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Pharmaceutical / Medicinal Chemistry PhD Projects, Programs & Scholarships in the UK

We have 111 Pharmaceutical / Medicinal Chemistry PhD Projects, Programs & Scholarships in the UK

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We have 111 Pharmaceutical / Medicinal Chemistry PhD Projects, Programs & Scholarships in the UK

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Catalytic Asymmetric ‘Clip-Cycle’ Reactions: Synthesis of Heterocycles Important in Drug Discovery

Cyclic ethers and amines are ubiquitous in biologically active natural and non-natural products. However, despite this prevalence and importance, there is no strategy for their asymmetric synthesis which is independent of heteroatom and/or ring size. Read more

Stabilizers of the interaction between 14-3-3 and hDM2/hDMX

  Research Group: School of Chemistry
Transient protein-protein interactions (PPIs) control all cellular processes relevant to health and disease. Selective modulation of individual PPIs would thus facilitate both a greater understanding of biological mechanisms and provide new opportunities for therapeutic intervention. Read more

Development and validation of techniques bridging cell culture and/or reconstructed skin models and human clinical testing

This is a four-year PhD project sponsored by the BBSRC and Glaxo Smith Kline, UK. The UCL Skin and Buccal research has a strong track record in the development and validation of ex vivo models for delivery of actives in humans. Read more

Understanding effects of formulations on ingredient interactions with oral buccal tissue

This is a four-year PhD project sponsored by the BBSRC and Glaxo Smith Kline, UK. This PhD project aims to investigate the effects of specific excipients on the delivery of a range actives to oral mucosal tissue. Read more

The Influence of hybrid nanoparticle architecture on theranostic abilities in pancreatic cancer

We are looking to recruit a PhD student with a relevant chemical, pharmaceutical, biomedical science or bioengineering background to design and develop novel nanomedicine platforms for chemotherapy. Read more

Fragment-Based Lead Generation of Small Molecule Inhibitors of the Nsp3 Macrodomain in SARS-CoV-2 – Towards New Antivirals for the Treatment of COVID-19

Supervisors. Peter O’Brien (University of York), Ivan Ahel (Sir William Dunn School of Pathology, University of Oxford) and Frank von Delft (Diamond Light Source, XChem screening facility and Centre for Medicines Discovery, University of Oxford). Read more

Plug-and-play discovery of molecular glues: a new drug discovery paradigm

Bifunctional drugs and molecular glues are emerging as powerful drug modalities with the potential to transform treatment of currently intractable diseases by targeting so-called 'undruggable' proteins. Read more

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