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Structural Biology PhD Projects, Programmes & Scholarships in the UK

We have 17 Structural Biology PhD Projects, Programmes & Scholarships in the UK

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Biological Sciences

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United Kingdom

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I am a European student


We have 17 Structural Biology PhD Projects, Programmes & Scholarships in the UK

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Structure-based development of new PROTAC drugs

Proteolysis targeting chimera, or PROTAC in short, are bifunctional small molecules comprising of two active moieties, one binding to the protein of interest and one capable of binding to an intracellular E3 ligase, which ubiquitinates the target protein for degradation. Read more

In situ HDX-MS of membrane protein-ligand interactions

The project aims to develop an HDX-MS workflow to profile ligand-membrane protein interactions. The identification of hits with high selectivity constitutes an important landmark for the design and development of novel therapeutics. Read more

Structure and function of Batten disease proteins

The neuronal ceroid lipofucscinoses are a group of inherited neurodegenerative disorders with primarily childhood onset. The most common form, also known as Batten disease or CLN3 disease, is caused by recessively inherited mutation in the CLN3 gene. Read more
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Probing enzyme reaction cascades in antibiotic biosynthesis at atomic resolution by NMR

Polyketide biosynthetic pathways generate vast numbers of diverse compounds that represent one of the largest collections of chemical structures with biological… Read more
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Modulation of Protein Function using Molecular Imprinting

Molecularly Imprinted Polymers (MIPs) are simple, elegant biomimetics that incorporate binding sites bearing steric and chemical functionality complementary to a given target. Read more

High-Resolution Ptychographic Cryogenic Electron Microscopy

Regarding transmission electron microscopy (TEM), as the electron wave passes through a sample, an electron scatters, producing an exit wavefront rich in information. Read more

Mapping the conformational signalling landscape of G protein-coupled receptors (GPCRs)

As a research group we are interested in the role that G protein-coupled receptors (GPCRs) play in cellular signalling. We aim at understanding how these membrane embedded receptors function and what external factors influence their behaviour as sensors of the cell. Read more

Structure, regulation and dynamics of small G proteins and their interactions with membranes and effector proteins

Our lab are interested in cell signalling via small G proteins of the Ras superfamily. We use a range of biochemical, biophysical and structural approaches to understand these fascinating proteins, which are involved in multiple cellular processes and are often deregulated in diseases such as cancer. Read more

EPSRC CDT in Science and Applications of Graphene and Related Nanomaterials (Graphene NOWANO)

 . Established in 2013 with EPSRC funding and now supported by the University of Manchester and industry, Graphene NOWNANO CDT offers PhD training in science, technology and applications of the fast-growing family of two-dimensional materials. Read more

EPSRC CDT in Science and Applications of Graphene and Related Nanomaterials (Graphene NOWANO)

 . Established in 2013 with EPSRC funding and now supported by the University of Manchester and industry, Graphene NOWNANO CDT offers PhD training in science, technology and applications of the fast-growing family of two-dimensional materials. Read more

EPSRC Centre for Doctoral Training in Molecular Sciences for Medicine - 4 year PhD Studentships

Applications are welcome for one further project within our CDT to commence in September 2022. Please visit our webpage for up to date information regarding the EPSRC Centre for Doctoral Training (CDT) in Molecular Sciences for Medicine (MoSMed). Read more

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