Structural Biology PhD Projects, Programmes & Scholarships in the UK

We have 108 Structural Biology PhD Projects, Programmes & Scholarships in the UK

Structural and functional characterisation of bacterial virulence factors

Kingston University Faculty of Health, Science, Social Care and Education

In the current era of growing antibiotic resistance, the world needs new therapeutics against bacterial infections as well as new vaccines. Read more

Supervisor: Dr E Lamber

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Exploiting Deep Learning-based protein structure prediction for function annotation and structural biology

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Applications will be reviewed until a suitable candidate is appointed. Protein structural information is crucial for an understanding of protein function and evolution. Read more

Supervisors: Prof D J Rigden, Dr R Keegan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Protein self assembly induced by multivalent biological metabolites

The University of Manchester Department of Chemical Engineering

In addition to being an energy source in biological reactions, recent discoveries suggest adenosine triphosphate (ATP) also plays a critical role in maintaining cell stability and preventing deleterious cellular processes through modulating biomacromolecular self assembly. Read more

Supervisor: Dr R Curtis

31 December 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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A 3D-Printed Blood-Brain-Barrier-on-a-Chip for Agrochemical Permeability Studies – CASE Studentship

University of Liverpool Department of Physics

The blood-brain barrier (BBB) tightly regulates the flow of material between the bloodstream and the brain. One of the big problems faced by a range of sectors, from pharmaceuticals to agrochemicals, is understanding how compounds interact with and cross this barrier. Read more

Supervisors: Dr J Forth, Dr D Dickens

1 June 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Structure and function of enzyme complexes involved in post-transcriptional gene regulation

University of Nottingham School of Pharmacy

Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Exploring Viral Nucleic Acid Machinery via Cryo Electron Microscopy to Advance Biomedicine

University of York York Biomedical Research Institute

Viruses, these tiny but potent life forms, are all around us, infecting various organisms and directly affecting human health. Although in most cases, viral infection is not life threatening, in the minority of cases it leads to long-term disorders including cancer. Read more

Supervisors: Prof F Antson, Dr J Gordeeva, Dr P Bardy

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

University of Leicester Molecular and Cell Biology

Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more

Supervisor: Dr G Hall

Year round applications PhD Research Project Self-Funded PhD Students Only

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The identification of allosteric inhibitors of high value therapeutic targets

University of Sheffield School of Biosciences

This study will develop a novel approach to identify allosteric inhibitor sites on a wide variety of high-value therapeutic targets, including protein kinases, protein phosphatases and small G-proteins. Read more

Supervisor: Prof J P Waltho

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural insights into genome control by cohesin

University of Leicester Molecular and Cell Biology

Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more

Supervisor: Prof D Panne

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Targeted protein degradation in plants – developing “Green PROTACs” for functional analysis of lethal genes

University of Dundee School of Life Sciences

Climate change is one of the biggest threats to global food production, leading to unpredictable weather patterns and geographical migration of pathogens. Read more

Supervisor: Dr P Hemsley

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Feel the tension – how does S-acylation of OSCA ion channels regulate responses to environmental change in plants?

University of Dundee School of Life Sciences

Plants, being sessile organisms, must sense and respond to environmental change, such as temperature or drought, without being able to move. Read more

Supervisors: Dr P Hemsley, Prof U Zachariae, Prof M Knight

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: ADP-ribosylation in dementia and motor neuron disease

University of Dundee School of Life Sciences

ADP-ribosylation is a fundamental posttranslational modification where ADP-ribose is linked on to target proteins by ADP-ribose transferases and removed by the ADP-ribose hydrolases. Read more

Supervisor: Dr L McGurk

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Deciphering the ubiquitin codes that regulate protein degradation

University of Dundee School of Life Sciences

Ubiquitin signalling, which involves the posttranslational modification (PTM) of proteins with ubiquitin, regulates almost every aspect of eukaryotic biology. Read more

Supervisor: Prof Y Kulathu

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: How are SUMO substrates selected for modification ?

University of Dundee School of Life Sciences

SUMO has diverse roles in cellular physiology that in most cases are mediated by its ability to interact non-covalently with hydrophobic patches of low sequence complexity known as SUMO Interaction Motifs (SIMs). Read more

Supervisor: Prof R Hay

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Regulation and mechanics in polarized trafficking

University of Dundee School of Life Sciences

Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more

Supervisor: Dr D H Murray

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 108 Structural Biology PhD Projects, Programmes & Scholarships in the UK

Structural Biology PhD Projects, Programmes & Scholarships in the UK

We have 108 Structural Biology PhD Projects, Programmes & Scholarships in the UK

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