Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

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Mechanically Interlocked Ligands for Medical Imaging

University of Birmingham School of Chemistry

Background – metal coordination and the mechanical bond. Read more

Supervisor: Prof S Goldup

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Pectin supplementation to reduce gut and systemic inflammation and improve liver, muscle and gastrointestinal outcomes

University of Nottingham School of Medicine

A quarter of the world's population has metabolic dysfunction-associated steatotic liver disease, (which used to be known as non-alcoholic fatty liver disease). Read more

Supervisors: Prof G Aithal, Dr J Grove, Dr KR Rollins, Prof AMV Valdes

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry

Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more

Supervisors: Prof E Takano, Prof H Oguri

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Elucidating the role of lipids in fibrotic capsule formation at the surface of implanted medical devices.

University of Nottingham School of Medicine

Implanted medical devices are crucial in healthcare, valued at around £400 billion globally, however there is a high failure rate, often due to the foreign body reaction, where a fibrotic capsule forms around the implant with associated inflammation, loosening and infection. Read more

Supervisors: Prof M Alexander, Prof AG Ghaemmaghami, Dr D H Kim, Prof BO Ollivere

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Application of Thermally Stimulated Current (TSC) Spectroscopy for Qualitative and Quantitative Characterisation of Amorphous Pharmaceutical Systems

University of Surrey School of Chemistry and Chemical Engineering

This project is funded by iCase EPSRC – AstraZeneca. The PhD student will be required to spend some time at AstraZeneca conducting part of the training and research relevant to the project. . Read more

Supervisors: Dr M Antonijevic, Dr D Watson

1 July 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Protein self assembly induced by multivalent biological metabolites

The University of Manchester Department of Chemical Engineering

In addition to being an energy source in biological reactions, recent discoveries suggest adenosine triphosphate (ATP) also plays a critical role in maintaining cell stability and preventing deleterious cellular processes through modulating biomacromolecular self assembly. Read more

Supervisor: Dr R Curtis

31 December 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Crystal engineering new, more effective medicines.

Newcastle University School of Pharmacy

BACKGROUND. Neglected Tropical Diseases (NTDs) – a diverse group of infectious diseases – continue to thrive across low- income populations. Read more

Supervisor: Dr O Kavanagh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Quantifying the risk of precipitating drug induced crystalluria (XTALURIA)

Newcastle University School of Pharmacy

The growth of crystals in the body often results in pain, damage, and gross harm. Read more

Supervisor: Dr O Kavanagh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Inflammatory Arthritis in Childhood: Impact, Outcomes and Safety of Treatment

The University of Manchester Faculty of Biology, Medicine and Health

Juvenile Idiopathic Arthritis is the most common inflammatory arthritis of childhood. Although less common than arthritis in adults, a diagnosis of arthritis in a child can have lasting impacts on that child and their families through their entire lifespan. Read more

Supervisors: Prof K Hyrich, Dr L Kearsley-Fleet

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Myelodysplastic syndromes (MDS) are a type of blood cancer where the patients do not have enough healthy blood cells. Read more

Supervisors: Dr T Nasim, Dr M Najafzadeh

Year round applications PhD Research Project Self-Funded PhD Students Only

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New Drugs for Brain Tumours: Prodrugs of Diazopropyne

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identifying cognitive and biochemical changes underlying lifestyle risk factors for dementia

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Dementia describes a group of age-associated conditions of which cognitive decline is a major feature. Alzheimer’s disease (AD) is the most common cause of dementia and is characterised by the onset of a gradual cognitive decline. Read more

Supervisors: Dr S McLean, Dr R Williamson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Directed Co-Crystallisation of Pharmaceuticals: developing a predictive method for co-crystallisation

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

In this project, we propose to use a combination of computational and experimental techniques to develop a predictive method for co-crystallisation. Read more

Supervisor: Dr C Seaton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Supervisors: Prof R Falconer, Prof P Loadman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

Supervisors: Prof R Falconer, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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Biological rhythms and the dopamine system in cognitive dysfunction

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Psychiatric disorders such as schizophrenia are associated with metabolic syndrome, obesity and diabetes. Schizophrenia affects 1.1% of the population and although not the most common psychiatric condition it is arguably the most severe and debilitating. Read more

Supervisors: Dr S McLean, Dr G Helfer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Therapeutic resolution of BMPR2-mediated signalling defects in pulmonary arterial hypertension (PAH)

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Pulmonary arterial hypertension (PAH) is an incurable and devastating disease and death occurs within 2.5 years of diagnosis. Read more

Supervisors: Dr T Nasim, Dr R Gopalan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Non-thermal plasma as a chemical reagent: elucidating mechanism and exploring NTP for pharmaceutically relevant electroreductive reactions

University of Liverpool Department of Chemistry

Chemistry depends on electrons, but we cannot yet fully control electrons to deliver precise reactivity. Controlled high-energy electron sources—such as non-thermal plasma (NTP)—could unlock new and selective chemical transformations, but little is known about these states of matter when mixed with reaction media. Read more

Supervisors: Dr A Slater, Dr C Aissa

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Enhancing Flexibility and Resilience in Vaccine Supply Chains through Modelling and Optimisation

University of Sheffield Department of Chemical & Biological Engineering

This PhD project aims to advance the flexibility and resilience of vaccine supply chains, focusing on challenges from emerging infectious diseases and the urgent need for rapid vaccine development and distribution. Read more

Supervisors: Prof A Tiwari, Prof A Brintrup

30 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Engineering Virus-Like Particles for Next-Generation Vaccine Manufacturing

University of Sheffield Department of Chemical & Biological Engineering

Virus-like particles (VLPs) are structures typically composed of viral structural proteins that self-assemble into virus-like structures. Read more

Supervisors: Dr K Tee, Prof TS Wong, Dr C Evans

30 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Using Data-Driven and Knowledge-Informed Modelling to Improve Vaccine Manufacturing

University of Sheffield Department of Chemical & Biological Engineering

This PhD will use modelling tools to predict and improve the quality, cost and reliability of vaccine or other pharmaceutical processes. Read more

Supervisors: Prof J Cordiner, Dr Z Kis

30 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Inorganic chaperones fused to fungal derived chemotherapeutic agents for the treatment of neuroblastoma

University of Salford School of Science, Engineering and Environment

Information on this PhD research area can be found further down this page under the details about the Widening Participation Scholarship given immediately below. Read more

Supervisors: Dr R Arrigo, Dr S Namvar

Year round applications PhD Research Project Self-Funded PhD Students Only

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Breaking the resistance: alternative approaches to antibiotics discovery

Queen’s University Belfast School of Pharmacy

The World Health Organisation (WHO) identifies antimicrobial resistance (AMR) as one of the top 10 global threats to human health (http://www.who.int/). Read more

Supervisor: Prof G Wagner

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of Sustainable Systems for the Removal of Antibiotics Traces from Biological and Environmental Media to Tackle Antimicrobial Resistance

Kingston University Faculty of Health, Science, Social Care and Education

Antimicrobial resistance (AMR) is a grave threat to public health that humankind must urgently resolve. If no if no action is taken by 2050, AMR can cause millions of deaths. Read more

Supervisor: Dr M Khoder

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Breaking the resistance: alternative approaches to antibiotics discovery

Queen’s University Belfast School of Pharmacy

The World Health Organisation (WHO) identifies antimicrobial resistance (AMR) as one of the top 10 global threats to human health (http://www.who.int/). Read more

Supervisor: Prof G Wagner

Year round applications PhD Research Project Self-Funded PhD Students Only

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Harnessing Breast Cancer Therapy: Innovative Formulation Strategies for Repurposing Medicines to Overcome Resistance

Kingston University Faculty of Health, Science, Social Care and Education

Background. Research in the Kadri group focuses on developing innovative chemical approaches for the discovery of novel therapeutics to address unmet global health needs. Read more

Supervisor: Dr H Kadri

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design and study of modified peptide foldamers

Aberdeen University School of Natural and Computing Sciences

These projects are open to students worldwide, but have no funding attached. Therefore, the successful applicant will be expected to fund tuition fees at the relevant level (home or international) and any applicable additional research costs. Read more

Supervisors: Dr L Trembleau, Dr H Deng

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery of novel pharmaceuticals from marine and desert microorganisms

Aberdeen University School of Natural and Computing Sciences

These projects are open to students worldwide, but have no funding attached. Therefore, the successful applicant will be expected to fund tuition fees at the relevant level (home or international) and any applicable additional research costs. Read more

Supervisors: Prof M Jaspars, Dr R Ebel

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 111 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

We have 111 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

Mechanically Interlocked Ligands for Medical Imaging

Pectin supplementation to reduce gut and systemic inflammation and improve liver, muscle and gastrointestinal outcomes

(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

Elucidating the role of lipids in fibrotic capsule formation at the surface of implanted medical devices.

Application of Thermally Stimulated Current (TSC) Spectroscopy for Qualitative and Quantitative Characterisation of Amorphous Pharmaceutical Systems

Protein self assembly induced by multivalent biological metabolites

Crystal engineering new, more effective medicines.

Quantifying the risk of precipitating drug induced crystalluria (XTALURIA)

Inflammatory Arthritis in Childhood: Impact, Outcomes and Safety of Treatment

Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

Identifying cognitive and biochemical changes underlying lifestyle risk factors for dementia

Directed Co-Crystallisation of Pharmaceuticals: developing a predictive method for co-crystallisation

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

Biological rhythms and the dopamine system in cognitive dysfunction

Therapeutic resolution of BMPR2-mediated signalling defects in pulmonary arterial hypertension (PAH)

Non-thermal plasma as a chemical reagent: elucidating mechanism and exploring NTP for pharmaceutically relevant electroreductive reactions

Enhancing Flexibility and Resilience in Vaccine Supply Chains through Modelling and Optimisation

Engineering Virus-Like Particles for Next-Generation Vaccine Manufacturing

Using Data-Driven and Knowledge-Informed Modelling to Improve Vaccine Manufacturing

Inorganic chaperones fused to fungal derived chemotherapeutic agents for the treatment of neuroblastoma

Breaking the resistance: alternative approaches to antibiotics discovery

Development of Sustainable Systems for the Removal of Antibiotics Traces from Biological and Environmental Media to Tackle Antimicrobial Resistance

Breaking the resistance: alternative approaches to antibiotics discovery

Harnessing Breast Cancer Therapy: Innovative Formulation Strategies for Repurposing Medicines to Overcome Resistance

Design and study of modified peptide foldamers

Discovery of novel pharmaceuticals from marine and desert microorganisms

We have 111 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

We have 111 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships in the UK

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