mucosal using hydrogel as delivery systems
  Prof M Patel, Dr E Hagi-Pavli
Applications accepted all year round

Funding Type

PhD Type

Background. Topical delivery of drugs to treat oral mucosal disease is often challenging. This is due to, for example, the saliva washing therapeutic agents away into the gastrointestinal system, the movement of oral structures during mastication and the presence of keratinized oral mucosal surfaces.
  Reversing multidrug chemoresistance in head and neck cancer
  Dr M T Teh
Applications accepted all year round

Funding Type

PhD Type

Background. Multidrug resistance renders chemotherapeutic treatment failure in large proportion of head and neck squamous cell carcinoma (HNSCC) patients requiring multimodal therapy involving chemotherapy in conjunction with surgery and/or radiotherapy.
  Computer Simulations of G protein-coupled Receptors
  Dr I Tikhonova
Applications accepted all year round

Funding Type

PhD Type

Many physiological processes are controlled through the activation of G protein-coupled receptors (GPCRs) by regulatory peptides, making peptide GPCRs particularly useful targets for major human diseases such as diabetes and CNS diseases.
  Microfabricated Engineered Systems for Sustained Ocular Drug Delivery
  Dr R Thakur, Dr D Lamprou
Applications accepted all year round

Funding Type

PhD Type

Retinal diseases that originate at the back of the eye, such as Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME), represent the leading causes of vision loss in the Western world.
  Microfluidic Synthesis of Nanomedicines for the Delivery of Biologic Drugs
  Dr D Lamprou
Applications accepted all year round

Funding Type

PhD Type

Progress in drug design has led to the development of new molecules. However, the limited ability to selectively deliver these molecules at well-defined dosing regimens remains a significant challenge.
  Peptide hydrogels as a long-acting multipurpose drug delivery platform for combined contraception and HIV prevention
  Dr G Laverty, Prof K Malcolm
Applications accepted all year round

Funding Type

PhD Type

HIV/AIDS is the leading cause of death in women of reproductive age worldwide. HIV and unintended pregnancies are prevalent in developing nations due to the lack of effective female contraceptive choice.
  Peptide hydrogels as novel nanotherapeutic delivery agents enhancing the anti-tumour efficacy of radiotherapy
  Dr J Coulter, Dr G Laverty
Applications accepted all year round

Funding Type

PhD Type

There is a pressing clinical need for effective localised cancer treatments. Addressing this need we will develop a novel drug delivery system comprised of a nanoparticle/drug releasing hydrogel implant.
  Responsive hydrogel platforms towards the prevention of medical device-associated infections
  Dr N Irwin, Dr C McCoy
Applications accepted all year round

Funding Type

PhD Type

Catheter-associated urinary tract infections represent a high priority global healthcare challenge. We have recently identified a suite of non-antibiotic active agents with promising antibacterial and anti-encrustation activities.
  Surface-modified silicone elastomer for medical and drug delivery devices with reduced bacterial adherence and biofilm formation
  Dr L Carson, Prof K Malcolm
Applications accepted all year round

Funding Type

PhD Type

All implanted medical devices, including those fabricated from silicone elastomers, are susceptible colonisation with communities of microorganisms that colonise the surface of the device and rapidly establish biofilm populations.
Show 10 15 30 per page


FindAPhD. Copyright 2005-2020
All rights reserved.