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We have 163 Pharmacology PhD Projects, Programmes & Scholarships in the UK

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Pharmacology PhD Projects, Programmes & Scholarships in the UK

We have 163 Pharmacology PhD Projects, Programmes & Scholarships in the UK

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Designing next-generation urinary catheter materials for clean intermittent self-catheterisation through control of the urinary microbiome

Queen’s University Belfast School of Pharmacy
Intermittent urinary catheterisation is commonly used to address chronic urinary retention in patients suffering from conditions such as spinal cord injury, stroke, and multiple sclerosis. Read more
 Supervisors: Dr M Wylie, Dr L Sherrard
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of carbohydrate-functionalised materials for detection and prevention of medical device-associated infections

Queen’s University Belfast School of Pharmacy
Antibiotic-resistant bacteria are a growing problem in the 21st century, causing longer and more serious infections, and resulting in poor outcomes for vulnerable patients. . Read more
 Supervisor: Dr M Wylie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Microneedle delivery systems for minimally-invasive patient diagnosis/monitoring

Queen’s University Belfast School of Pharmacy
In this project, a novel type of integrated system will be investigated that will by-pass the skin barrier. On its surface will be multiple microscopic needles that pierce the skin without causing any pain – the sensation is said to feel like a cat’s tongue or sharkskin. Read more
 Supervisor: Prof R Donnelly
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Microneedle delivery systems for next-generation antibody therapeutics

Queen’s University Belfast School of Pharmacy
Microneedle arrays are minimally-invasive devices that painlessly, and without drawing blood, penetrate the skin’s stratum corneum barrier. Read more
 Supervisor: Prof R Donnelly
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Does one size fit all for antimicrobial delivery via nanoparticles

Queen’s University Belfast School of Pharmacy
Antimicrobial resistant bacteria are a growing problem and new ways are needed to target bacterial infections more efficiently. One way in which bacteria can avoid therapeutics is via intracellular infection, where they hide within our own cells. Read more
 Supervisors: Dr J Burrows, Prof B Gilmore
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Regulation of CaaX protein processing

Queen’s University Belfast School of Pharmacy
USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and its depletion has been shown to block the growth of cells from all these cancer types, as well as the migration of a range of cancer cells (NSCLC, breast, ovarian, osteosarcoma).    . Read more
 Supervisor: Dr J Burrows
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of carers in medicines management for people living with dementia

Queen’s University Belfast School of Pharmacy
It is estimated that there are close to 50 million people living with dementia worldwide, and this number is estimated to double every 20 years. Read more
 Supervisors: Dr H Barry, Prof C Hughes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

University of Liverpool Department of Pharmacology and Therapeutics
Liver sinusoidal endothelial cells (LSECs) comprise approximately 50% of the non-parenchymal hepatic cells. They play a vital role in hepatic microcirculation and provide a physiological barrier to the movement of xenobiotics from the bloodstream to hepatic tissue. Read more
 Supervisors: Dr M Cross, Prof C Goldring
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Queen’s University Belfast School of Pharmacy
Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more
 Supervisors: Dr I Tikhonova, Dr B Plouffe
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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High throughput exploration of the design space for antifungal nanocarrier development

Queen’s University Belfast School of Pharmacy
Fungal and bacterial infections contribute to over 7 million deaths yearly, affecting over 300 million people globally (GAFFI). Read more
 Supervisor: Dr J Tian
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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A systematic screening tool for nanocarrier design and efficient drug delivery against biological barriers.

Queen’s University Belfast School of Pharmacy
Encapsulation of APIs in a liposome can dramatically alter the distribution by controlling the release to normal tissue while facilitating the accumulation to the site of inflammation. Read more
 Supervisor: Dr J Tian
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Designing and evaluating novel nanotherapeutics to enhance the effectiveness of radiotherapy in the treatment of solid cancers.

Queen’s University Belfast School of Pharmacy
One in two cancer patients will receive radiotherapy as part of their treatment. For patients with a localised cancer diagnosis effective radiotherapy represents the best chance of a curative outcome, however, is not without risk. Read more
 Supervisor: Dr J Coulter
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Synthetic Protein-Transporters for Enhanced Transduction Activity

Queen’s University Belfast School of Pharmacy
Intracellular protein delivery is key to probing important cellular processes and developing advanced biotherapeutics. However, protein trafficking into the cell, and more specifically to the cytosol remains a significant challenge. Read more
 Supervisor: Dr S Carmali
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Queen’s University Belfast School of Pharmacy
Cystic fibrosis (CF) is a progressive life-limiting airways disease that affects over 162,000 people worldwide. Read more
 Supervisor: Prof L Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Selective targeting of furin for the treatment of fibrotic lung disease.

Queen’s University Belfast School of Pharmacy
Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more
 Supervisor: Prof L Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Peptide-based nanoparticles for brain targeted gene delivery.

Queen’s University Belfast School of Pharmacy
Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases and cancer. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site. Read more
 Supervisors: Dr E McErlean, Prof H McCarthy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genetic Engineering of Immune Effector Cells for CAR therapies using a Peptide Technology

Queen’s University Belfast School of Pharmacy
Chimeric antigen receptor (CAR)-T therapies have demonstrated remarkable treatment outcomes and several CAR-T therapies now approved for treatment of haematological malignancies. Read more
 Supervisors: Dr E McErlean, Prof H McCarthy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing novel therapeutic strategies to better treat Triple Negative Breast Cancer

Queen’s University Belfast School of Pharmacy
One in two people will develop cancer in their lifetime and it is a leading cause of death.  While significant progress has been made in the treatment of some cancers, there still remain some forms of the disease with limited treatment options and poor outcome. . Read more
 Supervisor: Dr N Buckley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Drug repurposing for the treatment of aspergillosis

The University of Manchester Faculty of Biology, Medicine and Health
The mould Aspergillus fumigatus was classified by the WHO as a critical priority pathogen in 2022. It causes a spectrum of invasive, allergic and chronic disease. Read more
 Supervisors: Dr CK Kosmidis, Prof D Ashcroft, Dr M Bottery, Dr M Bromley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Freeze-dried bacteriophage formulations against antibiotic-resistant bacteria

Queen’s University Belfast School of Pharmacy
Antimicrobial resistance (AMR) presents a significant global public health issue. Read more
 Supervisors: Dr T Skvortsov, Prof K Malcolm, Dr V Kett
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Tackling health inequity in pharmaceuticals

University College London UCL School of Pharmacy
Tackling health inequity in pharmaceuticals. Research has been increasingly highlighting the disparities in the investigation of gender-specific responses to medicines. Read more
 Supervisor: Prof A Basit
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

University of Liverpool Institute of Systems, Molecular and Integrative Biology
Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more
 Supervisor: Dr T You
 1 August 2024  PhD Research Project  Self-Funded PhD Students Only
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Network-based predictive modelling of cardiovascular disease risk

University of Liverpool Institute of Systems, Molecular and Integrative Biology
The risk of cardiovascular disease (CVD) is orchestrated by multiple factors. QRISK models (currently QRISK3) have been used in the UK to estimate CVD risk within the next 10 years for individuals without CVD. Read more
 Supervisor: Dr T You
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MRes in Clinical Science

University of East Anglia Norwich Medical School
Our MRes Clinical Science is your chance to experience the reality of cutting-edge clinical or biomedical research. You’ll develop a broader, more considered approach to a specific area of medical research, gaining expertise in the intellectual and practical skills of scientific research in the process. Read more
 Supervisor: Dr K Tyler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring the molecular mechanisms of skin aging process and understanding the relationship between skin aging and systemic aging

University of Nottingham School of Pharmacy
Applicants are invited for fully funded 3 years full time PhD studentships, starting from 1st February 2023, or 1st April 2023, or 1st October 2023 at latest, based in the School of Pharmacy, The University of Nottingham. Read more
 Supervisor: Dr Z Zhu
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences
Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more
 Supervisors: Dr M Young, Dr J Parker
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular mechanisms underlying the anti-atherogenic actions of natural products

Cardiff University Cardiff School of Biosciences
Atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is responsible for most deaths in the western world with mortality increasing at a marked rate in developing. Read more
 Supervisors: Dr D Ramji, Dr T Hughes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing novel treatments for invasive fungal infections

University of Strathclyde Department of Pure and Applied Chemistry
Invasive Fungal Infections. Invasive fungal infections, such as those caused by the fungi Candida, are an increasing global public health concern. Read more
 Supervisor: Dr FS Scott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Inducing ferroptotic death to kill cancer cells

The University of Manchester Faculty of Biology, Medicine and Health
Ferroptosis is an iron-dependent form of regulated necrotic cell death triggered by oxidative degradation of lipids in membrane bilayers and subsequent irreparable damages to the plasma membrane (1). Read more
 Supervisors: Dr C Tournier, Dr K Finegan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the roles that G protein coupled receptors play in hypertension

University of Leicester Molecular and Cell Biology
G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more
 Supervisor: Dr J Willets
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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