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Pharmacology / Toxicology PhD Projects, Programs & Scholarships in the UK

We have 116 Pharmacology / Toxicology PhD Projects, Programs & Scholarships in the UK

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Showing 1 to 30 of 116
  Images in the medical and life sciences
  Dr U Stegmann, Dr L Moretti
Applications accepted all year round

Funding Type

PhD Type

Pictorial representations and images (e.g. photographs and diagrams) are common in the medical and life sciences. Examples include fMRI images and micrographs.
  Development of ex vivo tissue culture models for developing next-generation biomaterial scaffolds for acellular regenerative medicine.
  Prof I Gibson, Prof N Vargesson
Applications accepted all year round

Funding Type

PhD Type

Bone repair and regeneration can be influenced by various guidance cues, including pharmacological cues, hypoxia environment and chemical cues released from scaffolds [1-3].
  EPSRC Centre for Doctoral Training in Engineered Tissues for Discovery, Industry and Medicine (LifETIME)

Funding Type

PhD Type

The CDT will train the next generation of leaders in developing in vitro tissues, sensing and diagnostics to develop humanised in vitro systems to drive better drug screening.
  Disrupting the regulatory mechanisms that allow hospital acquired infections to resist antibiotic therapy.
  Dr R McCarthy
Applications accepted all year round

Funding Type

PhD Type

The discovery of penicillin over 90 years ago and its subsequent uptake by healthcare systems around the world revolutionised global health and wellbeing.
  Inhibiting cell metabolism to enhance tumour cell death
  Dr C Bubici, Dr S Papa
Application Deadline: 31 January 2020

Funding Type

PhD Type

As you read this, millions of your cells from your body are dying. Do not panic – this is not bad news. Most of them are either superfluous or potentially harmful, so you are better off without them.
  Nanoparticles in drug delivery
  Dr G Stenbeck, Dr U Kishore
Applications accepted all year round

Funding Type

PhD Type

Nanoparticles (NPs) are materials with overall dimensions in the nano scale range (5nm-100nm). Due to their unique physicochemical properties, they have found a wide range of applications and are currently explored as drug and gene delivery vehicles.
  Telomere length elongation following treatment with chemotherapeutic drugs. Aim: To investigate the mechanisms which leads to telomere length elongation after treatment with tricostatin A and azacytidine.
  Dr T Roberts
Applications accepted all year round

Funding Type

PhD Type

Telomeres are specialised structures, which are present at the ends of chromosomes and serve to protect the chromosome from degradation during cell division.
  Discovering zinc signalling mechanisms to prevent breast cancer progression
  Dr K Taylor
Applications accepted all year round

Funding Type

PhD Type

Zinc is essential for all living cells, yet the true extent of its role is only now emerging and is fully suggestive of a complexity and importance of that attributed to calcium.
  Discovery of novel cancer immunotherapeutic agents
  Dr Y Mehellou
Applications accepted all year round

Funding Type

PhD Type

Although cancer therapeutics, mainly chemotherapy and radiotherapy, have been extremely useful in the treatment of cancer, this disease is still associated with high morbidity and mortality.
  Discovery of novel treatments for Parkinson’s disease
  Dr Y Mehellou, Dr E Lane
Applications accepted all year round

Funding Type

PhD Type

Parkinson’s disease (PD) is the second most common neurological disease in the world. Current PD therapies and medical interventions are very limited and only address the symptoms of this disease highlighting the need for new and effective treatments.
  PhD in Continuous Manufacturing and Advanced Crystallisation

Funding Type

PhD Type

CMAC, the EPSRC Future Manufacturing Research Hub in Continuous Manufacturing and Advanced Crystallisation, is a major initiative that aims to accelerate the adoption of continuous manufacturing technologies for high value chemical products such as pharmaceuticals.
  EPSRC Centre for Doctoral Training (CDT) in Smart Medical Imaging

Funding Type

PhD Type

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  EPSRC Centre for Doctoral Training (CDT) in Smart Medical Imaging

Funding Type

PhD Type

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  Synthesis and Anti-Cancer Evaluation of New Heterocyclic Quinones
  Prof F Aldabbagh, Dr N Hill
Applications accepted all year round

Funding Type

PhD Type

The group has published on small molecules with specificity towards hypoxic cells associated with solid tumours, reductase enzymes over-expressed in cancer, as well as, aziridines that induce hypersensitivity from Fanconi anaemia cells and those carrying mutations in the BRCA (Breast Cancer Susceptibility) genes.
  Synthesis and identification of homoisoflavonoids and lignans for the treatment of wet active age-related macular degeneration based on their anti-vascular endothelial growth factor and anti-inflammatory activities
  Dr S Schwikkard, Dr E Opara
Applications accepted all year round

Funding Type

PhD Type

Age-related macular degeneration is reported to be the most common cause of visual impairment, and its certification, in the developed world.
  The influence of psychological stress on health and physical performance in British Army Recruits
  Prof N Walsh
Application Deadline: 30 September 2019

Funding Type

PhD Type

PhD Studentship (4 years). Applications are invited for a four-year, full-time PhD studentship supervised by Prof Neil Walsh and his team in the School of Sport and Exercise Sciences, Liverpool John Moores University.
  PhD in Continuous Manufacturing and Advanced Crystallisation

Funding Type

PhD Type

CMAC, the EPSRC Future Manufacturing Research Hub in Continuous Manufacturing and Advanced Crystallisation, is a major initiative that aims to accelerate the adoption of continuous manufacturing technologies for high value chemical products such as pharmaceuticals.
  Pre-clinical targets for vascular dementia treatment
  Prof R Fern, Dr E Kramer, Dr K Glebov
Application Deadline: 6 October 2019

Funding Type

PhD Type

MPhil/PhD Studentship available full time and part-time. Project title. Pre-clinical targets for vascular dementia treatment. Reference Number.
  Modelling of Oral Neutrophil Epithelial interactions
  Dr E Hagi-Pavli
Applications accepted all year round

Funding Type

PhD Type

Background and Clinical Significance. Neutrophils are an important and vital cellular component of the innate immune system providing rapid protection against microbial invasion.
  Biomedical research in a simple non-animal model
  Prof R S B Williams
Applications accepted all year round

Funding Type

PhD Type

Research in biomedical neuroscience generally employs mammalian tissue culture experiments to look at disease-related neuronal cell function.
  Molecular Pharmacology of N-Methyl-D-aspartate glutamate receptors
  Dr P Chen
Applications accepted all year round

Funding Type

PhD Type

Fast neuronal communication at synaptic contacts relies on neurotransmitter release from the presynaptic terminal and the majority of excitatory neurotransmission within the mammalian central nervous system is mediated by the neurotransmitter glutamate.
  Mucosal Vaccines - using Bacillus subtilis spores to develop vaccines and adjuvants against disease
  Prof S Cutting
Applications accepted all year round

Funding Type

PhD Type

Heat stable bacterial spores are being used as novel mucosal vaccines. Spores of Bacillus subtilis have been used successfully as both vaccines and adjuvants against a number of diseases.
  Stimuli-responsive biopolymers for life science, materials and therapeutic applications
  Dr M Soloviev
Applications accepted all year round

Funding Type

PhD Type

This is a self-funded project, match-finding option may be available for qualifying candidates. Please include a detailed CV with any enquiries.
  Identification of mechanisms underlying atrial fibrillation and effective therapies
  Dr X Wang, Dr V Liu
Applications accepted all year round

Funding Type

PhD Type

Atrial fibrillation (AF) is the most common cardiac arrhythmia in clinical practice with particular high prevalence in aged populations.
  Maternal anti-hypertensive medicines & placental vascular function
  Dr P Brownbill, Dr J Myers, Dr E Johnstone
Applications accepted all year round

Funding Type

PhD Type

A range of anti-hypertensive medicines are prescribed to women with chronic hypertension in pregnancy, that enter the fetal circulation.
  Control of Parathyroid Hormone Secretion
  Dr D Ward, Dr J Bruce
Applications accepted all year round

Funding Type

PhD Type

The regulation of parathyroid hormone (PTH) secretion is of fundamental importance for calcium homeostasis and in mineral conditions affecting bone and the kidneys.
  Epigenetic mechanisms of behavioural, placental and cognitive impairment in a neurodevelopmental model for schizophrenia
  Dr R Hager, Prof J Neill, Dr J Glazier
Applications accepted all year round

Funding Type

PhD Type

A fundamental question in disease research is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016).
  Using synthetic biology to understand the evolution of antibiotic resistance
  Dr M Lagator, Dr C Knight
Applications accepted all year round

Funding Type

PhD Type

Imagine an architect, tasked with converting an old stadium into a building with a different function, without demolishing it.
  Exploring the influence of proteogenomics in patients receiving biologic drugs for treatment of psoriatic arthritis
  Prof A Barton, Dr James Bluett, Dr N Nair
Applications accepted all year round

Funding Type

PhD Type

Background. Psoriatic arthritis (PsA) is an inflammatory arthritis, associated with the chronic skin condition psoriasis, which causes joint inflammation.
  Exploring the influence of treatment on CD4+ T-cell sub-populations in patients receiving biologic drugs for their inflammatory arthritis
  Prof A Barton, Dr D Plant, Dr S Viatte
Applications accepted all year round

Funding Type

PhD Type

Background. Tumour necrosis factor inhibitor (TNFi) therapy is ineffective for approximately 20% of rheumatoid arthritis (RA) patients and there is currently no way to predict which patients will not benefit.
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